The NLRP3 inflammasome mediates liver failure by activating procaspase-1 and pro-IL-1 β and regulating downstream CD40-CD40L signaling

Inflammasomes contributing to inflammation in arthritis

(2020) Lotte Spel et al.   IMMUNOLOGICAL REVIEWS

Dermal fillers do not induce upregulation of NLRP3 inflammasomes or expression of inflammatory cytokines in granulomas

(2020) Markus Reinholz et al.   Journal of Cosmetic Dermatology

Cardiodynamic state is associated with systemic inflammation and fatal acute‐on‐chronic liver failure

(2020) Michael Praktiknjo et al.   LIVER INTERNATIONAL

NLRP3 inflammasome activation from Kupffer cells is involved in liver fibrosis of Schistosoma japonicum-infected mice via NF-κB

(2019) Wen-Juan Zhang et al.   Parasites & Vectors

NLRP3 inflammasome, oxidative stress, and apoptosis induced in the intestine and liver of rats treated with titanium dioxide nanoparticles: in vivo and in vitro study

(2019) Ebrahim Abbasi-Oshaghi et al.   International Journal of Nanomedicine

The selective NLRP3 inflammasome inhibitor MCC950 alleviates cholestatic liver injury and fibrosis in mice

(2019) Junwen Qu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Protective effects of zingerone on lipopolysaccharide-induced hepatic failure through the modulation of inflammatory pathways

(2018) Wonhwa Lee et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Daphnetin alleviates lipopolysaccharide/ d -galactosamine-induced acute liver failure via the inhibition of NLRP3, MAPK and NF-κB, and the induction of autophagy

(2018) Hongming Lv et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fatal acute hepatic failure in a family infected with the hepatitis A virus subgenotype IB

(2017) Yuichi Yoshida et al.   MEDICINE

Prognostic nomogram for acute-on-chronic hepatitis B liver failure

(2017) Su Lin et al.   Oncotarget

Relevance of the NLRP3 Inflammasome in the Pathogenesis of Chronic Liver Disease

(2017) Xiaoqin Wu et al.   Frontiers in Immunology

Serum Glycopatterns as Novel Potential Biomarkers for Diagnosis of Acute-on-Chronic Hepatitis B Liver Failure

(2017) Yaogang Zhong et al.   Scientific Reports

Liver Transplantation in a Patient With CD40 Ligand Deficiency and Hyper-IgM Syndrome: Clinical and Immunological Assessments

(2016) M. Tseng et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Mangiferin alleviates lipopolysaccharide and D-galactosamine-induced acute liver injury by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation

(2016) Chen-wei Pan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Intestinal Dendritic Cells Are Altered in Number, Maturity and Chemotactic Ability in Fulminant Hepatic Failure

(2016) Mei Liu et al.   PLoS One

Plumbagin protects liver against fulminant hepatic failure and chronic liver fibrosis via inhibiting inflammation and collagen production

(2016) Huafeng Wang et al.   Oncotarget

Serum soluble CD40 is associated with liver injury in patients with chronic hepatitis B

(2015) HONG-HUI SHEN et al.   Experimental and Therapeutic Medicine

Potential Use of Biological Proteins for Liver Failure Therapy

(2015) Kazuaki Taguchi et al.   Pharmaceutics

Activation of NLRP3 and AIM2 inflammasomes in Kupffer cells in hepatic ischemia/reperfusion

(2014) Hyo-Yeon Kim et al.   FEBS Journal

Immunotherapeutic interventions in chronic hepatitis B virus infection: A review

(2014) Li Wang et al.   JOURNAL OF IMMUNOLOGICAL METHODS

NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1

(2013) Seok-Joo Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome

(2013) Yang Xiang et al.   PLoS One

Cardiac dysfunction in cirrhosis is not associated with the severity of liver disease

(2012) Manuela Merli et al.   European Journal of Internal Medicine

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies

(2012) Dennis Wolf et al.   PLoS One

The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond

(2011) Cristina Conforti-Andreoni et al.   Cellular & Molecular Immunology

Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis

(2011) Ka-Wing Wong et al.   CELLULAR MICROBIOLOGY

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

(2011) P. Menu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Inflammasomes: Molecular Effectors of Host Resistance Against Bacterial, Viral, Parasitic, and Fungal Infections

(2011) Alexander Skeldon et al.   Frontiers in Microbiology

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Differential Regulation of Caspase-1 Activation via NLRP3/NLRC4 Inflammasomes Mediated by Aerolysin and Type III Secretion System during Aeromonas veronii Infection

(2010) A. J. McCoy et al.   JOURNAL OF IMMUNOLOGY

Chronic antigenic stimuli as a possible explanation for the immunodepression caused by liver cirrhosis

(2009) M. Márquez et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY