Potential toxicity of nanoparticles on the reproductive system animal models: A Review

The Impact of Zinc Oxide Nanoparticles on Male (In)Fertility

(2020) Ana Rita Pinho et al.   Materials

Fe3O4 Nanoparticles Attenuated Salmonella Infection in Chicken Liver Through Reactive Oxygen and Autophagy via PI3K/Akt/mTOR Signaling

(2020) Yiru Shen et al.   Frontiers in Physiology

Specificity of Biogenic Selenium Nanoparticles for Prostate Cancer Therapy With Reduced Risk of Toxicity: An in vitro and in vivo Study

(2020) Praveen Sonkusre   Frontiers in Oncology

Surface charge-dependent bioaccumulation dynamics of silver nanoparticles in freshwater algae

(2020) Jilai Zhang et al.   CHEMOSPHERE

Overexpression of p62 Induces Autophagy and Promotes Proliferation, Migration and Invasion of Nasopharyngeal Carcinoma Cells through Promoting ERK Signaling Pathway

(2020) Qiong Wu et al.   CURRENT CANCER DRUG TARGETS

Selenium ameliorates cadmium-induced mouse leydig TM3 cell apoptosis via inhibiting the ROS/JNK /c-jun signaling pathway

(2020) Xiangmei Ren et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure

(2020) Zannatul Ferdous et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Acute Damage to the Sperm Quality and Spermatogenesis in Male Mice Exposed to Curcumin-Loaded Nanoparticles

(2020) Xiaoyu Xia et al.   International Journal of Nanomedicine

Toxicity and antimicrobial effect of silver nanoparticles in swine sperms

(2020) Francisco Pérez-Duran et al.   Systems Biology in Reproductive Medicine

Iron Oxide Nanoparticle-Induced Autophagic Flux Is Regulated by Interplay between p53-mTOR Axis and Bcl-2 Signaling in Hepatic Cells

(2020) Mariia Uzhytchak et al.   Cells

Effect of GABA-T on Reproductive Function in Female Rats

(2020) Wenyu Si et al.   Animals

Review on Metal-Based Nanoparticles: Role of Reactive Oxygen Species in Renal Toxicity

(2020) Pouran Makhdoumi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Advances in Gold Nanoparticle-Based Combined Cancer Therapy

(2020) Kyle Bromma et al.   Nanomaterials

Targeting the mTOR Signaling Pathway Utilizing Nanoparticles: A Critical Overview

(2019) Mariia Lunova et al.   Cancers

Biological Applications and Toxicity Minimization of Semiconductor Quantum Dots

(2019) Samira Filali et al.   TRENDS IN BIOTECHNOLOGY

Synthesis, spectral analysis, crystal structure, Hirshfeld surface analyses, thermal behavior of two new nickel complexes and usage as precursor for preparation of Ni/NiO nanoparticles

(2019) M. Tavassoli et al.   POLYHEDRON

Synthesis of Baicalein Modified Cerium Oxide Nanoparticles for Inhibitory Activation of NF-κB and Mitogen-Activated Protein Kinase Signals in Rotenone-Induced Parkinsonian Rats

(2019) Zhuang Zhang et al.   Science of Advanced Materials

The interaction between nanoparticles-protein corona complex and cells and its toxic effect on cells

(2019) Na Liu et al.   CHEMOSPHERE

Cytotoxicity, Oxidative Stress, and Autophagy Effects of Tantalum Nanoparticles on MC3T3-E1 Mouse Osteoblasts

(2019) Peihuan Wang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Green synthesis, characterization and catalytic degradation studies of gold nanoparticles against congo red and methyl orange

(2018) C. Umamaheswari et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

The inflammatory response to silver and titanium dioxide nanoparticles in the central nervous system

(2018) Tianshu Wu et al.   Nanomedicine

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

(2018) Alyona Sukhanova et al.   Nanoscale Research Letters

Enhanced steroidogenic and altered antioxidant response by ZnO nanoparticles in mouse testis Leydig cells

(2018) Nisha Bara et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

(2018) Alyona Sukhanova et al.   Nanoscale Research Letters

The effect of silver nanoparticles on the reproductive system of adult male rats: A morphological, histological and DNA integrity study

(2018) Nasibeh Fathi et al.   Advances in Clinical and Experimental Medicine

Health Concerns of Various Nanoparticles: A Review of Their in Vitro and in Vivo Toxicity

(2018) Marziyeh Ajdary et al.   Nanomaterials

Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice

(2017) Jianhui Liu et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells

(2017) Ding-Ping Bai et al.   International Journal of Nanomedicine

Silica nanoparticles induce autophagy dysfunction via lysosomal impairment and inhibition of autophagosome degradation in hepatocytes

(2017) Ji Wang et al.   International Journal of Nanomedicine

Ultrastructural Investigation of Pelvic Peritoneum in Patients With Chronic Pelvic Pain and Subtle Endometriosis in Association With Chromoendoscopy

(2017) Abolfazl Mehdizadehkashi et al.   Journal of Minimally Invasive Gynecology

Mitophagy in neurodegeneration and aging

(2017) Elayne M. Fivenson et al.   NEUROCHEMISTRY INTERNATIONAL

Dose-dependent effect of silver nanoparticles (AgNPs) on fertility and survival of Drosophila: An in-vivo study

(2017) Akanksha Raj et al.   PLoS One

A review of reproductive and developmental toxicity of silver nanoparticles in laboratory animals

(2017) Makoto Ema et al.   REPRODUCTIVE TOXICOLOGY

Mitochondrial homeostasis in adipose tissue remodeling

(2017) Svetlana Altshuler-Keylin et al.   Science Signaling

Mitochondrial Function and Cell Size: An Allometric Relationship

(2017) Teemu P. Miettinen et al.   TRENDS IN CELL BIOLOGY

Oocyte exposure to ZnO nanoparticles inhibits early embryonic development through the γ-H2AX and NF-κB signaling pathways

(2017) Jing Liu et al.   Oncotarget

Mitochondrial homeostasis in adipose tissue remodeling

(2017) Svetlana Altshuler-Keylin et al.   Science Signaling

Toxicity of Nanoparticles on the Reproductive System in Animal Models: A Review

(2017) Rahim Dad Brohi et al.   Frontiers in Pharmacology

Inhibition of autophagy overcomes the nanotoxicity elicited by cadmium-based quantum dots

(2016) Jiajun Fan et al.   BIOMATERIALS

Mitophagy: a balance regulator of NLRP3 inflammasome activation

(2016) Min-Ji Kim et al.   BMB Reports

Repeated exposure to iron oxide nanoparticles causes testicular toxicity in mice

(2016) Kiruthika Sundarraj et al.   ENVIRONMENTAL TOXICOLOGY

Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

(2016) Caixia Guo et al.   International Journal of Nanomedicine

Querectin Alleviates Zinc Oxide Nanoreprotoxicity in Male Albino Rats

(2016) Mohamed M. A. Hussein et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Nanoparticle transport across the placental barrier: pushing the field forward!

(2016) Carina Muoth et al.   Nanomedicine

Mechanisms of silver nanoparticle-induced toxicity and important role of autophagy

(2016) Bin-Hsu Mao et al.   Nanotoxicology

Graphene oxide quantum dots disrupt autophagic flux by inhibiting lysosome activity in GC-2 and TM4 cell lines

(2016) Xiaoli Ji et al.   TOXICOLOGY

Sublethal effects of zinc oxide nanoparticles on male reproductive cells

(2016) Qian Liu et al.   TOXICOLOGY IN VITRO

Silica nanoparticles induce start inhibition of meiosis and cell cycle arrest via down-regulating meiotic relevant factors

(2016) Jin Zhang et al.   Toxicology Research

Reproductive toxicity and gender differences induced by cadmium telluride quantum dots in an invertebrate model organism

(2016) Si-Qi Yan et al.   Scientific Reports

ER stress: Autophagy induction, inhibition and selection

(2015) Harun-Or Rashid et al.   Autophagy

Differential regulatory functions of three classes of phosphatidylinositol and phosphoinositide 3-kinases in autophagy

(2015) Xinlei Yu et al.   Autophagy

ER Stress and Autophagy

(2015) W. Lee et al.   CURRENT MOLECULAR MEDICINE

Inhalation of titanium dioxide induces endoplasmic reticulum stress-mediated autophagy and inflammation in mice

(2015) Kyeong-Nam Yu et al.   FOOD AND CHEMICAL TOXICOLOGY

One-pot synthesis of FePt/CNTs nanocomposites for efficient cellular imaging and cancer therapy

(2015) Weihong Chen et al.   JOURNAL OF NANOPARTICLE RESEARCH

Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress

(2015) Hui-Wen Chiu et al.   Nanoscale

Prenatal toxicity of synthetic amorphous silica nanomaterial in rats

(2015) Thomas Hofmann et al.   REPRODUCTIVE TOXICOLOGY

Inhibition of autophagy enhances the anticancer activity of silver nanoparticles

(2014) Jun Lin et al.   Autophagy

The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers

(2014) Shaofei Wang et al.   BIOMATERIALS

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

Differential Effect of Solar Light in Increasing the Toxicity of Silver and Titanium Dioxide Nanoparticles to a Fish Cell Line and Zebrafish Embryos

(2014) Saji George et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Nickel Nanoparticles Exposure and Reproductive Toxicity in Healthy Adult Rats

(2014) Lu Kong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway

(2014) Duan et al.   International Journal of Nanomedicine

Mechanisms of nanotoxicity: Generation of reactive oxygen species

(2014) Peter P. Fu et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Effect of silver nanoparticles on mitogen-activated protein kinases activation: role of reactive oxygen species and implication in DNA damage

(2014) A. Rinna et al.   MUTAGENESIS

A general mechanism for intracellular toxicity of metal-containing nanoparticles

(2014) Stefania Sabella et al.   Nanoscale

Inhibition of autophagy protects against PAMAM dendrimers-induced hepatotoxicity

(2014) Yubin Li et al.   Nanotoxicology

Daily exposure to silver nanoparticles during prepubertal development decreases adult sperm and reproductive parameters

(2014) Francielle T. Mathias et al.   Nanotoxicology

Size dependent translocation and fetal accumulation of gold nanoparticles from maternal blood in the rat

(2014) Manuela Semmler-Behnke et al.   Particle and Fibre Toxicology

Investigating the Toxicity, Uptake, Nanoparticle Formation and Genetic Response of Plants to Gold

(2014) Andrew F. Taylor et al.   PLoS One

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

(2014) Ruchi Roy et al.   TOXICOLOGY LETTERS

ERK pathway is activated in bare-FeNPs-induced autophagy

(2013) Eun-Jung Park et al.   ARCHIVES OF TOXICOLOGY

Cadmium-Based Quantum Dot Induced Autophagy Formation for Cell Survival via Oxidative Stress

(2013) Yueh-Hsia Luo et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The effect of zinc oxide nanoparticles on mouse spermatogenesis

(2013) Ali Reza Talebi et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Exposure to zinc oxide nanoparticles affects reproductive development and biodistribution in offspring rats

(2013) Eunhye Jo et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Effects of mesoporous silica nanoparticles upon the function of mammalian sperm in vitro

(2013) Natalia Barkalina et al.   Nanomedicine-Nanotechnology Biology and Medicine

Titanium dioxide nanoparticles increase inflammatory responses in vascular endothelial cells

(2013) Sung Gu Han et al.   TOXICOLOGY

Zinc oxide nanoparticle induced autophagic cell death and mitochondrial damage via reactive oxygen species generation

(2013) Kyeong-Nam Yu et al.   TOXICOLOGY IN VITRO

Different biokinetics of nanomedicines linking to their toxicity; an overview

(2013) Sara Mostafalou et al.   DARU-Journal of Pharmaceutical Sciences

Distribution and histologic effects of intravenously administered amorphous nanosilica particles in the testes of mice

(2012) Yuki Morishita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Accumulation of nanocarriers in the ovary: A neglected toxicity risk?

(2012) Andreas Schädlich et al.   JOURNAL OF CONTROLLED RELEASE

Ovarian dysfunction and gene-expressed characteristics of female mice caused by long-term exposure to titanium dioxide nanoparticles

(2012) Guodong Gao et al.   JOURNAL OF HAZARDOUS MATERIALS

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Cadmium Associated With Inhaled Cadmium Oxide Nanoparticles Impacts Fetal and Neonatal Development and Growth

(2012) Jason L. Blum et al.   TOXICOLOGICAL SCIENCES

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways

(2011) Yang Li et al.   BIOMATERIALS

Size-dependent endocytosis of single gold nanoparticles

(2011) Yuping Shan et al.   CHEMICAL COMMUNICATIONS

Studies of Intracorneal Distribution and Cytotoxicity of Quantum Dots: Risk Assessment of Eye Exposure

(2011) Tsung-Rong Kuo et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Silica and titanium dioxide nanoparticles cause pregnancy complications in mice

(2011) Kohei Yamashita et al.   Nature Nanotechnology

A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt–TSC2-mTOR signaling

(2011) H-L Liu et al.   Cell Death & Disease

Mechanisms and measurements of nanomaterial-induced oxidative damage to DNA

(2010) Elijah J. Petersen et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Caspase Sensitive Gold Nanoparticle for Apoptosis Imaging in Live Cells

(2010) In-Cheol Sun et al.   BIOCONJUGATE CHEMISTRY

Deciphering the Role of PI3K/Akt/mTOR Pathway in Breast Cancer Biology and Pathogenesis

(2010) Priscilla F. McAuliffe et al.   Clinical Breast Cancer

Surface Charge-Dependent Toxicity of Silver Nanoparticles

(2010) Amro M. El Badawy et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Uptake and biological effects of chitosan-capped gold nanoparticles on Chinese Hamster Ovary cells

(2010) Sanda C. Boca et al.   Materials Science & Engineering C-Materials for Biological Applications

Repeated administrations of carbon nanotubes in male mice cause reversible testis damage without affecting fertility

(2010) Yuhong Bai et al.   Nature Nanotechnology

Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction

(2010) Denise N. Johnson-Lyles et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism

(2009) Wei Bai et al.   JOURNAL OF NANOPARTICLE RESEARCH

PAMAM Nanoparticles Promote Acute Lung Injury by Inducing Autophagic Cell Death through the Akt-TSC2-mTOR Signaling Pathway

(2009) C. Li et al.   Journal of Molecular Cell Biology

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

EFFECTS OF PARTICLE COMPOSITION AND SPECIES ON TOXICITY OF METALLIC NANOMATERIALS IN AQUATIC ORGANISMS

(2008) Robert J. Griffitt et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1α-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer

(2007) Stephen L. Archer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY