Necrostatin-1 Supplementation to Islet Tissue Culture Enhances the In-Vitro Development and Graft Function of Young Porcine Islets

The effects of necrostatin‐1 on the in vitro development and function of young porcine islets over 14‐day prolonged tissue culture

(2021) Hien Lau et al.   XENOTRANSPLANTATION

Long-term metabolic consequences of acute dioxin exposure differ between male and female mice

(2020) Myriam P. Hoyeck et al.   Scientific Reports

An islet maturation media to improve the development of young porcine islets during in vitro culture

(2020) Hien Lau et al.   Islets

Dose-dependent effects of necrostatin-1 supplementation to tissue culture media of young porcine islets

(2020) Hien Lau et al.   PLoS One

Glucagon receptor antagonism increases mouse pancreatic δ-cell mass through cell proliferation and duct-derived neogenesis

(2019) Liangbiao Gu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cost and Scalability Analysis of Porcine Islet Isolation for Islet Transplantation: Comparison of Juvenile, Neonatal and Adult Pigs

(2019) Rachel Vanderschelden et al.   CELL TRANSPLANTATION

Necrostatin‐1 supplementation enhances young porcine islet maturation and in vitro function

(2019) Hien Lau et al.   XENOTRANSPLANTATION

Evidence of necroptosis in osteoarthritic disease: investigation of blunt mechanical impact as possible trigger in regulated necrosis

(2019) Jana Riegger et al.   Cell Death & Disease

Regulated Cell Death Seen through the Lens of Islet Transplantation

(2018) Antonio Bruni et al.   CELL TRANSPLANTATION

Divergent antioxidant capacity of human islet cell subsets: A potential cause of beta-cell vulnerability in diabetes and islet transplantation

(2018) Atsushi Miki et al.   PLoS One

Functional maturation and in vitro differentiation of neonatal porcine islet grafts

(2018) Tarek Hassouna et al.   TRANSPLANTATION

Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability

(2018) A. K. J. Gradel et al.   Journal of Diabetes Research

Beta cell dedifferentiation in T2D patients with adequate glucose control and non-diabetic chronic pancreatitis

(2018) Jiajun Sun et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

In vitro characterization of neonatal, juvenile, and adult porcine islet oxygen demand, β-cell function, and transcriptomes

(2018) Kate E. Smith et al.   XENOTRANSPLANTATION

Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling

(2017) Chunhua Dai et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of Inflammation in β-cell Dedifferentiation

(2017) Thierry M. Nordmann et al.   Scientific Reports

Necrostatin-1 rescues mice from lethal irradiation

(2016) Zhentai Huang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Necrostatin-1 protection of dopaminergic neurons

(2015) Yan-bo Cheng et al.   Neural Regeneration Research

Long-term cultured neonatal islet cell clusters demonstrate better outcomes for reversal of diabetes: in vivo and molecular profiles

(2015) Elvira Jimenez-Vera et al.   XENOTRANSPLANTATION

Current status of islet xenotransplantation

(2015) Chung-Gyu Park et al.   International Journal of Surgery

DAMP production by human islets under low oxygen and nutrients in the presence or absence of an immunoisolating-capsule and necrostatin-1

(2015) Genaro A. Paredes-Juarez et al.   Scientific Reports

Dimethyl Fumarate Ameliorates Acute Pancreatitis in Rodent

(2014) Lourdes Robles et al.   PANCREAS

Receptor-interacting protein kinases modulate noise-induced sensory hair cell death

(2014) H-W Zheng et al.   Cell Death & Disease

Prospectively Isolated NGN3-Expressing Progenitors From Human Embryonic Stem Cells Give Rise to Pancreatic Endocrine Cells

(2014) Qing Cai et al.   Stem Cells Translational Medicine

In Vitro Maturation of Viable Islets from Partially Digested Young Pig Pancreas

(2013) Morgan Lamb et al.   CELL TRANSPLANTATION

Correlation of Released HMGB1 Levels with the Degree of Islet Damage in Mice and Humans and with the Outcomes of Islet Transplantation in Mice

(2012) Takeshi Itoh et al.   CELL TRANSPLANTATION

Clinical Islet Xenotransplantation: How Close Are We?

(2012) D. J. van der Windt et al.   DIABETES

Strategies toward single-donor islets of Langerhans transplantation

(2011) A.M. James Shapiro   Current Opinion in Organ Transplantation

NO donor induces Nec-1-inhibitable, but RIP1-independent, necrotic cell death in pancreatic β-cells

(2011) Yoshiaki Tamura et al.   FEBS LETTERS

24(S)-Hydroxycholesterol Induces Neuronal Cell Death through Necroptosis, a Form of Programmed Necrosis

(2011) Kazunori Yamanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diabetic rats and mice are resistant to porcine and human insulin: flawed experimental models for testing islet xenografts

(2009) Andrew R. Pepper et al.   XENOTRANSPLANTATION

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology