4.1 Article

Radiation exposures in pregnancy, health effects and risks to the embryo/foetus-information to inform the medical management of the pregnant patient

期刊

JOURNAL OF RADIOLOGICAL PROTECTION
卷 41, 期 4, 页码 S522-S539

出版社

IOP Publishing Ltd
DOI: 10.1088/1361-6498/ac1c95

关键词

radiation; pregnancy; medical exposure

向作者/读者索取更多资源

This paper summarizes the sources of radiation exposure to the embryo/fetus in medical settings, highlighting the incomplete understanding of its effects. The lack of specific education and training for pregnant women in the medical field requires case-by-case consideration. Suggestions for future basic science research, education and training, and radiation protection practices are identified.
Generally, intentional exposure of pregnant women is avoided as far as possible in both medical and occupational situations. This paper aims to summarise available information on sources of radiation exposure of the embryo/foetus primarily in medical settings. Accidental and unintended exposure is also considered. Knowledge on the effects of radiation exposure on the developing embryo/foetus remains incomplete-drawn largely from animal studies and two human cohorts but a summary is provided in relation to the key health endpoints of concern, severe foetal malformations/death, future cancer risk, and future impact on cognitive function. Both the specific education and training and also the literature regarding medical management of pregnant females is in general sparse, and consequently the justification and optimisation approaches may need to be considered on a case by case basis. In collating and reviewing this information, several suggestions for future basic science research, education and training, and radiation protection practice are identified.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.1
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Biology

Typical doses and dose rates in studies pertinent to radiation risk inference at low doses and low dose rates

Werner Ruehm, Tamara Azizova, Simon Bouffler, Harry M. Cullings, Bernd Grosche, Mark P. Little, Roy S. Shore, Linda Walsh, Gayle E. Woloschak

JOURNAL OF RADIATION RESEARCH (2018)

Article Environmental Sciences

Considerations on the use of the terms radiosensitivity and radiosusceptibility

Andrzej Wojcik, Simon Bouffler, Michael Hauptmann, Preetha Rajaraman

JOURNAL OF RADIOLOGICAL PROTECTION (2018)

Article Oncology

Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis

Tom Verbiest, Rosemary Finnon, Natalie Brown, Lourdes Cruz-Garcia, Paul Finnon, Grainne O'Brien, Eleanor Ross, Simon Bouffler, Cheryl L. Scudamore, Christophe Badie

LEUKEMIA (2018)

Review Biotechnology & Applied Microbiology

Progress in low dose health risk research Novel effects and new concepts in low dose radiobiology

Dietrich Averbeck, Sisko Salomaa, Simon Bouffler, Andrea Ottolenghi, Vere Smyth, Laure Sabatier

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

The impact of iodinated contrast media on intravascular and extravascular absorbed doses in X-ray imaging: A microdosimetric analysis

Richard W. Harbron, Elizabeth A. Ainsbury, Simon D. Bouffler, Rick J. Tanner, Mark S. Pearce, Jonathan S. Eakins

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS (2018)

Review Biology

Hematopoietic stem and progenitor cell responses to low radiation doses - implications for leukemia risk

Nathalie Gault, Tom Verbiest, Christophe Badie, Paul-Henri Romeo, Simon Bouffler

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2019)

Review Biology

Funding for radiation research: past, present and future

Kunwoo Cho, Tatsuhiko Imaoka, Dmitry Klokov, Tatjana Paunesku, Sisko Salomaa, Mandy Birschwilks, Simon Bouffler, Antone L. Brooks, Tom K. Hei, Toshiyasu Iwasaki, Tetsuya Ono, Kazuo Sakai, Andrzej Wojcik, Gayle E. Woloschak, Yutaka Yamada, Nobuyuki Hamada

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2019)

Letter Environmental Sciences

Reply to Comment on 'Considerations on the use of the terms radiosensitivity and radiosusceptibility'

Andrzej Wojcik, Simon Bouffler, Michael Hauptmann, Preetha Rajaraman

JOURNAL OF RADIOLOGICAL PROTECTION (2019)

Review Biology

Adverse outcome pathways, key events, and radiation risk assessment

R. Julian Preston, Werner Ruhm, Edouard Azzam, John D. Boice, Simon Bouffler, Kathryn D. Held, Mark P. Little, Roy E. Shore, Igor Shuryak, Michael M. Weil

Summary: This contribution aims to review and propose approaches for integrating data from radiation biology and epidemiology studies to enhance low-dose health risk assessment. By leveraging the AOP/KE approach, it suggests developing BBDR models for radiation-induced cancers and circulatory diseases. Tight integration of epidemiology data and radiation biology information is considered necessary to improve low-dose radiation risk estimates.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2021)

Article Environmental Sciences

Keeping the ICRP recommendations fit for purpose

C. Clement, W. Ruhm, J. Harrison, K. Applegate, D. Cool, C-M Larsson, C. Cousins, J. Lochard, S. Bouffler, K. Cho, M. Kai, D. Laurier, S. Liu, S. Romanov

Summary: The International Commission on Radiological Protection is reviewing and revising the system of Radiological Protection to adapt to changes in science and society. Emphasis is on enhancing clarity and consistency to improve understanding of the system, leading to better protection and increased harmonization.

JOURNAL OF RADIOLOGICAL PROTECTION (2021)

News Item Environmental Sciences

US National Academies of Science, Engineering and Medicine launch low dose research strategy initiative

Simon Bouffler

JOURNAL OF RADIOLOGICAL PROTECTION (2021)

Article Environmental Sciences

Summary of the 2021 ICRP workshop on the future of radiological protection

W. Ruehm, C. Clement, D. Cool, D. Laurier, F. Bochud, K. Applegate, T. Schneider, S. Bouffler, K. Cho, G. Hirth, M. Kai, S. Liu, S. Romanov, A. Wojcik

Summary: The International Commission on Radiological Protection (ICRP) has initiated a review and revision process of the current System of Radiological Protection. Through a workshop involving participants from 100 countries, topics such as the scientific basis, concepts, and application of the system were discussed, along with the role of ICRP. Key themes that emerged include radiation-induced effects classification, dose-response relationship understanding, optimization of protection, and ethical considerations.

JOURNAL OF RADIOLOGICAL PROTECTION (2022)

Review Biology

Vancouver call for action to strengthen expertise in radiological protection worldwide

W. Ruehm, K. Cho, C. -m. Larsson, A. Wojcik, C. Clement, K. Applegate, F. Bochud, S. Bouffler, D. Cool, G. Hirth, M. Kai, D. Laurier, S. Liu, S. Romanov, T. Schneider

Summary: Ionising radiation has been used for peaceful purposes for over a century, revolutionising health care and promoting well-being. However, a lack of investment in training, education, research, and infrastructure may compromise society's ability to manage radiation risks properly, impacting the well-being of individuals and limiting research and development in radiation technologies.

RADIATION AND ENVIRONMENTAL BIOPHYSICS (2023)

Article Biochemistry & Molecular Biology

Low-dose radiation accelerates aging of the T-cell receptor repertoire in CBA/Ca mice

Serge M. Candeias, Justyna Mika, Paul Finnon, Tom Verbiest, Rosemary Finnon, Natalie Brown, Simon Bouffler, Joanna Polanska, Christophe Badie

CELLULAR AND MOLECULAR LIFE SCIENCES (2017)

暂无数据