Asymmetric Total Syntheses of (+)-Davisinol and (+)-18-Benzoyldavisinol: A HAT-Initiated Transannular Redox Radical Approach

Stereocontrolled Radical Bicyclizations of Oxygenated Precursors Enable Short Syntheses of Oxidized Abietane Diterpenoids

(2021) Darius Vrubliauskas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Total Synthesis of Hetidine-Type C20-Diterpenoid Alkaloids: (+)-Talassimidine and (+)-Talassamine

(2021) Quanzheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging chemoenzymatic and radical-based retrosynthetic logic for rapid and modular synthesis of oxidized meroterpenoids

(2020) Jian Li et al.   Nature Chemistry

Total Synthesis of Liangshanone

(2020) Hong‐Xiu Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of (−)-Daphnezomines A and B

(2020) Guangpeng Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Total Synthesis of Dankasterones A and B and Periconiastone A Through Radical Cyclization

(2020) Pengquan Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Divergent Total Syntheses of (−)-Pseudocopsinine and (−)-Minovincinine

(2020) Xianhuang Zeng et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Syntheses of Rhodomolleins XX and XXII: A Reductive Epoxide-Opening/Beckwith-Dowd Approach

(2019) Kuan Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Total Synthesis of Arcutinidine, Arcutinine, and Arcutine

(2019) Shupeng Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of the Diterpenoid Alkaloid Arcutinidine Using a Strategy Inspired by Chemical Network Analysis

(2019) Kyle R Owens et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Radical-Polar Crossover Annulation To Access Terpenoid Motifs

(2019) William P. Thomas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Advances Towards Syntheses of Diterpenoid Alkaloids

(2019) Christian Dank et al.   SYNTHESIS-STUTTGART

Total Synthesis of Viridin and Viridiol

(2019) Yang Ji et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Case for Bond-Network Analysis in Bridged Polycyclic Complex Molecule Synthesis: Hetidine and Hetisine Diterpenoid Alkaloids

(2019) Nicolle A. Doering et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Unified Approach for the Assembly of Atisine- and Hetidine-type Diterpenoid Alkaloids: Total Syntheses of Azitine and the Proposed Structure of Navirine C

(2018) Jie Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Benzyne Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine)

(2018) Kevin G. M. Kou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Septedine and 7-Deoxyseptedine

(2018) Shupeng Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Aplysiasecosterol A

(2018) Zhaohong Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Twelve-Step Asymmetric Synthesis of (−)-Nodulisporic Acid C

(2018) Nicole A. Godfrey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The High Chemofidelity of Metal-Catalyzed Hydrogen Atom Transfer

(2018) Samantha A. Green et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Unifying Synthesis Approach to the C18-, C19-, and C20-Diterpenoid Alkaloids

(2017) Kevin G. M. Kou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fe-Catalyzed C–C Bond Construction from Olefins via Radicals

(2017) Julian C. Lo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enabling syntheses of diterpenoid alkaloids and related diterpenes by an oxidative dearomatization/Diels–Alder cycloaddition strategy

(2017) Xiao-Yu Liu et al.   NATURAL PRODUCT REPORTS

Total Synthesis of Notoamides F, I, and R and Sclerotiamide

(2016) Benxiang Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Atisine, Ajaconine, Denudatine, and Hetidine Diterpenoid Alkaloids by a Bioinspired Approach

(2016) Xiao-Huan Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Divergent Total Synthesis of Atisane-Type Diterpenoids

(2016) Guili Zhu et al.   CHEMICAL RECORD

Mn-, Fe-, and Co-Catalyzed Radical Hydrofunctionalizations of Olefins

(2016) Steven W. M. Crossley et al.   CHEMICAL REVIEWS

Syntheses of Denudatine Diterpenoid Alkaloids: Cochlearenine, N-Ethyl-1α-hydroxy-17-veratroyldictyzine, and Paniculamine

(2016) Kevin G. M. Kou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ph(i-PrO)SiH2: An Exceptional Reductant for Metal-Catalyzed Hydrogen Atom Transfers

(2016) Carla Obradors et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis of atropurpuran

(2016) Jing Gong et al.   Nature Communications

Collective Total Syntheses of Atisane-Type Diterpenes and Atisine-Type Diterpenoid Alkaloids: (±)-Spiramilactone B, (±)-Spiraminol, (±)-Dihydroajaconine, and (±)-Spiramines C and D

(2015) Hang Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evaluation of Aconitum diterpenoid alkaloids as antiproliferative agents

(2015) Koji Wada et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Concise Approach to Paxilline Indole Diterpenes

(2015) David T. George et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Network-analysis-guided synthesis of weisaconitine D and liljestrandinine

(2015) C. J. Marth et al.   NATURE

Total Synthesis of Atisane-Type Diterpenoids and Related Diterpenoid Alkaloids

(2015) Bo Liu et al.   SYNTHESIS-STUTTGART

Ongoing Pursuit of Diterpenoid Alkaloids: A Synthetic View

(2015) Xiao-Yu Liu et al.   Asian Journal of Organic Chemistry

Total Synthesis of (±)-Hippolachnin A

(2014) Stefan A. Ruider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Simple, Chemoselective, Catalytic Olefin Isomerization

(2014) Steven W. M. Crossley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (−)-Lepenine

(2014) Yoshitake Nishiyama et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unified Approach to ent-Atisane Diterpenes and Related Alkaloids: Synthesis of (−)-Methyl Atisenoate, (−)-Isoatisine, and the Hetidine Skeleton

(2014) Emily C. Cherney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Practical and Catalytic Reductive Olefin Coupling

(2014) Julian C. Lo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Syntheses of (−)-Kopsifoline D and (−)-Deoxoapodine: Divergent Total Synthesis via Late-Stage Key Strategic Bond Formation

(2014) Kiyoun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic strategies toward hetidine and hetisine-type diterpenoid alkaloids

(2014) Amy M. Hamlin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Kinetic Resolution of Racemic 2-Hydroxy-γ-butyrolactones by Asymmetric Esterification Using Diphenylacetic Acid with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst

(2013) Kenya Nakata et al.   ORGANIC LETTERS

Iridium-Catalyzed Reduction of Secondary Amides to Secondary Amines and Imines by Diethylsilane

(2012) Chen Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron(III)/NaBH4-Mediated Additions to Unactivated Alkenes: Synthesis of Novel 20′-Vinblastine Analogues

(2012) Erick K. Leggans et al.   ORGANIC LETTERS

Terpenoid-Alkaloids: Their Biosynthetic Twist of Fate and Total Synthesis

(2011) Emily C. Cherney et al.   ISRAEL JOURNAL OF CHEMISTRY

Synthesis and Catalytic Properties of 4-Aryl-2,3-dihydro-4H-pyrimido[2,3-b]benzothiazoles for Asymmetric Acyl or Carboxyl Group Transfer Reactions

(2011) Baby Viswambharan et al.   JOURNAL OF ORGANIC CHEMISTRY

Diterpenoid alkaloids

(2010) Feng-Peng Wang et al.   NATURAL PRODUCT REPORTS

Isothiourea-Catalyzed Enantioselective Carboxy Group Transfer

(2009) Caroline Joannesse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Effects of a Novel Anti-arrhythmic Drug, Acehytisine Hydrochloride, on the HumanEther-a-go-go RelatedGene K+Channel and Its Trafficking

(2009) Xingfu Huang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Kinetic Resolution of the Racemic 2-Hydroxyalkanoates Using the Enantioselective Mixed-Anhydride Method with Pivalic Anhydride and a Chiral Acyl-Transfer Catalyst

(2009) Isamu Shiina et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structure-activity relationships between the Aconitum C20-diterpenoid alkaloid derivatives and the growth suppressive activities of Non-Hodgkin’s lymphoma Raji cells and human hematopoietic stem/progenitor cells

(2009) Masaharu Hazawa et al.   INVESTIGATIONAL NEW DRUGS

Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues

(2009) Hayato Ishikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Redox Radical Cyclizations of 1,6-Dienes and Enynes

(2009) Tsuyoshi Taniguchi et al.   ORGANIC LETTERS

Homobenzotetramisole:  An Effective Catalyst for Kinetic Resolution of Aryl-Cycloalkanols

(2008) Vladimir B. Birman et al.   ORGANIC LETTERS

Asymmetric Synthetic Access to the Hetisine Alkaloids: Total Synthesis of (+)-Nominine

(2007) Kevin M. Peese et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct Coupling of Catharanthine and Vindoline to Provide Vinblastine:  Total Synthesis of (+)- andent-(−)-Vinblastine

(2007) Hayato Ishikawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY