Lipidomics and transcriptomics analyses of altered lipid species and pathways in oxaliplatin-treated colorectal cancer cells

Phosphatidic Acid Stimulates Myoblast Proliferation through Interaction with LPA1 and LPA2 Receptors

(2021) Ana Gomez-Larrauri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of lipidomic profiles associated with drug-resistant prostate cancer cells

(2021) Lishann M. Ingram et al.   Lipids in Health and Disease

Inhibition of fatty acid catabolism augments the efficacy of oxaliplatin-based chemotherapy in gastrointestinal cancers

(2020) Yun Wang et al.   CANCER LETTERS

A role for ceramide glycosylation in resistance to oxaliplatin in colorectal cancer

(2020) James P. Madigan et al.   EXPERIMENTAL CELL RESEARCH

Lipid Peroxidation Plays an Important Role in Chemotherapeutic Effects of Temozolomide and the Development of Therapy Resistance in Human Glioblastoma

(2020) Wei Wu et al.   Translational Oncology

Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis

(2020) Zhiyuan Tang et al.   EBioMedicine

Comparative lipidomics of 5-Fluorouracil–sensitive and –resistant colorectal cancer cells reveals altered sphingomyelin and ceramide controlled by acid sphingomyelinase (SMPD1)

(2020) Jae Hun Jung et al.   Scientific Reports

miR-26a mediates LC-PUFA biosynthesis by targeting the Lxrα-Srebp1 pathway in the marine teleost Siganus canaliculatus

(2020) Cuiying Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer

(2020) Thomas W. Grunt et al.   Scientific Reports

LC-MS-based lipid profile in colorectal cancer patients: TAGs are the main disturbed lipid markers of colorectal cancer progression

(2019) Tong Liu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Differential protein expression profiling by iTRAQ-2D-LC-MS/MS of rats treated with oxaliplatin

(2019) Xianjun Sun et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fatty acid-binding protein 1 increases steer fat deposition by facilitating the synthesis and secretion of triacylglycerol in liver

(2019) Yujuan Wang et al.   PLoS One

Nucleolar Stress Induction by Oxaliplatin and Derivatives

(2019) Emily C. Sutton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets

(2019) Joanna Kopecka et al.   DRUG RESISTANCE UPDATES

PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress

(2018) Afreen Haider et al.   DEVELOPMENTAL CELL

Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation

(2018) Xirui Liu et al.   Molecular Cancer

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

(2018) Alexia Karen Cotte et al.   Nature Communications

Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation

(2018) Daniel Ackerman et al.   Cell Reports

Fatostatin induces pro- and anti-apoptotic lipid accumulation in breast cancer

(2018) Viktor Brovkovych et al.   Oncogenesis

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes

(2017) Barbara Tudek et al.   FREE RADICAL BIOLOGY AND MEDICINE

Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells

(2017) Tomas Ozdian et al.   Journal of Proteomics

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

(2017) Peter M Bruno et al.   NATURE MEDICINE

Specific Triacylglycerols Accumulate via Increased Lipogenesis During 5-FU-Induced Apoptosis

(2016) Nasi Li et al.   ACS Chemical Biology

Protein oxidation and peroxidation

(2016) M. J. Davies   BIOCHEMICAL JOURNAL

The Pharmacological Costs of First-Line Therapies in Unselected Patients With Advanced Colorectal Cancer: A Review of Published Phase III Trials

(2016) Jacopo Giuliani et al.   Clinical Colorectal Cancer

Hepatitis B Virus X Protein Induces Hepatic Steatosis by Enhancing the Expression of Liver Fatty Acid Binding Protein

(2015) Yun-li Wu et al.   JOURNAL OF VIROLOGY

Neutral Lipid Stores and Lipase PNPLA5 Contribute to Autophagosome Biogenesis

(2014) Nicolas Dupont et al.   CURRENT BIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients

(2013) Mika Hilvo et al.   INTERNATIONAL JOURNAL OF CANCER

Angiogenin Stimulates Ribosomal RNA Transcription by Epigenetic Activation of the Ribosomal DNA Promoter

(2013) Jinghao Sheng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-γ-induced vascular smooth muscle cells

(2013) Shui Xiang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

JAK/STAT/SOCS-signaling pathway and colon and rectal cancer

(2011) Martha L. Slattery et al.   MOLECULAR CARCINOGENESIS

Higher expression levels of SOCS 1,3,4,7 are associated with earlier tumour stage and better clinical outcome in human breast cancer

(2010) Walid Sasi et al.   BMC CANCER

Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors

(2010) IM Pires et al.   BRITISH JOURNAL OF PHARMACOLOGY

Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity

(2009) Jing Yan et al.   JOURNAL OF LIPID RESEARCH

Update of the LIPID MAPS comprehensive classification system for lipids

(2008) Eoin Fahy et al.   JOURNAL OF LIPID RESEARCH