Review
Biochemistry & Molecular Biology
Jia Ying Brenda Tan, Bo Kyeong Yoon, Nam-Joon Cho, Jasmina Lovric, Mario Jug, Joshua A. Jackman
Summary: The utilization of lipid nanoparticles to deliver fatty acids and monoglycerides for treating medical diseases shows promising potential, with a focus on understanding the relationship between nanoparticle structure and biological function. Opportunities for translation and regulatory needs are discussed, highlighting unmet clinical opportunities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Polymer Science
Mikel Rincon-Iglesias, Manuel Salado, Senentxu Lanceros-Mendez, Erlantz Lizundia
Summary: This work reports on the development of degradable magnetic nanocomposites based on biodegradable polyesters and their tunable mechanical properties and crystallization behavior through the inclusion of Fe3O4 nanoparticles. The research provides new paths for the fabrication of biodegradable magnetic materials and devices, aiming to replace durable conventional systems based on petroleum derived materials.
Article
Engineering, Biomedical
Pratikkumar Patel, John Fetse, Chien -Yu Lin, Yuhan Guo, Md Reaid Hasan, Maryam Nakhjiri, Zhen Zhao, Akshay Jain, Kun Cheng
Summary: The use of siRNA therapeutics for cancer treatment is a promising approach, but delivering siRNAs to tumors is challenging. Recent success in delivering siRNA to the liver has spurred the development of biomaterials for tumor siRNA delivery. Researchers have developed a new class of amino acid-modified lipids for siRNA delivery to cancer cells. These lipids effectively protect siRNA, release it from endosomes, and are taken up by cells more efficiently compared to other lipids. The best lipid (LHHK) demonstrates significant gene silencing activity in prostate and pancreatic cancer cells and inhibits tumor growth in a pancreatic cancer mouse model.
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Multidisciplinary
Woochan Kim, Taeseong Han, Yonghyun Gwon, Sunho Park, Hyoseong Kim, Jangho Kim
Summary: Nanotechnology has enabled the development of active food packaging systems that can improve the preservation of perishable products by controlling moisture evaporation and inhibiting mold generation, overcoming limitations of traditional packaging systems.
Article
Food Science & Technology
Pamela Cuenca, Oscar Albani
Summary: The aim of this study was to demonstrate the effectiveness of biodegradable films activated with natamycin for preserving regional cheeses. Starch and amylose films were prepared using water as a plasticizer and different concentrations of antimicrobial. The films exhibited good mechanical properties and biodegradability, and the addition of natamycin reduced water vapor permeability without compromising their applicability as coatings. Cheese wrapped with the activated films showed no development of molds and yeasts, and weight loss was reduced under high humidity storage conditions. The use of starch films with 10 mg/dm(2) of natamycin delayed the growth of molds, yeasts, and psychrophilic bacteria, providing better-quality food preservation.
FOOD AND BIOPROCESS TECHNOLOGY
(2023)
Article
Chemistry, Physical
Kun Chen, Yifan Li, Zhuolin Du, Sanming Hu, Jianyu Huang, Zhijun Shi, Bin Su, Guang Yang
Summary: Self-powered flexible electromagnetic sensors based on flexible magnets have great potential for application in the wearable field. This study presents a novel flexible, biodegradable, and self-powered electromagnetic sensor prepared using CoFe2O4 embedded magnetic bacterial cellulose. The magnetic CoFe2O4 nanoparticles were synthesized within a network structure of degradable bacterial cellulose for flexible composite magnetic films. The degradation experiment showed that the flexible magnetic films completely degraded within 56 hours, with the remaining CoFe2O4 nanoparticles being recyclable. The flexible electromagnetic sensors based on composite films demonstrated excellent sensing properties and stability in a customized testing platform. Furthermore, an intelligent jacket sewn with flexible magnetic films and copper coils was designed to monitor motion signals and distinguish motion states, highlighting the potential of using biodegradable flexible electromagnetic sensors as eco-friendly wearable sensors.
Article
Multidisciplinary Sciences
Liew Wen Ching, Farah Wahida Mohd Keesan, Ida Idayu Muhamad
Summary: The potential usability of zinc oxide and graphene oxide as mechanical strengthening nanocomposites for food packaging was evaluated. The synergistic effect of zinc oxide and graphene oxide significantly improved the mechanical and antibacterial properties of the composite film.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Cristiane De Carli, Volkan Aylanc, Kheira M. Mouffok, Arantzazu Santamaria-Echart, Filomena Barreiro, Andreia Tomas, Celeide Pereira, Paula Rodrigues, Miguel Vilas-Boas, Soraia I. Falca
Summary: This study developed active films based on chitosan enriched with propolis extract and demonstrated their improved properties, including enhanced thermal stability, mechanical strength, and antimicrobial and antioxidant activities. These films have potential applications in food packaging to extend the shelf life of products due to their eco-friendly nature.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Yating Zhao, Fenglian Chen, Chengcheng Gao, Xiao Feng, Xiaozhi Tang
Summary: The study found that a low content of hsian-tsao can improve the physical properties of quinoa protein films and enhance antioxidant activity. Conversely, a high content of hsian-tsao can lead to cracks in the composite films.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Food Science & Technology
N. S. Said, Nazlin K. Howell, N. M. Sarbon
Summary: This article discusses the potential use of gelatin-based film as active and smart edible films in food packaging. It highlights the advantages of gelatin-based film and its applications in enhancing food safety and promoting healthy lifestyle.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Polymer Science
Paola Scarfato, Maria Luisa Graziano, Arianna Pietrosanto, Luciano Di Maio, Loredana Incarnato
Summary: This study aimed to use hazelnut perisperm as an antioxidant agent in the production of biodegradable polymeric films for active packaging. The results showed that the presence of hazelnut perisperm conferred significant antioxidant activity, extended the sealability temperature range, and decreased the stiffness and mechanical strength of the films while increasing their ductility.
Article
Engineering, Environmental
S. Mohan, T. G. Unnikrishnan, Umang Dubey, M. Ramesh, K. Panneerselvam
Summary: Antimicrobial and biodegradable film-forming biopolymers, such as chitosan combined with Mustard oil, show great potential for applications in food packaging. The inclusion of Mustard oil improves the physical, mechanical, thermal, antibacterial, and antioxidant properties of the film. Additionally, the composite films demonstrate good soil biodegradation, making them environmentally friendly.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Review
Biochemistry & Molecular Biology
Edy Subroto, Robi Andoyo, Rossi Indiarto
Summary: To protect and enhance the absorption and targeting of active compounds, solid lipid nanoparticles (SLNs) are used for encapsulation. Initially used for hydrophobic compounds, SLNs are now widely used for hydrophilic and semipolar compounds. This article provides an overview of the current research on SLNs for encapsulation and delivery of active and antioxidant compounds, including synthesis methods and various applications.
Review
Food Science & Technology
Julia Rabelo Vaz Matheus, Roberta Fontanive Miyahira, Ana Elizabeth Cavalcante Fai
Summary: The production of fruit-film packaging is gaining attention in scientific research due to its environmentally friendly, nontoxic, and edible characteristics. These alternative packaging options help minimize environmental impacts from non-biodegradable plastics and reduce postharvest fruit loss. With antioxidant and antimicrobial compounds, fruit films have potential as functional packages, offering a simpler and more practical solution compared to films made from fruit flour or extracts. Understanding their mechanical properties, bioactive compounds, and applications opens up new possibilities for producing and using these films.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Chemistry, Applied
Yongzhen Lei, Long Mao, Jin Yao, Heping Zhu
Summary: Bioinspired by mussel adhesion behaviors, a catechol-functionalized chitosan (C-CS)/polyvinyl alcohol (PVA) composite film was developed for active food packaging. The composite film showed improved UV, mechanical, antibacterial properties, and remained transparent. This new material has great potential in the field of active packaging.
CARBOHYDRATE POLYMERS
(2021)
Review
Food Science & Technology
Mehran Moradi, Rahim Molaei, Seyedeh Alaleh Kousheh, Jonas T. Guimaraes, David Julian McClements
Summary: Nanotechnology is increasingly being applied to food packaging, with the incorporation of nanoparticles such as carbon dots improving the shelf life and safety of foods. Carbon dots synthesized from environmentally friendly sources have shown potential as additives in food packaging materials, enhancing their mechanical properties and inhibiting the growth of harmful microorganisms. This article reviews recent progress in the synthesis of carbon dots from microorganisms and food by-products, and discusses their potential applications in active and intelligent food packaging materials.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Qianzhu Lin, Shengju Ge, David Julian McClements, Xiaojing Li, Zhengyu Jin, Aiquan Jiao, Jinpeng Wang, Jie Long, Xueming Xu, Chao Qiu
Summary: The improved understanding of the connection between diet and health has led to growing interest in the development of functional foods designed to improve health and wellbeing. Nano-based delivery systems, particularly protein-based nanocarriers, are being developed to incorporate potentially health-promoting bioactive ingredients into these products. This review focuses on the preparation, properties, and applications of protein-based nanocarriers, including their use in targeted delivery and stimulus-responsive release of bioactive ingredients in the food industry.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Yuwan Liu, Chao Qiu, Xiaojing Li, David Julian McClements, Chenxi Wang, Zhiheng Zhang, Aiquan Jiao, Jie Long, Kunfu Zhu, Jinpeng Wang, Zhengyu Jin
Summary: This paper reviews the preparation and properties of several starch-based nanoparticles and cyclodextrins derivatives, focusing on their mechanisms in modulating glucose release and gut microbiome in the gastrointestinal tract. The authors suggest that these edible nanomaterials, through encapsulation and protection of prebiotics or bioactive components, can achieve probiotic functions, providing valuable information for designing functional foods to improve human health.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Marzieh Shakouri, Maryam Salami, Loong-Tak Lim, Mohammad Ekrami, Mehdi Mohammadian, Gholamreza Askari, Zahra Emam-Djomeh, David Julian McClements
Summary: Multifunctional and innovative biopolymer-based indicator films containing gelatin and basil seed gum, with different concentrations of saffron petal extract, were prepared. The addition of saffron petal extract improved the physical properties and antimicrobial activity of the indicator films, making them potential indicators for monitoring food spoilage.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Review
Food Science & Technology
Vaibhav Kumar Maurya, Amita Shakya, Khalid Bashir, Kulsum Jan, David Julian McClements
Summary: This article discusses the challenges and potential solutions for fortifying foods with vitamin D, which has low solubility, stability, and bioavailability. Encapsulating vitamin D within well-designed delivery systems containing nanoscale or microscale particles could overcome these challenges. The concept of fortification by design is introduced, involving a systematic approach to select appropriate vitamin D form, food matrix, delivery system, production method, testing procedures, and system optimization.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Review
Food Science & Technology
Shan Zhang, Yashu Chen, David Julian McClements, Tao Hou, Fang Geng, Peng Chen, Hongjian Chen, Bijun Xie, Zhida Sun, Hu Tang, Yaqiong Pei, Shuang Quan, Xiao Yu, Qianchun Deng
Summary: This paper summarizes and analyzes the limitations and challenges of incorporating whole flaxseed (flour) into fortified food products, as well as its potential influences on food matrix and edibility. The potential influencing mechanisms of flaxseed (flour) on different substrate components are investigated, and possible solutions against negative impacts are proposed. Overall, this paper provides useful information for expanding the application of whole flaxseed (flour) based on optimal edibility and nutritional properties of fortified food products.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Review
Food Science & Technology
Jiayan Zhang, Huan Deng, Juan Bai, Xinghua Zhou, Yansheng Zhao, Ying Zhu, David Julian McClements, Xiang Xiao, Quancai Sun
Summary: This article reviews the nutritional and functional characteristics of barley, focusing on its ability to improve glucose/lipid metabolism. It also discusses recent trends in barley product development and explores current limitations and future research directions in glucolipid modulation mechanisms and barley bioprocessing.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Wenbo Miao, Mengyun Yue, Chao Qiu, Xiaojing Li, Shangyuan Sang, David Julian McClements, Long Chen, Jie Long, Aiquan Jiao, Jinpeng Wang, Zhengyu Jin
Summary: Plant-derived antioxidants (PD-AOs) play a crucial role in food preservation and human health. However, the current limitations of PD-AOs, such as poor chemical stability and water solubility, hinder their application in the food and pharmaceutical industries. This review discusses the use of cyclodextrins (CDs) to overcome these limitations by forming host-guest interactions with PD-AOs, improving their dispersion and stability in food systems, and selectively isolating them from multi-component systems. The CD-antioxidant interactions show great potential in addressing isolation, detection, and food quality issues.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Applied
Zhiheng Zhang, Xiaojing Li, Shangyuan Sang, David Julian McClements, Long Chen, Jie Long, Aiquan Jiao, Zhengyu Jin, Chao Qiu
Summary: In this study, zein/hydroxypropyl-beta-cyclodextrin nanoparticles were successfully synthesized and characterized. These nanoparticles exhibited high encapsulation efficiency for curcumin and improved its antioxidant activity and photostability. They have the potential to be used as effective food-grade delivery systems for low water-soluble bioactive substances.
Review
Materials Science, Multidisciplinary
Arezou Khezerlou, Hajar Zolfaghari, Samira Forghani, Reza Abedi-Firoozjah, Mahmood Alizadeh Sani, Babak Negahdari, Masumeh Jalalvand, Ali Ehsani, David Julian McClements
Summary: This review explores the potential of combining edible coating materials with non-thermal processing technologies to enhance the quality, safety, shelf life, and sustainability of food products. Edible coatings made from food-grade ingredients can provide necessary mechanical and barrier properties, and functional additives can further improve quality and extend shelf life. Non-thermal processing techniques, such as high hydrostatic pressure and pulsed light, can inhibit the growth of pathogens and spoilage microorganisms. This combined approach has been successfully applied to perishable foods. Rating: 8/10.
Article
Chemistry, Applied
Sheliang Zhao, David Julian Mcclements, Xuebo Liu, Fuguo Liu
Summary: The low oral bioavailability of some bioactive ingredients is a challenge in the supplement and functional food areas. This study designs natural carriers that can simultaneously deliver both hydrophobic and hydrophilic bioactive ingredients, thereby increasing their ability to exert synergistic effects.
FOOD HYDROCOLLOIDS
(2024)
Article
Food Science & Technology
Wenhan Xu, Wenzhang Chen, Qiankun Wang, David Julian McClements, Shuai Chen, Yutang Wang, Xuebo Liu, Cheng Wang, Fuguo Liu
Summary: Bio-based packaging materials improve the quality, safety, and shelf life of foods by reducing their interactions with the environment. This study compares the structures and properties of two methods, blending and layer-by-layer deposition, in the preparation of composite packaging materials. The preservation effects on fruits were analyzed, and the blend coatings showed better water vapor barrier properties and good mechanical and EGCG-release properties. Overall, this study helps in designing edible packaging materials for various applications.
Article
Chemistry, Applied
Wenmeng Liu, Long Chen, David Julian Mcclements, Yidong Zou, Guanxiong Chen, Zhengyu Jin
Summary: In this study, a complex of chitosan, betaine, and vanillin was used as a starch modifier to improve the viscosity, gelation, and thermal stability of corn starch. The modification mechanism involved hydrogen bond interaction, Schiff base crosslinking, and electrostatic interaction. The results showed that the complex enhanced the viscosity and viscoelasticity of the starch, promoted gel formation, and improved thermal stability. Additionally, the microstructure of the starch became more orderly and regular with the addition of the modifier.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Zhiheng Zhang, Yaxu Meng, Jinpeng Wang, Chao Qiu, Wenbo Miao, Qianzhu Lin, Xiaojing Li, Shangyuan Sang, David Julian McClements, Aiquan Jiao, Zhengyu Jin
Summary: A simple reverse solvent co-precipitation method was used to prepare zein/debranched oxidized starch coreshell composite nanoparticles, which showed good stability and the ability to protect resveratrol. The nanoparticles had a higher encapsulation rate of resveratrol compared to pure protein nanoparticles. The composite nanoparticles exhibited various interactions and maintained the biological activity of nutrient molecules under different conditions.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Xiaoyan Hu, Qian Ju, Charmaine K. W. Koo, David Julian McClements
Summary: This study successfully created plant-based biopolymer composites with meat-like textures using coacervation and thermal gelation. By modulating the electrostatic interactions between potato protein and gellan gum, and controlling the pH value, the structural organization and rheology of the composites could be controlled. The findings of this study are significant for the design of plant-based foods with desirable textural attributes.
FOOD HYDROCOLLOIDS
(2024)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)