4.7 Article

Antioxidant and antiproliferative activities in immature and mature wheat kernels

期刊

FOOD CHEMISTRY
卷 196, 期 -, 页码 638-645

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ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2015.09.095

关键词

Immature wheat; Antioxidant capacity; Cell proliferation; Phenolic content; Flavonoid content; Vitamin E

资金

  1. Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries in Gyeonggi-Do, Korea [312049-04-3-SB010]

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The purpose of this study was to investigate health benefit-related parameters such as antioxidant contents and antiproliferative activities in immature wheat compared to mature wheat. Immature and mature wheats were harvested 35 and 45 days after the heading date, respectively; steamed immature wheat was also tested. The phenolic, flavonoid and vitamin E contents of immature and steamed immature wheat were compared with those of mature wheat. Additionally, antiproliferative activities against colon cancer cells (HT-29 and Caco-2) and cervical cancer cells (HeLa) were evaluated in three samples. The immature wheat contained higher phenolic and flavonoid contents but lower vitamin E contents than mature wheat. The antioxidant capacity, as measured by oxygen radical absorbance capacity (ORAC), was higher in immature wheat than in other samples. In the antiproliferation assays, immature wheat had the lowest EC50 values in HT-29 (39.3 mg/mL) and HeLa (31.4 mg/mL) cells, indicating stronger antiproliferative activity. (C) 2015 Elsevier Ltd. All rights reserved.

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