Article
Chemistry, Physical
Constantin Kappas
Summary: This article discusses the management and evaluation of radiation doses for pregnant women and pregnant workers in clinical settings where ionizing radiation is used. The study found that the majority of conventional radiographic procedures and diagnostic procedures in nuclear medicine are at doses much lower than the exposure associated with fetal harm. However, certain therapies in nuclear medicine, Radiation Therapy, multiple CT scans, and invasive radiology have the potential to cause serious damage to the fetus.
RADIATION PHYSICS AND CHEMISTRY
(2022)
Review
Oncology
Iman Salehi, Ludmila Porto, Christine Elser, Jessica Singh, Samuel Saibil, Cynthia Maxwell
Summary: Immune checkpoint inhibitors (ICIs) have become the standard of care for multiple malignancies, but their effects on human pregnancy are largely unknown. This study reviews previous cases of maternal exposure to ICIs and presents a case series of two pregnant patients exposed to immunotherapy, adding to the existing evidence.
JOURNAL OF IMMUNOTHERAPY
(2022)
Article
Environmental Sciences
Shu Sun, Xiaoyu Wang, Liu Ding, Qi Zhang, Na Li, Xinmiao Sui, Changlian Li, Liangliang Ju, Qihong Zhao, Hongbo Chen, Rui Ding, Jiyu Cao
Summary: The study found that preconceptional exposure to PM2.5, PM10, and O3 was associated with the risk of TOP, but not with congenital malformations. Pregnant women of advanced ages were more susceptible to the effects of air pollution exposure, with PM2.5 showing a significant impact in the cold season.
ENVIRONMENTAL RESEARCH
(2021)
Article
Medicine, General & Internal
Takaaki Yoshimura, Atsushi Hasegawa, Shoki Kogame, Keiichi Magota, Rina Kimura, Shiro Watanabe, Kenji Hirata, Hiroyuki Sugimori
Summary: This study aimed to investigate whether the SR deep learning technique could enhance the image quality of short-acquisition PET images and thereby reduce the injected FDG dose. The results showed that the SR-PET image was more similar to the 100% PET image, indicating a significant improvement in image quality.
Review
Environmental Sciences
Mark P. Little, Richard Wakeford, Simon D. Bouffler, Kossi Abalo, Michael Hauptmann, Nobuyuki Hamada, Gerald M. Kendall
Summary: Evidence suggests an excess risk of childhood cancer after medical diagnostic radiation exposure in utero or in childhood, with recent studies indicating reduced risk. Postnatal exposure to diagnostic radiation is associated with significant excess risks of leukemia, brain, and solid cancers, with variations in risk by cancer type and type of exposure. However, there is significant heterogeneity among studies on postnatal exposure, which affects the strength of evidence for a causal relationship between childhood radiation imaging and subsequent cancer risk.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Pediatrics
Yuhki Koga, Masafumi Sanefuji, Syunichiro Toya, Utako Oba, Kentaro Nakashima, Hiroaki Ono, Shunsuke Yamamoto, Maya Suzuki, Yuri Sonoda, Masanobu Ogawa, Hiroyuki Yamamoto, Koichi Kusuhara, Shouichi Ohga, Michihiro Kamijima, Shin Yamazaki, Yukihiro Ohya, Reiko Kishi, Nobuo Yaegashi, Koichi Hashimoto, Chisato Mori, Shuichi Ito, Zentaro Yamagata, Hidekuni Inadera, Takeo Nakayama, Hiroyasu Iso, Masayuki Shima, Youichi Kurozawa, Narufumi Suganuma, Koichi Kusuhara, Takahiko Katoh
Summary: This study examined the potential association between maternal occupational exposure and the occurrence of neuroblastoma in offspring. Maternal exposure to ionizing radiation was found to be closely associated with infantile neuroblastoma. Further studies involving large pediatric cancer registries are needed to confirm these preliminary findings.
PEDIATRIC RESEARCH
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
James G. Mainprize, Martin J. Yaffe, Tanya Chawla, Phyllis Glanc
Summary: This study aims to assess the effects of ionizing radiation on the conceptus during pregnancy and explore strategies to mitigate potential harms. By combining data from peer-reviewed literature and modeling, the study estimates the total doses received from specific radiological procedures. It is found that procedures excluding the conceptus have low doses below the tissue reaction threshold, while procedures including the conceptus may approach or exceed thresholds, requiring careful risk-benefit evaluation. Emerging technologies such as whole-body DWI/MRI and ultralow dose studies are important for dose reduction strategies.
ABDOMINAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Clemence Baudin, Blandine Vacquier, Guillemette Thin, Lamine Chenene, Joel Guersen, Isabelle Partarrieu, Martine Louet, Hubert Ducou Le Pointe, Stephanie Mora, Catherine Verdun-Esquer, Juliette Feuardent, Frederic Rousseau, Herve Roy, Lynda Bensefa-Colas, Louis Boyer, Marie-Odile Bernier
Summary: Health workers in France exposed to ionizing radiation account for more than 50% of all workers exposed to man-made radiation. This study aimed to evaluate and characterize the trends in radiation exposure among health workers in France between 2009 and 2019. The study found that the average exposure of health workers decreased over the past decade, but there were discrepancies in trends according to professions, departments, hospitals, and gender.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Chen-Ta Yang, Hsu-Heng Yen, Yang-Yuan Chen, Pei-Yuan Su, Siou-Ping Huang
Summary: This retrospective study aimed to evaluate the pattern of radiation exposure in Taiwanese IBD patients. The results showed higher radiation exposure among CD patients compared to patients with UC, indicating the complicated nature of the disease. Therefore, increasing the use of radiation-free medical imaging such as intestinal ultrasound or magnetic resonance imaging should be advocated to decrease the risk of excessive radiation exposure in these patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Environmental Sciences
Younghyun Lee, You Yeon Choi, Mihyun Yang, Young Woo Jin, Ki Moon Seong
Summary: The study found that REM staff generally do not perceive health risks from low-dose radiation exposure in daily life and work environments. Those with a higher level of radiation knowledge tend to have lower risk perceptions of extremely low-dose radiation exposure. Efforts to enhance radiation knowledge through education and training could lead to improved risk evaluation and willingness to respond to large-scale radiological events.
JOURNAL OF ENVIRONMENTAL RADIOACTIVITY
(2021)
Article
Environmental Sciences
Ryan P. W. Kenny, Evelyn Barron Millar, Adenike Adesanya, Catherine Richmond, Fiona Beyer, Carolina Calderon, Judith Rankin, Mireille Toledano, Maria Feychting, Mark S. Pearce, Dawn Craig, Fiona Pearson
Summary: The World Health Organization is conducting a systematic review on the impact of exposure to radiofrequency electromagnetic fields on adverse reproductive outcomes to inform exposure guidelines.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Guo Qi Shan, Ruan Ping, Huang Wei Xu, Huang Dai Zheng, Qiu Jia Chu
Summary: This study found that thyroid hormone levels in medical radiation workers are influenced by gender and radiation dose, and even in low-dose radiation exposure environments, thyroid hormone secretion may be affected.
BIOMEDICAL AND ENVIRONMENTAL SCIENCES
(2021)
Article
Environmental Sciences
Veronica A. Wang, Michael Leung, Longxiang Li, Anna M. Modest, Joel Schwartz, Brent A. Coull, Michele R. Hacker, Blair J. Wylie, Petros Koutrakis, Stefania Papatheodorou
Summary: This study retrospectively examined the association between particle radioactivity (PR) and fetal growth in pregnancies. The results showed that PR exposure was negatively associated with fetal growth before 24 weeks' gestation and positively associated after 24 weeks. This study highlights the importance of considering environmental exposure on fetal development.
AIR QUALITY ATMOSPHERE AND HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Won Jin Lee, Seulki Ko, Ye Jin Bang, Seung-Ah Choe, Yeongchull Choi, Dale L. Preston
Summary: The study aimed to investigate the potential association between occupational radiation exposure and cancer risk among South Korean diagnostic medical radiation workers. Results showed that there was no significant link between radiation doses and cancer incidence in this group, regardless of job title, different lag years, or after excluding thyroid and lung cancers.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Mariam Salameh, Sukaina Zeitoun-Ghandour, Lina Sabra, Ahmad Daher, Mahmoud Khalil, Wissam H. Joumaa
Summary: This study investigated the effects of continuous 24-hour exposure to mobile communication electromagnetic fields on oxidative stress, apoptosis, and inflammation in the liver of rat fetuses. The results showed that exposure to electromagnetic radiation increased oxidative stress, apoptosis, and inflammation, but before a sensitive developmental stage, the mother may provide protection for the embryos.
SCIENTIFIC REPORTS
(2023)
Article
Biology
Werner Ruehm, Tamara Azizova, Simon Bouffler, Harry M. Cullings, Bernd Grosche, Mark P. Little, Roy S. Shore, Linda Walsh, Gayle E. Woloschak
JOURNAL OF RADIATION RESEARCH
(2018)
Article
Environmental Sciences
Andrzej Wojcik, Simon Bouffler, Michael Hauptmann, Preetha Rajaraman
JOURNAL OF RADIOLOGICAL PROTECTION
(2018)
Article
Oncology
Tom Verbiest, Rosemary Finnon, Natalie Brown, Lourdes Cruz-Garcia, Paul Finnon, Grainne O'Brien, Eleanor Ross, Simon Bouffler, Cheryl L. Scudamore, Christophe Badie
Review
Biotechnology & Applied Microbiology
Dietrich Averbeck, Sisko Salomaa, Simon Bouffler, Andrea Ottolenghi, Vere Smyth, Laure Sabatier
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Richard W. Harbron, Elizabeth A. Ainsbury, Simon D. Bouffler, Rick J. Tanner, Mark S. Pearce, Jonathan S. Eakins
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
(2018)
Review
Biology
Nathalie Gault, Tom Verbiest, Christophe Badie, Paul-Henri Romeo, Simon Bouffler
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2019)
Review
Biology
Kunwoo Cho, Tatsuhiko Imaoka, Dmitry Klokov, Tatjana Paunesku, Sisko Salomaa, Mandy Birschwilks, Simon Bouffler, Antone L. Brooks, Tom K. Hei, Toshiyasu Iwasaki, Tetsuya Ono, Kazuo Sakai, Andrzej Wojcik, Gayle E. Woloschak, Yutaka Yamada, Nobuyuki Hamada
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2019)
Letter
Environmental Sciences
Andrzej Wojcik, Simon Bouffler, Michael Hauptmann, Preetha Rajaraman
JOURNAL OF RADIOLOGICAL PROTECTION
(2019)
Review
Biology
R. Julian Preston, Werner Ruhm, Edouard Azzam, John D. Boice, Simon Bouffler, Kathryn D. Held, Mark P. Little, Roy E. Shore, Igor Shuryak, Michael M. Weil
Summary: This contribution aims to review and propose approaches for integrating data from radiation biology and epidemiology studies to enhance low-dose health risk assessment. By leveraging the AOP/KE approach, it suggests developing BBDR models for radiation-induced cancers and circulatory diseases. Tight integration of epidemiology data and radiation biology information is considered necessary to improve low-dose radiation risk estimates.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2021)
Article
Environmental Sciences
C. Clement, W. Ruhm, J. Harrison, K. Applegate, D. Cool, C-M Larsson, C. Cousins, J. Lochard, S. Bouffler, K. Cho, M. Kai, D. Laurier, S. Liu, S. Romanov
Summary: The International Commission on Radiological Protection is reviewing and revising the system of Radiological Protection to adapt to changes in science and society. Emphasis is on enhancing clarity and consistency to improve understanding of the system, leading to better protection and increased harmonization.
JOURNAL OF RADIOLOGICAL PROTECTION
(2021)
News Item
Environmental Sciences
Simon Bouffler
JOURNAL OF RADIOLOGICAL PROTECTION
(2021)
Article
Environmental Sciences
W. Ruehm, C. Clement, D. Cool, D. Laurier, F. Bochud, K. Applegate, T. Schneider, S. Bouffler, K. Cho, G. Hirth, M. Kai, S. Liu, S. Romanov, A. Wojcik
Summary: The International Commission on Radiological Protection (ICRP) has initiated a review and revision process of the current System of Radiological Protection. Through a workshop involving participants from 100 countries, topics such as the scientific basis, concepts, and application of the system were discussed, along with the role of ICRP. Key themes that emerged include radiation-induced effects classification, dose-response relationship understanding, optimization of protection, and ethical considerations.
JOURNAL OF RADIOLOGICAL PROTECTION
(2022)
Review
Biology
W. Ruehm, K. Cho, C. -m. Larsson, A. Wojcik, C. Clement, K. Applegate, F. Bochud, S. Bouffler, D. Cool, G. Hirth, M. Kai, D. Laurier, S. Liu, S. Romanov, T. Schneider
Summary: Ionising radiation has been used for peaceful purposes for over a century, revolutionising health care and promoting well-being. However, a lack of investment in training, education, research, and infrastructure may compromise society's ability to manage radiation risks properly, impacting the well-being of individuals and limiting research and development in radiation technologies.
RADIATION AND ENVIRONMENTAL BIOPHYSICS
(2023)
Article
Biochemistry & Molecular Biology
Serge M. Candeias, Justyna Mika, Paul Finnon, Tom Verbiest, Rosemary Finnon, Natalie Brown, Simon Bouffler, Joanna Polanska, Christophe Badie
CELLULAR AND MOLECULAR LIFE SCIENCES
(2017)