An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

The role of Peroxisome Proliferator-Activated Receptors (PPAR) in immune responses

(2020) Anthos Christofides et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Therapeutic trials of biologics in primary biliary cholangitis: An open label study of abatacept and review of the literature

(2019) Christopher L. Bowlus et al.   JOURNAL OF AUTOIMMUNITY

Emerging roles of bile acids in mucosal immunity and inflammation

(2019) Mei Lan Chen et al.   Mucosal Immunology

Primary biliary cholangitis: pathogenesis and therapeutic opportunities

(2019) Aliya F. Gulamhusein et al.   Nature Reviews Gastroenterology & Hepatology

A Bayesian framework for multiple trait colocalization from summary association statistics

(2018) Claudia Giambartolomei et al.   BIOINFORMATICS

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

(2018) Alvaro N. Barbeira et al.   Nature Communications

Genomic atlas of the human plasma proteome

(2018) Benjamin B. Sun et al.   NATURE

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution

(2017) Reedik Mägi et al.   HUMAN MOLECULAR GENETICS

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

(2017) Fang Qiu et al.   Nature Communications

Control for Population Structure and Relatedness for Binary Traits in Genetic Association Studies via Logistic Mixed Models

(2016) Han Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

(2016) Jie Zheng et al.   BIOINFORMATICS

FINEMAP: efficient variable selection using summary data from genome-wide association studies

(2016) Christian Benner et al.   BIOINFORMATICS

Ustekinumab for patients with primary biliary cholangitis who have an inadequate response to ursodeoxycholic acid: A proof-of-concept study

(2016) Gideon M. Hirschfield et al.   HEPATOLOGY

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

Network-based in silico drug efficacy screening

(2016) Emre Guney et al.   Nature Communications

Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES)

(2015) Caroline L Relton et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

(2015) Heather J. Cordell et al.   Nature Communications

Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

(2011) George F Mells et al.   NATURE GENETICS

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

Genetic association of Fc receptor-like 3 polymorphisms with susceptibility to primary biliary cirrhosis: ethnic comparative study in Japanese and Italian patients

(2011) A. Tanaka et al.   TISSUE ANTIGENS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

(2010) Xiangdong Liu et al.   NATURE GENETICS

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

(2010) Jason Z Liu et al.   NATURE GENETICS

Primary Biliary Cirrhosis Associated withHLA, IL12A,andIL12RB2Variants

(2009) Gideon M. Hirschfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH