Article
Food Science & Technology
Thammaporn Junsai, Saranya Poapolathep, Samak Sutjarit, Mario Giorgi, Zhaowei Zhang, Antonio Francesco Logrieco, Peiwu Li, Amnart Poapolathep
Summary: This study investigated the occurrence of multi-mycotoxins in six types of vegetable oils available in Thailand, revealing variations in mycotoxin contamination among different oil samples. The levels of analyzed mycotoxins were found to be below regulatory limits, indicating a low health risk to consumers.
Review
Food Science & Technology
Georg Aichinger, Giorgia Del Favero, Benedikt Warth, Doris Marko
Summary: This review summarizes the current research on the contamination and toxicity of Alternaria and its metabolites in food, highlighting the challenges posed by their chemical complexity and mixture effects, as well as the recent advances in toxicokinetics research, including in vivo studies of genotoxic pollutants such as perylene quinones. Additionally, it discusses the progress in the development of analytical tools based on liquid chromatography/tandem mass spectrometry for a broader spectrum of Alternaria toxins and assessing exposure through human biomonitoring.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2021)
Article
Food Science & Technology
So Young Woo, Sang Yoo Lee, Tae Kyun Jeong, Su Mi Park, Joong Hyuck Auh, Han-Seung Shin, Hyang Sook Chun
Summary: Alternaria mycotoxins are ubiquitous contaminants in agricultural products. This study validated a method for the simultaneous determination of these toxins and investigated their occurrence levels in food samples from the South Korean market. The results showed the average occurrence levels of Alternaria toxins in food and estimated the daily dietary exposure of South Koreans.
Article
Food Science & Technology
Janja Babic, Gabrijela Tavcar-Kalcher, Franci Aco Celar, Katarina Kos, Tanja Knific, Breda Jakovac-Strajn
Summary: This three-year survey investigated the presence and co-occurrence of Alternaria and other mycotoxins in 433 cereal grain samples from Slovenian farms and agricultural cooperatives from 2014 to 2016. Results showed contamination with at least one mycotoxin in the majority of samples, with deoxynivalenol (DON) and tenuazonic acid (TeA) being the most prevalent toxins.
Article
Food Science & Technology
Xiaofeng Ji, Tao Deng, Yingping Xiao, Canghong Jin, Wentao Lyu, Wen Wang, Biao Tang, Zhen Wu, Hua Yang
Summary: Alternaria species are invasive fungi that infect fruits and vegetables, leading to the production of Alternaria toxins, which have negative impacts on commodity values and human health. A reliable analytical method using the QuEChERS extraction method was developed to detect Alternaria toxins in fruits, vegetables, and their derivatives. The method was successfully validated, and approximately 45.2% of the analyzed samples were found to be contaminated with Alternaria toxins, with the highest incidence in fruit and vegetable powders. The study provides important occurrence data and supports the assessment of emerging mycotoxins, specifically Alternaria toxins, in fruit and vegetable products.
Article
Food Science & Technology
Xiaofeng Ji, Yingping Xiao, Canghong Jin, Wen Wang, Wentao Lyu, Biao Tang, Hua Yang
Summary: The occurrence of Alternaria mycotoxins in food commodities sold through e-commerce stores in China is concerning. This study investigated the presence of five Alternaria mycotoxins in 486 samples and found that tenuazonic acid had the highest occurrence rate and concentration in food commodities, followed by tentoxin, alternariol, alternariol methyl ether, and altenuene. Millet and tomato products were found to have higher levels of tenuazonic acid. The chronic dietary exposures to these mycotoxins varied among different age groups, indicating potential health concerns. Strategies should be implemented to reduce the occurrence of Alternaria mycotoxins and minimize dietary risks for humans.
Article
Food Science & Technology
Jiali Xing, Zigeng Zhang, Ruihang Zheng, Xiaorong Xu, Lingyan Mao, Jingping Lu, Jian Shen, Xianjun Dai, Zhenfeng Yang
Summary: A novel and rapid method was established for the simultaneous detection of seven Alternaria toxins in mixed fruit purees, with results showing the presence of toxins in 31 out of 80 samples with a wide range of contamination levels. This method provides a practical tool for the determination of Alternaria toxins in fruit puree samples and could serve as a foundation for establishing limit standards and developing similar detection methods in the future.
Article
Food Science & Technology
Xin Guan, Yuchao Feng, Decheng Suo, Zhiming Xiao, Shi Wang, Ying Liang, Xia Fan
Summary: In this study, a method for detecting 11 mycotoxins in maize was established using multiple-impurity adsorption purification (MIA) technologies and liquid chromatography-tandem mass spectrometry (LC-MS/MS). The validated method was suitable for simultaneous determination of multiple mycotoxins in maize.
Article
Chemistry, Analytical
Wenbo Guo, Junhua Yang, Xueke Niu, Emmanuel K. Tangni, Zhihui Zhao, Zheng Han
Summary: An ultra-high performance liquid chromatography-tandem mass spectrometry method was developed for simultaneous determination of 15 mycotoxins in fruit juices, showing high frequencies of mycotoxins in the samples and demonstrating the susceptibility of fruit juices to various mycotoxins.
ANALYTICAL METHODS
(2021)
Article
Biochemical Research Methods
Jennifer Bates, Adilah Bahadoor, Sheryl A. Tittlemier, Jeremy E. Melanson
Summary: Analysis of low-level organic contaminants in complex matrices is important for global food safety monitoring. Balancing sample throughput with complex experimental designs and sample clean-up to reduce matrix effects is challenging. Multiple strategies exist to mitigate these effects, with internal standard-based methods such as isotope dilution mass spectrometry (IDMS) being the most advantageous.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Review
Food Science & Technology
Maria Luisa Jimenez Medina, Tomas Lafarga, Antonia Garrido Frenich, Roberto Romero-Gonzalez
Summary: Aflatoxins are toxic secondary metabolites that unavoidably appear in the food chain, making their detection and quantification crucial. Various methods have been developed for this purpose, with liquid chromatography coupled to mass spectrometry being highlighted for its effectiveness in cereals, spices, milk, and dairy products.
FOOD REVIEWS INTERNATIONAL
(2021)
Review
Food Science & Technology
Annalisa De Girolamo, Vincenzo Lippolis, Michelangelo Pascale
Summary: This article reviews the relevant literature on liquid chromatography mass spectrometry methods for the analysis of various natural toxins in food. A total of 96 papers from 2011 to 2021 were selected for review. Different approaches in sample preparation, chromatographic separation, and detection mode are discussed. The article particularly focuses on the analytical performance characteristics obtained during the validation process and the application to real samples.
Article
Chemistry, Applied
Hyoyoung Kim, Eun Joo Baek, Yong-Kyoung Kim, Hyejin Park, Suel Hye Hur, Jang-Eok Kim, Ho Jin Kim
Summary: In this study, a specific, reliable, and suitable method for a fast and simultaneous analysis of 335 pesticides in ginseng was developed using liquid chromatography quadrupole mass spectrometry (LC-MS/MS) and gas chromatography quadrupole mass spectrometry (GC-MS/MS). The method was validated for linearity, sensitivity, selectivity, accuracy, and precision, with limits of detection (LOD) and limits of quantification (LOQ) ranging from 0.1-5.8 μg/kg and 0.3-17.5 μg/kg, respectively. Analysis of 467 ginseng samples from 2016 to 2019 revealed pesticide residues in 304 samples, but most were below the standard. The hazard quotient (HQ) of ginseng for detected pesticides was less than 1, indicating low risk.
Review
Food Science & Technology
Cheila Pereira, Sara C. Cunha, Jose O. Fernandes
Summary: Cereals play a crucial role in the nutrition of infants and children, but they can also contain toxic food contaminants such as mycotoxins. While many mycotoxins are regulated, there are emerging mycotoxins that are not yet regulated. This review focuses on recent research studying the levels and digestion behavior of mycotoxins in cereal-based foods for infants and children in Europe, as well as the methods used for their analysis and bioaccessibility evaluation. Studies have shown the co-occurrence of regulated and emerging mycotoxins in children's food, highlighting the need for guidelines on the simultaneous presence of multiple mycotoxins. Limited research has been done on the bioaccessibility of mycotoxins in these food products, but interesting results have been reported regarding the impact of fiber and lipid content on mycotoxin bioaccessibility. LC-MS/MS is considered the most sensitive and accurate method for mycotoxin detection, while in vitro static digestion models are preferred for evaluating bioaccessibility due to their simplicity and accuracy.
Article
Food Science & Technology
Daniela Delfino, Dario Lucchetti, Tabita Mauti, Marta Mancuso, Paolo Di Giustino, Daniela Triolone, Stefano Vaccari, Rossana Claudia Bonanni, Bruno Neri, Katia Russo
Summary: This study aimed to monitor the presence of Ochratoxin A (OTA) in cheeses and pork meat products. A simple and accurate dilute and shoot method was validated for OTA detection in 75 samples, and the importance of further research on exposure and risk assessment for OTA was highlighted.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Environmental Sciences
Celia P. M. Bento, Siebrand van der Hoeven, Xiaomei Yang, Michel M. J. P. M. Riksen, Hans G. J. Mol, Coen J. Ritsema, Violette Geissen
ENVIRONMENTAL POLLUTION
(2019)
Article
Environmental Sciences
Vera Silva, Hans G. J. Mol, Paul Zomer, Marc Tienstra, Coen J. Ritsema, Violette Geissen
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Food Science & Technology
Veronica M. T. Lattanzio, Christoph von Holst, Vincenzo Lippolis, Annalisa De Girolamo, Antonio F. Logrieco, Hans G. J. Mol, Michelangelo Pascale
Article
Environmental Sciences
Govinda Bhandari, Paul Zomer, Kishor Atreya, Hans G. J. Mol, Xiaomei Yang, Violette Geissen
ENVIRONMENTAL RESEARCH
(2019)
Article
Toxicology
A. Oerlemans, L. F. M. Verscheijden, J. G. J. Mol, R. C. H. Vermeulen, J. Westerhout, N. Roeleveld, F. G. M. Russel, P. T. J. Scheepers
ARCHIVES OF TOXICOLOGY
(2019)
Article
Chemistry, Applied
Jacqueline W. H. Biesterbos, Dick T. H. M. Sijm, Ruud van Dam, Hans G. J. Mol
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2019)
Article
Chemistry, Analytical
Michelangelo Pascale, Annalisa De Girolamo, Vincenzo Lippolis, Joerg Stroka, Hans G. J. Mol, Veronica M. T. Lattanzio
JOURNAL OF AOAC INTERNATIONAL
(2019)
Article
Environmental Sciences
E. Polledri, R. Mercadante, R. Nijssen, D. Consonni, H. Mol, S. Fustinoni
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Biochemical Research Methods
Sonia Herrera Lopez, Jonatan Dias, Hans Mol, Andre de Kok
JOURNAL OF CHROMATOGRAPHY A
(2020)
Article
Chemistry, Analytical
Jonatan Dias, Sonia Herrera Lopez, Hans Mol, Andre de Kok
Summary: Hydrophilic interaction liquid chromatography is recognized as an important solution for separating polar compounds not amenable to reverse phase chromatography. This study evaluated three different hydrophilic liquid chromatography stationary phases for the determination of 14 highly polar anionic molecules, showcasing different matrix effects and interactions between compounds. The use of isotopically labeled internal standards enabled acceptable quantitative performance and identification down to 0.02mgkg(-1) for most compounds.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Environmental Sciences
Hans G. J. Mol, Ingrid Elbers, Claudia Paelmke, Daniel Bury, Thomas Goeen, Marta Esteban Lopez, Stefanie Nuebler, Vincent Vaccher, Jean-Philippe Antignac, Darina Dvorakova, Jana Hajslova, Amrit Kaur Sakhi, Cathrine Thomsen, Katrin Vorkamp, Argelia Castano, Holger M. Koch
Summary: A quality assurance/quality control program was implemented in the HBM4EU project, which included four rounds of proficiency tests and involved 28 laboratories. The program resulted in a significant improvement in performance and the establishment of a network of competent laboratories capable of generating comparable and accurate data for biomarker analysis.
Article
Environmental Sciences
Vincent Vaccher, Marta Esteban Lopez, Argelia Castano, Hans Mol, Karin Haji-Abbas-Zarrabi, Daniel Bury, Holger M. Koch, Darina Dvorakova, Jana Hajslova, Stefanie Nuebler, Amrit Kaur Sakhi, Cathrine Thomsen, Katrin Vorkamp, Thomas Goeen, Jean-Philippe Antignac
Summary: The Human Biomonitoring for Europe initiative (HBM4EU) aims to study the exposure of citizens to chemicals and potentially associated health effects. In this project, interlaboratory comparison investigations and external quality assurance schemes were organized to ensure data consistency and reliability. The results showed that Europe has a strong analytical capability for bisphenol A (BPA) and bisphenol S (BPS), while improvements may be needed for bisphenol F (BPF) analysis.
ENVIRONMENTAL RESEARCH
(2022)
Review
Food Science & Technology
Paula Alvito, Ricardo Manuel Assuncao, Lola Bajard, Carla Martins, Marcel J. B. Mengelers, Hans Mol, Sonia Namorado, Annick D. van den Brand, Elsa Vasco, Susana Viegas, Maria Joao Silva
Summary: This article presents the current advances and research needs in studying mycotoxins under the European Human Biomonitoring Initiative. The focus is on the mycotoxins deoxynivalenol (DON) and fumonisin B-1 (FB1), and their potential health impacts. Policy questions regarding hazard characterization, exposure, and risk assessment are addressed. The knowledge gained from this research is expected to support policy making and drive new Human Biomonitoring studies on mycotoxin exposure in Europe.
Article
Public, Environmental & Occupational Health
Stefanie Nuebler, Marta Esteban Lopez, Argelia Castano, Hans G. J. Mol, Johannes Mueller, Moritz Schaefer, Karin Haji-Abbas-Zarrabi, Jana Hajslova, Jana Pulkrabova, Darina Dvorakova, Katerina Urbancova, Holger M. Koch, Jean-Philippe Antignac, Amrit Kaur Sakhi, Katrin Vorkamp, Therese Burkhardt, Max Scherer, Thomas Goeen
Summary: Polycyclic aromatic hydrocarbons (PAHs) were included in the European Human Biomonitoring Initiative (HBM4EU) for harmonization and advancement of human biomonitoring in Europe. A specific QA/QC program using ICIs and EQUASs was developed to ensure comparability and accuracy of analytical laboratories. The study found that 86% of participants achieved satisfactory results in determining 13 PAH metabolites in urine, although low limits of quantification were required. The HBM4EU QA/QC program established an international network of laboratories for comparable analysis of urinary PAH biomarkers.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Biochemical Research Methods
Ivan Aloisi, Hans Mol
Summary: The aim of this research was to develop and validate a method for determining acidic herbicide glucosides, using enzymatic deconjugation as an alternative to alkaline hydrolysis. One specific enzyme was found to be practical and repeatable for deconjugation, leading to complete deconjugation of the glucosides. The method was validated according to established guidelines and a quantitative method for direct determination of intact glucosides was also optimized and validated.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Food Science & Technology
Ewelina Bigoraj, Iwona Kozyra, Agnieszka Kaupke, Zbigniew Osinski, James Lowther, Artur Rzezutka
Summary: The aim of this study was to assess the prevalence of human enteric viruses in mussels sold on the Polish market and study the fecal contamination of shellfish. The study found that human enteric viruses were commonly present in shellfish, with norovirus being the most frequently detected. The study also observed a seasonal distribution pattern of viruses in shellfish samples.
Editorial Material
Food Science & Technology
Bojan Blagojevic, Lis Alban Denmark
Article
Food Science & Technology
Indy Magnus, Fatemeh Abbasi, Hugo Thienpont, Lien Smeesters
Summary: Food safety and quality are increasingly important in our society, driving the development of novel optical food sensing technologies. However, current optical sensing technologies are often limited in their sensitivity and product variability. In this study, we developed a novel pistachio nut screening methodology using fluorescence spectroscopy and advanced chemometrics to simultaneously detect shells, tree parts, and aflatoxins. By optimizing hardware and software parameters, we achieved a high classification accuracy for healthy pistachio kernels.
Article
Food Science & Technology
Xiaodong Wang, Jingqiang Yu, Haixia Wu, Leiying Wu, Wuyunga Borjihan, Cong Wang, Munkhjargal Burenjargal, Alideertu Dong
Summary: This study developed a novel photon-phonon coupling (PPC) cold sterilization technology and compared its effects with low-temperature pasteurization and microwave ultraviolet. The results showed that PPC effectively reduced bacterial count in raw milk with minimal impact on milk quality and nutritional composition.
Review
Food Science & Technology
Riyadh Abdulmalek Hassan, Sharina Abu Hanifah, Lee Yook Heng, Fawaz Al-badaii, Alizar Ulianas
Summary: This study used bibliometric visualisation map analysis to explore the publication outputs, trends, and hotspots for endocrine disruptors (EDMs) biosensor development in relation to mycotoxins. The analysis showed that the current literature primarily focuses on developing biosensors for detecting highly toxic and widely distributed mycotoxins in food, but there needs to be more focus on biosensors for detecting mycotoxins known as endocrine disruptors.
Article
Food Science & Technology
Yajie Zheng, Jianpeng Dou, Changpo Sun, Hujun Liu, Shipei Zhang, Wenfu Wu
Summary: This study investigated the efficiency of modified SA/ll-glucan/Mt microsphere adsorbents in removing DON and ZEN from CSL. The microspheres showed high adsorption capacity, and simple and rapid regeneration was achieved without affecting the removal efficiency of mycotoxins from CSL.
Article
Food Science & Technology
Carlos Adelantado, Jose Angel Salatti-Dorado, Carlos Herrera, Lourdes Arce, Maria Jose Cardador
Summary: High-performance-ion mobility spectrometry (HPIMS) was used for the first time in the analysis of olive oil samples, following a simple liquid-liquid extraction procedure. The developed methodology is user-friendly, fast, and inexpensive, complying with the principles of green chemistry. The proposed approach, combined with multivariate analysis, showed potential in classifying olive oil samples based on their organoleptic quality, with high accuracy rates.
Article
Food Science & Technology
Jia-Wen Wei, Jia-Rong He, Shi-Yi Chen, Yi-Han Guo, Xuan-Zhu Huo, Nuan Zheng, Shuo-Hui Cao, Yao-Qun Li
Summary: Polycyclic aromatic hydrocarbons (PAHs) are a major cause of human cancer. This study developed a quantitative analysis method for PAH4 using the back propagation neural network (BPNN) algorithm and constant wavelength synchronous fluorescence (CWSF) spectra as the data sets. The method can predict the concentrations of PAH4 in edible oil samples without preprocessing or pre-separation. It has been proven to be a powerful tool for the rapid detection of PAH4.
Article
Food Science & Technology
Liyun Chen, Xiumei Li, Jingyi Chen, Ranxun Lin, Yuhan Mai, Yuxin Lin, Guodong Wang, Zheng Chen, Wei Zhang, Jiang Wang, Cai Yuan, Longguang Jiang, Peng Xu, Mingdong Huang
Summary: Food spoilage is primarily caused by microbial contamination. Curcumin has shown moderate antimicrobial activity as a food preservative. This study formulates curcumin with zinc acetate to enhance its efficacy, resulting in Cur-Zn with increased antimicrobial activity against multiple food-contaminating bacteria and fungi. With light illumination, the antimicrobial activity of Cur-Zn is further enhanced due to the photodynamic inactivation (PDI) effect.
Article
Food Science & Technology
Marta Pilar Ortiz-Moriano, Gonzalo Machado-Schiaffino, Eva Garcia-Vazquez, Alba Ardura
Summary: Mislabelling in the global fisheries sector raises concerns about the identity, safety, and sustainability of seafood products. This study examined mislabelling in shrimps and prawns sold in the Spanish market and assessed potential risks of heavy metal ingestion.
Article
Food Science & Technology
Doyeon Kim, Jinwoo Kim, Minsik Kim
Summary: This study demonstrates the enhanced bactericidal activity of engineered lysins fused with amphipathic antimicrobial peptides against Gram-negative bacterium Cronobacter sakazakii. The fusion lysins are capable of disrupting bacterial cells and significantly reducing the risk of infection within a certain range of temperature and pH. Additionally, the study also shows the bactericidal effect of these fusion lysins against other Gram-negative pathogens.
Article
Food Science & Technology
Seul-Ki Park, Kyung-Jin Cho, Du-Min Jo, Young-Mog Kim
Summary: This study presents a new approach for detecting pathogenic Vibrio spp. in contaminated seafood, which combines PCR with a simplified DNA extraction process and pre-culturing step. The method has been validated and shown to be efficient, time-saving, and highly sensitive, offering a potential alternative for improving safety measures in the food industry.
Article
Food Science & Technology
Suwimol Surareungchai, Chaleeda Borompichaichartkul, Chitsiri Rachtanapun, Nutthachai Pongprasert, Pongphen Jitareerat, Varit Srilaong
Summary: This study builds upon previous research and focuses on risk assessment and analysis in the organic salad industry. The results show that previous risk matrix models can be adapted for various raw materials, and preventive control plans can be applied across different aspects of the production process.
Article
Food Science & Technology
Xuan Zhang, Changling Fang, Xiaoyi Lou, Feng Han, Siman Li, Yongfu Shi, Dongmei Huang
Summary: This study aimed to assess the levels of Biogenic amines (BAs) in four common food types in the Chinese market. It was found that cheese and seafood derived product showed higher levels of BAs, and the histamine level in mackerel and yellow rice wine exceeded the limits.
Article
Food Science & Technology
Martina Foschi, Alessandra Biancolillo, Federico Marini, Francesco Cosentino, Francesca Di Donato, Angelo Antonio D'Archivio
Summary: This study aimed to develop a potentially non-destructive and routine-compatible method for the geographical traceability of high-valued Italian chickpeas. By analyzing the spectral information of the outer and inner parts of the kernels, it was found that the spectral analysis of the outer part yielded accurate and reliable results, indicating the possibility of non-destructive authentication.