Article
Food Science & Technology
Huan-Yu Lin, Jiunn-Wang Liao, Ruo-Shiuan Chen, Chia-Hua Chang, Hui-Wen Chang, Shih-Chieh Chang, Wen-Shen Chu, Chien-Ku Lin, Hsin-Tang Lin
Summary: The 90-day study concludes that commercial GM soybeans are substantially equivalent to non-GM soybeans in rats, showing no adverse biological effects on body weight, organ weight, or histopathological lesions.
Article
Biotechnology & Applied Microbiology
Joshua G. Philips, Elena Martin-Avila, Andrea V. Robold
Summary: This review provides updated evidence on the likelihood, factors, and barriers for horizontal gene transfer in genetically modified plants, and presents the legislation and frameworks followed by the Australian Gene Technology Regulator in considering the risks posed by horizontal gene transfer.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Review
Environmental Sciences
Chen Shen, Xiang-Chang Yin, Bo-Yang Jiao, Jing Li, Peng Jia, Xiao-Wen Zhang, Xue-Hao Cheng, Jian-Xin Ren, Hui-Di Lan, Wen-Bin Hou, Min Fang, Xun Li, Yu-Tong Fei, Nicola Robinson, Jian-Ping Liu
Summary: A systematic review on the safety of genetically modified (GM) food consumption found serious adverse events in some animal studies, and only minor illnesses in a human trial. There were no significant differences in adverse event reporting rates between different funding sources, suggesting the need for more human clinical trials and long-term cohort studies in this area.
ENVIRONMENTAL SCIENCES EUROPE
(2022)
Article
Food Science & Technology
Morteza Akbari, Zahra Fozouni Ardekani, Giovanni Pino, Naser Valizadeh, Mostafa Karbasioun, Hamid Padash
Summary: Although GM food production is seen as a crucial strategy to meet global food demands, many consumers express doubts about purchasing and consuming GM foods. However, consumers have varying opinions regarding the impact of GM foods on human health and the environment. The present study focuses on Iranian consumers and investigates their concerns, trust, and perception of GM food producer CSR as determinants of their attitudes towards GM food.
Editorial Material
Hematology
Marcela Maus
Summary: Genetically modified immune effector cells (IECs) hold promise as a new type of therapeutic for hematologic malignancies, but their potential to increase the risk of secondary cancers is unclear. This study found no increased risk of secondary cancers in over 1000 patient-years of follow-up across multiple clinical trials of genetically modified IECs for cancer.
Article
Communication
Yuan Wang
Summary: This study reveals that, in a social media context, corrective messages from expert sources and receiving high social endorsements can enhance the effectiveness of misinformation correction and counteract the influence of misinformation. Participants tend to evaluate information in a biased way that aligns with their preexisting beliefs about GM food safety, but their initial misperceptions can be reduced when they receive corrective messages.
SCIENCE COMMUNICATION
(2021)
Article
Forestry
Paulo Henrique Muller da Silva, Othon Silva Abrahao
Summary: The study investigated gene flow from genetically modified eucalyptus trees by measuring pollen dispersal at various distances, concluding that the majority of gene flow occurred at short distances and almost disappeared beyond 300 meters.
Article
Social Sciences, Interdisciplinary
Muhammad Adzran Che Mustapa, Ahmad Firdhaus Arham, Latifah Amin, Hasrizul Hashim
Summary: The study on Malaysian stakeholders revealed their positive attitudes towards GM rice, perceiving it to have moderate benefits and risks, as well as neutral views on moral and religious acceptance. The research also showed significant differences in attitudes across stakeholder groups, educational levels, and age groups, providing insights for scientists and government regulators on the impact of sociodemographic factors on attitudes towards GM rice in Malaysia.
Article
Environmental Sciences
Andre Felipe Lohn, Miluse Trtikova, Ignacio Chapela, Rosa Binimelis, Angelika Hilbeck
Summary: The study demonstrated the possibility of hybridization between GM maize and weedy Spanish teosinte, with stable expression of cry1Ab transgene in all crosses and backgrounds. The Cry1Ab protein showed consistent toxicity on target insect pests in teosinte hybrids, but no strong correlations were observed between transgene transcription levels and Cry1Ab concentrations, nor between Cry1Ab concentrations and insect mortality rates.
ENVIRONMENTAL SCIENCES EUROPE
(2021)
Article
Food Science & Technology
Ewen Mullins, Jean-Louis Bresson, Tamas Dalmay, Ian Crawford Dewhurst, Michelle M. Epstein, Leslie George Firbank, Philippe Guerche, Jan Hejatko, Francisco Javier Moreno, Hanspeter Naegeli, Fabien Nogue, Nils Rostoks, Jose Juan Sanchez Serrano, Giovanni Savoini, Eve Veromann, Fabio Veronesi, Antonio Fernandez Dumont, Michele Ardizzone
Summary: EFSA conducts risk assessment of genetically modified plants for food and feed uses under Regulation (EU) No 503/2013. Estimating animal dietary exposure to newly expressed proteins is vital for the risk assessment of genetically modified feeds. This statement provides guidance on reporting the information applicants need to provide on animal dietary exposure, including proper feed consumption and concentration data, and also presents an Excel calculator for consistent presentation of exposure estimates.
Article
Chemistry, Multidisciplinary
Angelo Vega Rodriguez, Cristina Rodriguez-Oramas, Esther Sanjuan Velazquez, Arturo Hardisson de la Torre, Carmen Rubio Armendariz, Conrado Carrascosa Iruzubieta
Summary: The development and consumption of genetically modified (GM) crops are controversial, but scientific evidence has shown no harm from their use and instead reported multiple benefits. Further research is needed to address concerns about long-term implications of GM crops. Legislation and policies regarding labeling standards for GM products are being discussed.
APPLIED SCIENCES-BASEL
(2022)
Article
Zoology
Colton Kessenich, Andre Silvanovich
Summary: Bioinformatic analyses of protein sequences are crucial for the discovery and safety assessment of insect control proteins in GM crops. The rapid adoption of high throughput sequencing methods has led to a dramatic increase in protein sequences in public databases, providing a rich foundation for new source organisms and proteins. However, automated pipelines can sometimes complicate regulatory safety assessments due to issues with annotation and metadata.
JOURNAL OF INVERTEBRATE PATHOLOGY
(2021)
Article
Environmental Sciences
Gabrielle Cristina dos Santos Goncalves Nascimento, Daniela Giovana da Cunha Barros, Lizandra Souza Ratuchinski, Caio Okon, Patricia Aline Bressiani, Diego Espirito Santo, Charla Chaionara Schults Duarte, Paulo Michel Pinheiro Ferreira, Osvaldo Valarini Valarini Junior, Juan Carlos Pokrywiecki, Elisangela Dusman, Regiane da Silva Gonzalez, Debora Cristina de Souza, Ana Paula Peron
Summary: Octocrylene, a compound commonly found in sunscreen, has potential phytotoxicity and oxidative stress effects on plants and soil animals. It negatively affects seed germination and root growth in some plant species and impairs their defense systems against oxidative damage. In soil animals, octocrylene increases oxidative stress and lipid peroxidation in their cells. Therefore, regulation of octocrylene release into the environment is urgently needed.
WATER AIR AND SOIL POLLUTION
(2023)
Article
Agronomy
Yan Long, Wentao Xu, Caiyue Liu, Mei Dong, Weixiao Liu, Xinwu Pei, Liang Li, Rui Chen, Wujun Jin
Summary: Genetically modified soybeans provide abundant food, but there are concerns about their safety. This study analyzed the gene expression differences in soybean tissues between GM and non-GM varieties and found that there were no massive differences on the transcriptomic level between transgenic and natural soybeans.
GM CROPS & FOOD-BIOTECHNOLOGY IN AGRICULTURE AND THE FOOD CHAIN
(2023)
Article
Agriculture, Multidisciplinary
Nour Chiab, Nissaf Aoiadni, Oumema Nouri-Ellouz, Fatma Ghorbel-Koubaa, Manel Mellouli, Tahya Sellami-Boudawara, Chomous Kallel, Fatma Makni-Ayadi, Radhia Gargouri-Bouzid
Summary: No significant adverse effects on the overall health of rats were observed during the 30-day feeding study of genetically modified potatoes.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Environmental Sciences
Cecilia Nwadiuto Amadi, Beatrice Bocca, Flavia Ruggieri, Anthonett N. Ezejiofor, Glad Uzah, Jose L. Domingo, Joaquim Rovira, Chiara Frazzoli, Orish E. Orisakwe
Summary: The contamination profile and human health risk assessment of various heavy metals in oils and butters purchased from the Nigerian market were evaluated. The study found that some samples exceeded the maximum levels for cadmium and lead, which should be a concern for human health protection.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Joaquim Rovira, Maria Angeles Martinez, Montse Mari, Sara Cristina Cunha, Jose Oliveira Fernandes, Isa Marmelo, Antonio Marques, Line Smastuen Haug, Cathrine Thomsen, Marti Nadal, Jose L. Domingo, Marta Schuhmacher
Summary: Breastfeeding is beneficial for both infants and mothers, but breast milk can contain environmental pollutants. This study measured the levels of various pollutants in the breast milk of Spanish nursing mothers and found correlations between some pollutants and maternal characteristics and smoking. Higher levels of pollutants were detected in samples from primiparous mothers and low-income mothers.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Marta Herrero, Neus Gonzalez, Joaquim Rovira, Montse Marques, Jose Domingo, Marti Nadal
Summary: The study found that formaldehyde is present in some eco-friendly clothing, and the levels are higher than in conventional clothing. However, the formaldehyde levels were still below the legal limits, and the health risks were within acceptable ranges. It is important to note that clothing may contain other toxic substances, and washing clothing before use is a safe practice.
Article
Food Science & Technology
Judit Biosca-Brull, Laia Guardia-Escote, Jordi Blanco, Pia Basaure, Maria Cabre, Fernando Sanchez-Santed, Jose L. Domingo, Maria Teresa Colomina
Summary: The balance of excitatory and inhibitory neurotransmitters is crucial for brain development. This study found that pesticide exposure, particularly to chlorpyrifos (CPF), is associated with neurodevelopmental disorders. Mouse experiments showed that prenatal CPF exposure affected social behavior in male mice, while the GABA system was activated in females. These findings suggest that prenatal CPF exposure has a stronger impact on males and may contribute to sex differences observed in autism spectrum disorder (ASD).
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Food Science & Technology
Montse Marques, Marti Nadal, Jose L. Domingo
Summary: Polybrominated diphenyl ethers (PBDEs) are a type of brominated flame-retardants (BFRs) that are mainly introduced to the human body through dietary intake. This review discusses recent studies conducted from 2012 to 2022, which show a general trend of decreasing levels of PBDEs in food and consequently, a decrease in dietary intake. The lack of tolerable daily intakes of PBDEs remains a challenge for assessing the human health risks associated with these compounds.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Environmental Sciences
Avelino Nunez-Delgado, Warish Ahmed, Jesus L. Romande, Kuldeep Dhama, Jose L. Domingo
Summary: This article introduces a virtual special issue on the origin of the SARS-CoV-2 virus, aiming to shed light on the matter through high-quality scientific research papers. The special issue received 50 submissions, and the most outstanding papers were accepted for publication after careful peer-review. The editors believe that these papers provide valuable contributions to the scientific community and society.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Marta Herrero, Joaquim Rovira, Neus Gonzalez, Montse Marques, Fernando Barbosa, Jordi Sierra, Jose L. Domingo, Marti Nadal, Marilia Cristina Oliveira Souza
Summary: The interest in determining the chemical composition of textile products has increased due to toxicological issues and environmental concerns. This study analyzed the levels of twenty trace elements in clothing items commercialized in Spain and evaluated the potential health implication of dermal exposure in early life. Aluminum, zinc, and titanium showed the highest concentrations, while chromium was found in high levels in black polyester. Dermal exposure to titanium was associated with a hazard quotient higher than the threshold value, indicating potential risks for pregnant women and newborns.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Marilia Cristina Oliveira Souza, Neus Gonzalez, Marta Herrero, Montse Marques, Joaquim Rovira, Marti Nadal, Fernando Barbosa, Jose Luis Domingo
Summary: This study investigated the concentrations of harmful substances in clothing sold in Brazil and Spain, finding higher levels in Brazil due to the lack of regulation. Some substances exceeded health thresholds. Continuous studies are recommended to determine the co-occurrence of carcinogenic substances.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Judit Biosca-Brull, Laia Guardia-Escote, Pia Basaure, Maria Cabre, Jordi Blanco, Cristian Perez-Fernandez, Fernando Sanchez-Santed, Jose L. Domingo, Maria Teresa Colomina
Summary: This study aimed to evaluate the effects of prenatal chlorpyrifos (CPF) exposure and APOE genotype on social behavior and its relation to changes in GABAergic and glutamatergic systems. Results showed that prenatal CPF exposure impaired social novelty preference and increased the expression of GABA-A alpha 1 subunit in females of both genotypes. Additionally, the expression of GAD1, KCC2, and GABA-A alpha 2 and alpha 5 subunits were increased in apoE3 mice, while CPF treatment only accentuated the expression of GAD1 and KCC2. However, further research is needed to evaluate the functional relevance of the detected influences in the GABAergic system in adult and old mice.
ENVIRONMENTAL RESEARCH
(2023)
Review
Genetics & Heredity
David Mateo, Montse Marques, Jose L. Domingo, Margarita Torrente
Summary: Dementia is a major public health challenge due to its high socio-economic impact and difficulties in diagnosis and treatment. The relationship between gut microbiota and neurocognitive disorders, including dementia, has gained significant interest. Studies have reported associations between gut microbiota dysbiosis and certain types of dementia, such as Alzheimer's disease and Parkinson's disease dementia. Probiotics have shown potential to restore dysbiosis and improve neurocognitive symptoms in these dementias. However, further research is needed to clarify the controversial results.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
(2023)
Review
Environmental Sciences
Marilia Cristina Oliveira Souza, Jonas Carneiro Cruz, Cibele Aparecida Cesila, Neus Gonzalez, Bruno Alves Rocha, Joseph A. Adeyemi, Marti Nadal, Jose L. Domingo, Fernando Barbosa
Summary: Due to population growth, agricultural practices have exponentially increased to meet the demand for food. However, this increase has led to the widespread use of pesticides, causing environmental pollution and posing risks to human health. In Brazil, where agriculture is vital to the economy, the approval and regulation of pesticide use is inconsistent and flawed compared to other countries. This paper critically reviews the risks and benefits of pesticide use in agriculture and highlights the need for improved legislation and alternative solutions to reduce pesticide levels in the environment.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Joseph A. Adeyemi, Jonas C. Cruz, Tolulope Ayo-Awe, Bruno A. Rocha, Chris O. Adedire, Vanessa C. de Oliveira-Souza, Marilia Cristina Oliveira Souza, Jose L. Domingo, Fernando Barbosa Jr
Summary: This study investigated the concentrations of trace elements in print paper products and assessed their potential impact on human health through dermal exposure. The results revealed that the levels of trace elements were low and did not pose significant toxic risks to humans.
ENVIRONMENTAL RESEARCH
(2023)
Article
Food Science & Technology
Neus Gonzalez, Carla Pamies, Paula Martinez, Laura Marti, Jose L. Domingo, Marti Nadal, Montse Marques
Summary: Pesticides are organic compounds used in agriculture to control weeds and insect infestations. Consuming these compounds through diet can have serious health effects. A study found that an organic dietary intervention reduced levels of urinary dialkyl phosphates (DAP) and confirmed lower pesticide levels in organic food compared to conventional food.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Environmental Sciences
Marilia Cristina Oliveira Souza, Neus Gonzalez, Marta Herrero, Montse Marques, Joaquim Rovira, Jose L. Domingo, Fernando Barbosa Jr, Marti Nadal
Summary: The presence of a large number of chemicals in clothing and their harmful effects on human health and the environment have gained global attention. Azo dyes, widely used in the textile industry, are now considered emerging pollutants of great concern due to their potential health hazards. This study evaluated the levels of non-regulated aromatic amines (AAs) in clothing items from Spain and Brazil and assessed the potential impact on the health of vulnerable populations. The results showed the presence of AAs in clothes from both countries, with some concentrations exceeding safety thresholds, indicating possible risks to human health.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Environmental Sciences
Ana Carolina Cavalheiro Paulelli, Jonas Carneiro Cruz, Bruno Alves Rocha, Marilia Cristina Oliveira Souza, Silvana Ruella de Oliveira, Cibele Aparecida Cesila, Paula Picoli Devoz, Walter dos Reis Pedreira Filho, Monica Soares de Campos, Jose L. Domingo, Fernando Barbosa
Summary: This study investigated the association between toxic metals/metalloids and the biomarker 8OHdG in individuals affected by the Fundão dam failure in Brazil. The results showed that high exposure to toxic metals/metalloids might increase 8OHdG levels, potentially leading to adverse health effects. Further studies are needed to monitor exposure levels and explore additional health impacts.
ENVIRONMENTAL RESEARCH
(2023)