miRNA‐130b‐5p promotes hepatic stellate cell activation and the development of liver fibrosis by suppressing SIRT4 expression

Downregulated microRNA-130b-5p Prevents Lipid Accumulation and Insulin Resistance in a Murine model of Nonalcoholic Fatty Liver Disease

(2020) Xiaonan Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

EX-527 Prevents the Progression of High-Fat Diet-Induced Hepatic Steatosis and Fibrosis by Upregulating SIRT4 in Zucker Rats

(2020) Amit Kundu et al.   Cells

Ginsenoside Rb1 attenuates microglia activation to improve spinal cord injury via microRNA‐130b‐5p/TLR4/NF‐κB axis

(2020) Dan Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MicroRNA interplay between hepatic stellate cell quiescence and activation

(2020) Devaraj Ezhilarasan   EUROPEAN JOURNAL OF PHARMACOLOGY

Gene regulation by antitumor miR-130b-5p in pancreatic ductal adenocarcinoma: the clinical significance of oncogenic EPS8

(2019) Haruhi Fukuhisa et al.   JOURNAL OF HUMAN GENETICS

Molecular Engineering of the TGF-β Signaling Pathway

(2019) Zhike Zi   JOURNAL OF MOLECULAR BIOLOGY

SIRT4 silencing in tumor-associated macrophages promotes HCC development via PPARδ signalling-mediated alternative activation of macrophages

(2019) Zhi Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019

(2019) Dewidar et al.   Cells

Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway

(2018) Yichuan Xiao et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression

(2018) Mi Jeong Heo et al.   GUT

MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression

(2018) Liping Ma et al.   Cell Death & Disease

MicroRNA-125b Promotes Hepatic Stellate Cell Activation and Liver Fibrosis by Activating RhoA Signaling

(2018) Kai You et al.   Molecular Therapy-Nucleic Acids

Liver cirrhosis

(2018) Richard Barnett   LANCET

SIRT 4 Depletion Promotes HCC Tumorigenesis through Regulating AMPK α/ mTOR Axis

(2018) Yun‐shan Wang et al.   HEPATOLOGY

Oncostatin M causes liver fibrosis by regulating cooperation between hepatic stellate cells and macrophages in mice

(2017) Michitaka Matsuda et al.   HEPATOLOGY

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Targeting the energy guardian AMPK: another avenue for treating cardiomyopathy?

(2016) Tian Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Down-regulation of miR-192-5p protects from oxidative stress-induced acute liver injury

(2016) S. Roy et al.   CLINICAL SCIENCE

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

(2015) Morten A. Karsdal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Suppression of oxidative stress and improvement of liver functions in mice by ursolic acid via LKB1-AMP-activated protein kinase signaling

(2015) Yongbin Yang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Non-coding RNA-mediated epigenetic regulation of liver fibrosis

(2015) Jing-Jing Yang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Metformin prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction

(2015) Rita C. Cavaglieri et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis

(2014) Ali A Mokdad et al.   BMC Medicine

MicroRNAs in liver disease

(2013) Gyongyi Szabo et al.   Nature Reviews Gastroenterology & Hepatology

Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase

(2012) J Darwin King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin attenuates ventricular hypertrophy by activating the AMP-activated protein kinase-endothelial nitric oxide synthase pathway in rats

(2010) Cheng-Xi Zhang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Evolving challenges in hepatic fibrosis

(2010) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology