Article
Microbiology
Holly P. Bartholomew, Franz J. Lichtner, Michael Bradshaw, Verneta L. Gaskins, Jorge M. Fonseca, Joan W. Bennett, Wayne M. M. Jurick II
Summary: This study investigated the gene expression during apple fruit decay caused by Penicillium spp. using transcriptomics. It identified differentially expressed genes between two Penicillium species with different levels of aggressiveness and revealed unique genes expressed during apple decay. Gene ontology analysis showed differential regulation in fungal transport and metabolism genes, suggesting a flux in nutrient acquisition and detoxification strategies. Additionally, the study discovered pre-loaded transcripts in conidia from blue mold fungi and revealed the expression dynamics of known fungal virulence factors during apple decay.
Article
Food Science & Technology
Fernando H. Ranjith, Benu Adhikari, Belal J. Muhialdin, Noor Liyana Yusof, Nameer K. Mohammed, Siti Hajar Ariffin, Anis Shobirin Meor Hussin
Summary: This study evaluated the antifungal activity of edible coatings containing bioactive peptides generated from palm kernel cake fermentation. The results showed that incorporating these peptides into chitosan-based coatings effectively inhibited the growth of fungi that infest mangoes, reducing anthracnose and stem-end rot. The chitosan-based coatings also exhibited better peptide release and biodegradability compared to other polysaccharide-based coatings. However, further research is needed to assess the sensory and quality properties of treated mangoes.
Article
Chemistry, Applied
Chaomei Zhou, Jinrong Bai, Fantao Zhang, Rongya Zhang, Xiaolei Zhang, Kai Zhong, Bin Yan
Summary: A multifunctional fruit coating material based on quaternized catechol-functionalized chitosan (CQ-CS) was developed, inspired by the mussel-adhesion strategy. The CQ-CS coating exhibited excellent mechanical properties, universal surface adhesion abilities, antimicrobial and antioxidant capacities without any potential toxicity effects. Using strawberry and banana as model fruits, it was demonstrated that the CQ-CS coating effectively maintained the fruit's firmness and color, decreased the weight loss rate, and prevented microbial growth, thus extending their shelf-life.
CARBOHYDRATE POLYMERS
(2023)
Article
Food Science & Technology
Fernando H. Ranjith, Belal J. Muhialdin, Randolph Arroo, Noor Liyana Yusof, Nameer K. Mohammed, Anis Shobirin Meor Hussin
Summary: Mango is a significant tropical fruit, but post-harvest fungal diseases pose a major problem leading to economic losses and health risks for consumers. While chemical methods have been dominant in fungal control, bio-preservation as an alternative technique offers higher safety and environmental benefits.
Article
Horticulture
Martha Sanchez-Tamayo, Claudia Ochoa-Martinez, Faith Critzer
Summary: This study demonstrates that pectin-based coatings containing oregano essential oil can effectively reduce Salmonella contamination and decrease anthracnose disease on whole mangoes. The coatings also inhibit the growth of fungi and do not affect the quality attributes of coated mango.
Article
Biotechnology & Applied Microbiology
Shen Zhang, Jingyi Wang, Huimin Sun, Jing Yang, Jiajia Zhao, Ying Wang
Summary: This study investigated the activity and mechanisms of hinokitiol against mango anthracnose. The results showed that hinokitiol effectively inhibited the virulence of Colletotrichum gloeosporioides, the fungus causing mango anthracnose, by attenuating cell viability and disrupting cell structure. Furthermore, hinokitiol suppressed the expression of pathogenicity-related genes, leading to reduced infection activity.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2023)
Article
Food Science & Technology
Carolina L. Almeida, Lucas R. F. Figueiredo, Diego V. M. Ribeiro, Adillys M. C. Santos, Evandro L. Souza, Kataryne A. R. Oliveira, Juliano E. Oliveira, Eliton S. Medeiros
Summary: This study investigated the protective effects of a zein coating containing chitosan nanowhiskers (CSW) on the maintenance of fruit quality using guava as a model fruit. The results showed that the addition of CSW prevented microbial growth and preserved fruit quality during storage, effectively extending the shelf life of guava fruits.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Chemistry, Applied
Cui Sun, Jinping Cao, Yue Wang, Lingxia Huang, Jiebiao Chen, Jue Wu, He Zhang, Yunyi Chen, Chongde Sun
Summary: In this study, CAR/HP beta CD-IC inclusion complex was successfully synthesized and used to fabricate pectin-based edible coatings. The inclusion complex showed strong antifungal activities and the edible coating suppressed the growth of fungi as an active packaging material.
FOOD HYDROCOLLOIDS
(2022)
Article
Horticulture
Youwei Yu, Kejing Yan, Huanhuan Zhang, Yanyin Song, Yuan Chang, Kunyu Liu, Shaoying Zhang, Meilin Cui
Summary: In this study, the effects of a composite coating of chitosan and curdlan on the storage characteristics of postharvest cherry tomatoes were investigated. The results showed that the cherry tomatoes treated with the composite coating exhibited reduced rottenness, weight loss, respiration rate, ethylene production, and membrane permeability during storage. Additionally, the activities of free radical scavenging enzymes and disease-resistant enzymes were maintained at higher levels, and the chemical compounds and antioxidant activities of the treated cherry tomatoes were enhanced.
Article
Polymer Science
Qiaoqiao Jia, Xinghuan Lin, Yiwen Yang, Bo Duan
Summary: Approximately one-third of the world's food production is wasted or lost annually, with perishable items like fruits and vegetables being the most affected due to their short shelf life. To combat this, a simple food preservation strategy was developed using chitin nanofiber aqueous suspension as the substrate and ferulic acid as the physical crosslinker to create a multifunctional protective coating for fruits. The resulting chitin/FA coating films exhibit excellent mechanical properties, water and oxygen resistance, effectively reducing water loss, delaying ripening, and preventing oxidation and microbial invasion in fresh strawberries and fresh-cut apples, highlighting their potential in food preservation.
JOURNAL OF POLYMER SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Ellen A. Malveira, Tawanny K. B. Aguiar, Nilton A. S. Neto, Renato R. Roma, Maria H. C. Santos, Ana L. E. Santos, Ayrles F. B. Silva, Cleverson D. T. Freitas, Bruno A. M. Rocha, Pedro F. N. Souza, Claudener S. Teixeira
Summary: Lectins, such as DVL, have the ability to bind to carbohydrates and inhibit fungal growth. DVL demonstrates anti-candida activity and multiple mechanisms of action against yeast.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Horticulture
Sadiq Shah, Majid S. Hashmi, Ihsan Mabood Qazi, Yasser Durrani, Ali Sarkhosh, Ibrar Hussain, Jeffrey K. Brecht
Summary: The combined application of 1% chitosan plus 400 mu L L-1 thyme oil was found to be more effective in controlling mango anthracnose and extending shelf life compared to thyme oil alone. This treatment significantly reduced decay occurrence, promoted fruit resistance by enhancing phenolic metabolism, and maintained physicochemical properties, demonstrating its efficacy in controlling the disease. Further commercial testing is needed to validate its effectiveness.
SCIENTIA HORTICULTURAE
(2021)
Article
Food Science & Technology
Thu Hong Tran, Xuan Cuong Le, Thi Ngoc Mai Tran, Ngoc Thuy Trang Nguyen, Bao Ngoc Pham, Duong Vu
Summary: A Nano Se edible coating solution was synthesized using gamma irradiation technique with sodium alginate as a stabilizer, showing antimicrobial activity against fungi and improving the storage quality of strawberries.
Article
Food Science & Technology
Tatenda Gift Kawhena, Umezuruike Linus Opara, Olaniyi Amos Fawole
Summary: The effects of gum arabic coatings combined with lemongrass oil and/or pomegranate peel extract on 'Wonderful' pomegranate fruit were studied. The findings suggest that these coatings can be a beneficial postharvest treatment to reduce weight loss and decay development during cold storage.
Article
Plant Sciences
Yu-Jung Cheng, Ying-Jou Wu, Fang-Wei Lee, Ling-Yi Ou, Chi-Nan Chen, Yu-Ying Chu, Yen-Chou Kuan
Summary: The study found that pomelo extract (PE) and its key constituent d-limonene have inhibitory effects on anthracnose in post-harvest mango. Both in vitro and in vivo experiments showed that PE successfully suppressed the growth of Colletotrichum gloeosporioides. Furthermore, storing PE at temperatures below 5 degrees Celsius helped preserve its active compounds and antifungal activity.
Article
Chemistry, Applied
Camila de Souza Araujo, Daniel Amando Nery, Ana Paula de Oliveira, Raimundo Goncalves De Oliveira-Junior, Larissa Araujo Rolim, Norberto Peporine Lopes, Maria Francilene de Souza Silva, Claudia do O. Pessoa, Raimundo Braz-Filho, Livia Macedo Dutra, Josean Fechine Tavares, Lucas Silva Abreu, Marcelo Sobral da Silva, Jackson Roberto Guedes da Silva Almeida
Summary: A new nor-ent-kaurene diterpene and ten other compounds were isolated from the stems of Annona vepretorum. Their chemical structures were elucidated using spectroscopic methods. The cytotoxic activity of some compounds was evaluated and found to be low.
NATURAL PRODUCT RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Micaelle Oliveira de Luna Freire, Luciana Caroline Paulino do Nascimento, Kataryne Arabe Rima de Oliveira, Alisson Macario de Oliveira, Marcos Dos Santos Lima, Thiago Henrique Napoleao, Joao Henrique da Costa Silva, Claudia Jacques Lagranha, Evandro Leite de Souza, Jose Luiz de Brito Alves
Summary: This study assessed the effects of a mixed formulation containing Limosilactobacillus (L.) fermentum on cardiometabolic parameters, inflammatory markers, short-chain fatty acid fecal contents, and oxidative stress in female rats fed a high-fat diet. The results showed that the formulation could increase beneficial fecal contents, reduce hyperlipidemia and hyperglycemia, improve antioxidant capacity, and decrease inflammation, thus preventing dyslipidemia, inflammation, and oxidative stress.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Chemistry, Applied
Andreza Barbosa Silva Cavalcanti, Mayara Dos Santos Maia, Pedro Thiago Ramalho de Figueiredo, Renata Priscila Barros de Menezes, Alex France Messias Monteiro, Roseana Araujo Ramos Meireles, Gabriela Cristina Soares Rodrigues, Ana Rita Rodrigues de Almeida Silva, Jociano da Silva Lins, Laisa Vilar Cordeiro, Valnes S. Rodrigues Junior, Ana Paula O. T. Castelo Branco, Maria de Fatima Agra, Zoe L. Sessions, Eugene N. Muratov, Luciana Scotti, Marcelo Sobral da Silva, Vicente Carlos de Oliveira Costa, Josean Fechine Tavares, Marcus Tullius Scotti
Summary: Plants of the Hyptidinae subtribe, such as Mesosphaerum sidifolium, have been found to contain bioactive molecules with potential as new drug candidates. In this study, the chemical composition of diterpenes isolated from M. sidifolium was analyzed using NMR spectral data. In silico modeling predicted 48 diterpenes with potential biological activity against Mycobacterium tuberculosis. In vitro testing revealed that four compounds showed antimicrobial activity against M. tuberculosis, with Pomiferin D and 1 exhibiting the strongest effect.
NATURAL PRODUCT RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Rebecca Lustosa Silva de Almeida Luz, Raquel B. M. Almeida, Mara Marcia Sampaio Albuquerque, Amanda Ponce Morais Cerqueira, Josean Fechine Tavares, Marcelo Sobral da Silva, Raimundo Braz Filho, Manoelito C. dos Santos Junior, Alexsandro Branco, Mariana B. Botura
Summary: The bioguided fractionations of Ocotea daphinifolia ethyl acetate active extract yielded a fraction with high inhibitory activity for both AChE and BuChE. Purification of this fraction led to the discovery of two new natural products, 1-beta-D-galactopyranosyl-glycerol-2,3-heptanedionate and its minor derivative 1-beta-D-gulopyranosyl-glycerol-2,3-heptanedionate. Molecular docking studies revealed that both compounds interacted with the catalytic site of both enzymes and showed comparable results to rivastigmine and galantamine. This study provides evidence for the potential of glycosylglycerol from O. daphnifolia as a valuable dual cholinesterases inhibitor.
CHEMICAL BIOLOGY & DRUG DESIGN
(2023)
Article
Food Science & Technology
Evandro L. de Souza, Kataryne A. R. de Oliveira, Maria E. G. de Oliveira
Summary: The development of healthy foods and beverages with minimal synthetic ingredient use has become a trend in the food industry, and products obtained by fermentation with lactic acid bacteria (LAB) have been highly accepted by consumers. LAB produces metabolites that can improve various parameters of fermented foods, including dairy, bakery, meat, fruit, and vegetables. These metabolites, such as H2O2, organic acids, fatty acids, amino acids, exopolysaccharides, bacteriocins, acetoin, and acetaldehyde, have been characterized as valuable tools to enhance the physical, chemical, sensory, and functional properties of foods and beverages. Further research on the metabolic pathways and characteristics of LAB should be conducted to optimize their use in the food industry.
CURRENT OPINION IN FOOD SCIENCE
(2023)
Article
Chemistry, Applied
Emilly J. S. P. de Lima, Weider H. P. Paz, Nallarett M. Davila Cardozo, Ana Paula A. Boleti, Patricia Souza e Silva, Lincoln T. H. Mukoyama, Felipe M. A. da Silva, Emmanoel V. V. Costa, Josean F. F. Tavares, Ludovico Migliolo, Hector H. F. Koolen
Summary: In this study, the fruit extract of Xylopia benthamii was analyzed using LC-MS/MS, resulting in the identification of 7 alkaloids and 13 diterpenes. Two kaurane diterpenes were isolated from the extract and their structures were confirmed using spectroscopy and mass spectrometry. Compound 11 showed inhibitory effects on bacterial biofilm formation and strong anti-inflammatory activity in BV-2 cells. These findings suggest that compound 11 has potential for the treatment of neuroinflammatory diseases.
NATURAL PRODUCT RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Zeca M. Salimo, Michael N. Yakubu, Emanuelle L. da Silva, Anne C. G. de Almeida, Yury O. Chaves, Emmanoel V. Costa, Felipe M. A. da Silva, Josean F. Tavares, Wuelton M. Monteiro, Gisely C. de Melo, Hector H. F. Koolen
Summary: Bergenin, a glycosidic derivative of trihydroxybenzoic acid, was first discovered in the rhizomes of Bergenia crassifolia. It has aroused interest due to its antioxidant and anti-inflammatory activities, as well as its potential in various other pharmacological activities. Bergenin is widely distributed in many plant species and its derivatives and extracts have been extensively studied, showing no cytotoxicity on healthy cells.
Article
Plant Sciences
Carla de Fatima Alves Nonato, Emerson Vinicius Silva de Melo, Cicera Janaine Camilo, Maria Kueirislene Amancio Ferreira, Jane Eire Alencar de Meneses, Antonio Wlisses da Silva, Helcio Silva dos Santos, Jaime Ribeiro-Filho, Joanda Paolla Raimundo e Silva, Josean Fechine Tavares, Irwin Rose Alencar de Menezes, Henrique Douglas Melo Coutinho, Grazyna Kowalska, Tomasz Baj, Radoslaw Kowalski, Jose Galberto Martins da Costa
Summary: This study evaluated the antibacterial and anxiolytic effects of essential oils and ethanolic extracts from three species of Lippia (L. alba, L. sidoides, and L. gracilis). The extracts showed significant antibacterial activity, especially those from L. sidoides, and L. alba extract presented the most significant antibiotic-enhancing effect. Additionally, the extracts exhibited anxiolytic effects through modulation of the GABA(A) and 5-HT receptors. These findings provide new pharmacological evidence for potential therapeutic approaches and food preservation using Lippia species.
Article
Biochemistry & Molecular Biology
Ana Luiza de Oliveira Lopes, Camyla Caroliny Neves de Andrade, Samia Sousa Duarte, Karinne Kelly Gadelha Marques, Ramon Ramos Marques de Souza, Fatima de Lourdes Assuncao Araujo de Azevedo, Josean Fechine Tavares, Socrates dos Santos Golzio, Juan Carlos Ramos Goncalves, Marianna Vieira Sobral
Summary: This study evaluated the cytotoxic activity of essential oils extracted from the leaves of Lippia microphylla against several human cancer cell lines. The results showed that the essential oil exhibited anti-melanoma activity and antioxidant effects.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Chemistry, Applied
Joanda Paolla Raimundo e Silva, Priscilla Guimaraes Silva Vasconcelos, Leticia Targino Campos, Juliana de Medeiros Gomes, Manoel Tolentino Leite Filho, Renata Priscila Barros de Menezes, Marcus Tullius Scotti, Josean Fechine Tavares, Andrea Cristina Barbosa Silva, Edja Maria Melo de Brito Costa
Summary: This study analysed the phytochemical profile of Acmella oleracea extract and explored the molecular interactions between its main compounds and target receptors TRPV1 and CB2 in the pathogenesis of Burning Mouth Syndrome (BMS). The results revealed the presence of nine alkylamides and phenolic compounds in A. oleracea extract, and a significant increase in spilanthol content after activated charcoal treatment. Molecular docking studies suggested that alkylamides may act as partial agonists of TRPV1 and CB2, indicating their potential in symptomatic management of BMS.
NATURAL PRODUCT RESEARCH
(2023)
Article
Biochemical Research Methods
Cesar Augusto Goncalves Dantas, Lucas Silva Abreu, Vinicius Ferreira Viana, Carlos Arthur Gouveia Veloso, Maria de Fatima Agra, Marcelo Sobral da Silva, Josean Fechine Tavares
Summary: This study describes the tropane alkaloids in Erythroxylum species and demonstrates the efficiency and importance of using guided isolation methods in natural product research. The results contribute to the phytochemical knowledge of the genus Erythroxylum.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2023)
Article
Biochemistry & Molecular Biology
Maria Helena Araujo de Vasconcelos, Renata Leite Tavares, Maria Leticia da Veiga Dutra, Kamila Sabino Batista, Aline Barbosa D'Oliveira, Rafael Oliveira Pinheiro, Ramon de Alencar Pereira, Marcos dos Santos Lima, Mirian Graciela da Silva Stiebbe Salvadori, Evandro Leite de Souza, Marciane Magnani, Adriano Francisco Alves, Jailane de Souza Aquino
Summary: The present study evaluated the effect of E-VCO on neurobehavior and intestinal health parameters in obesity-induced rats. E-VCO reduced energy intake and body weight gain, showed antidepressant effect, increased lactic acid bacteria counts, modulated organic acids, and protected the hippocampus from neuronal degeneration. Furthermore, it decreased M1 macrophage and increased M2 macrophage population in the gut, improving gut health. These results suggest that E-VCO has promising effects against obesity-related comorbidities.
Article
Multidisciplinary Sciences
Kamila S. Batista, Hassler Clementino Cavalcante, Jessyca A. De Sousa Gomes, Laiane A. Da Silva, Natalia S. De Holanda Cavalcanti, Estefania F. Garcia, Francisca Nayara D. d. Menezes, Tamires A. S. De Lima, Evandro L. De Souza, Marciane Magnani, Jailane De Souza Aquino
Summary: The effects of supplementation with acerola, cashew and guava processing by-products on retinol level, lipid profile, and intestinal function in rats were investigated. The results showed that these fruit by-products have bioactive compounds that promote health, with potential hypolipidemic effects and modulation of intestinal function. These findings have important implications for sustainable agriculture and future clinical studies.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2023)
Article
Biotechnology & Applied Microbiology
Maiara da Costa Lima, Marciane Magnani, Marcos dos Santos Lima, Dumitru Macarisin, Cristina Paiva de Sousa, J. Daniel Dubreuil, Evandro Leite de Souza
Summary: This study evaluated the effects of phenolic-rich extract from jabuticaba depulping waste on enterotoxigenic Escherichia coli (ETEC) strains. The extract exhibited antibacterial activity, reduced cell counts of ETEC, decreased biofilm formation and motility, increased antibiotic susceptibility, and impaired cellular functions of ETEC cells. These findings suggest that the extract could be a potential solution for preventing and treating ETEC infections.
LETTERS IN APPLIED MICROBIOLOGY
(2023)
Article
Food Science & Technology
Julia Vitoria Barbosa Dias, Whyara Karoline Almeida Costa, Dirceu de Sousa Melo, Kataryne Arabe Rima de Oliveira, Andre Ulisses Dantas Batista, Evandro L. de Souza, Rosane Freitas Schwan, Tatiana Colombo Pimentel, Marciane Magnani
Summary: This study assessed the effects of sodium alginate edible coatings added with Lacticaseibacillus casei and/or fructooligosaccharides on the quality of minimally processed mango and melon. The coatings were found to delay the increase in sugar content and pH, decrease in organic acids, and improve firmness, suggesting their potential in extending the shelf life.
