Review
Plant Sciences
Anshika Sethi, Abhishek Bhandawat, Pratap Kumar Pati
Summary: Cytochrome P450 enzymes play a critical role in the biosynthesis of secondary metabolites and show great potential as targets for metabolic pathway engineering. They are found in all life domains and have been successfully utilized in medicinal plants. Pathway engineering has achieved significant improvements in the production of important bioactive compounds, and strategies to overcome limitations associated with CYP engineering are being explored.
Article
Agriculture, Multidisciplinary
Junxiu Wang, Yong Li, Xinwei Wang, Ke Cao, Gengrui Zhu, Weichao Fang, Changwen Chen, Jinlong Wu, Jian Guo, Qiang Xu, Lirong Wang
Summary: This study discovers that Prunus davidiana, a wild relative of cultivated peach, utilizes betulin as a key defensive metabolite to protect against aphid attacks. Betulin exhibits toxic properties towards pests but not beneficial insects. The cytochrome P450 gene PpCYP716A1 is responsible for the synthesis of betulin.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Engineering, Environmental
Toshio Mori, Haruka Ohno, Hirofumi Ichinose, Hirokazu Kawagishi, Hirofumi Hirai
Summary: In this study, it was found that the white-rot fungus P. chrysosporium degrades neonicotinoid insecticides through the activity of at least two different CYP isozymes.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Review
Chemistry, Inorganic & Nuclear
Jingjing Wu, Xiaoqing Guan, Ziru Dai, Rongjing He, Xinxin Ding, Ling Yang, Guangbo Ge
Summary: This article summarizes the recent progress in the development and applications of molecular probes for human CYPs, including their structural and catalytic features, design principles, and strategies. It provides comprehensive lists of molecular probes for various human CYP enzymes, along with their structural information and kinetic parameters, while discussing current challenges and future perspectives in the field.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Microbiology
James B. Y. H. Behrendorff
Summary: Cytochrome P450 enzymes, known for their ability to insert oxygen into a wide range of substrates, can also perform reductive reactions under hypoxic conditions, contributing to the dehalogenation and denitration of environmental pollutants. This enzyme activity, first discovered in human pharmacology, has been observed in various organisms.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Pharmacology & Pharmacy
Daiqiao Ai, Hanxuan Cai, Jiajia Wei, Duancheng Zhao, Yihao Chen, Ling Wang
Summary: Cytochrome P450 (CYP) is a superfamily of oxidizing enzymes involved in the metabolism of various compounds. In this study, a deep learning method called FP-GNN was used to develop classification models for predicting the inhibitory activity of molecules against five CYP isoforms. The evaluation results showed that the multi-task FP-GNN model achieved the best predictive performance compared to other existing models. The developed online webserver DEEPCYPs can be used to detect potential inhibitory activity of compounds against CYPs, aiding in drug-drug interaction prediction and early-stage drug discovery.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Engineering, Environmental
Shengnan Li, Yuhao Chu, Nanqi Ren, Shih-Hsin Ho
Summary: This review provides a concise summary of microalgal P450 diversity and the critical factors affecting their expression and function, focusing on the biotransformation of PPCPs. Current studies on PPCPs have mainly focused on laboratory experiments and environmental investigations. Various techniques, including protein engineering and metabolic engineering, have been recommended to meet different application needs.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Katsutoshi Ito, Takeshi Hano, Mana Ito, Toshimitsu Onduka, Nobuyuki Ohkubo, Kazuhiko Mochida
Summary: This study focuses on bioremediation using marine benthic animals and finds that Thalassodrilides cf. briani can decompose polycyclic aromatic hydrocarbons in contaminated sediments. Transcriptomic and metabolomic analyses reveal that the organism adapts to the polluted environment by regulating its metabolism.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Mlamuli Ndabambi, Ki Yong Kim, Jee-Hyun Jung, Un-Hyuk Yim, Jeong-Eun Oh
Summary: The study investigated the biotransformation and tissue distribution of methylated phenanthrenes in black rockfish, and identified these compounds as potential biomarkers of rockfish exposure to petrogenic PAHs that can be effectively eliminated from the fish's body.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Chemistry, Organic
Karan Malhotra, Jakob Franke
Summary: This review provides a comprehensive overview of 149 functionally characterised CYP enzymes involved in the biosynthesis of triterpenoids and steroids in plants. It describes their phylogenetic distribution, reaction mechanisms, and highlights recent advancements in the field.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Plant Sciences
Hongsheng Gao, Huiqing Huang, Kaifeng Lu, Cuiting Wang, Xiaohua Liu, Zhizhong Song, Houjun Zhou, Lei Yang, Bei Li, Chunyan Yu, Hongxia Zhang
Summary: The expression of OsCYP714D1 gene improved salt tolerance in transgenic poplar plants by regulating gibberellin and ion homeostasis, resulting in increased plant height, K+ content, and decreased growth inhibition and Na+ content under high salt stress conditions. Transcriptomic analyses revealed up-regulation of GA biosynthesis, signaling, and stress responsive genes in transgenic plants, while gene ontology analyses indicated enrichment of genes involved in plant hormone and ion metabolic activities in the transgenic plants. OsCYP714D1 can be used as a candidate gene for engineering new tree varieties with improved biomass production and salt stress resistance.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Environmental Sciences
Shuqi Lin, Jinchao Wei, Bentao Yang, Meng Zhang, Rui Zhuo
Summary: This paper reviews the role of white rot fungal CYP450 in the biodegradation of organic pollutants, focusing on inhibitory experiments and direct/indirect evidence. It also discusses the catalytic mechanisms of white rot fungal CYP450, its application potential, and future prospects for bioremediation.
Article
Biochemistry & Molecular Biology
Monika Heyer, Sandra S. Scholz, Michael Reichelt, Grit Kunert, Ralf Oelmueller, Axel Mithoefer
Summary: CML37 and CML42 play antagonistic roles in regulating plant responses to stress by altering phytohormone signaling pathways, highlighting their importance in balancing and fine-tuning plant reactions to environmental stress.
PLANT MOLECULAR BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Didem Yildirim, Cem Ozic, Yunus Ensari
Summary: The first P450 enzyme from Azorhizobium caulinodans was identified and expressed, showing enhanced expression in E.coli when incubated at 25 degrees C for 24 hours in TB media supplemented with 0.75 mM IPTG, 0.5 mM ALA, and 0.75 mM FeCl3. The purified enzyme exhibited a broad substrate spectrum and optimal activity at pH 6.0 and 40 degrees C, suggesting its potential for industrial applications.
Review
Entomology
Ralf Nauen, Chris Bass, Rene Feyereisen, John Vontas
Summary: Insect cytochrome P450 monooxygenases (P450s) play important physiological roles and are particularly involved in the detoxification of xenobiotics. Recent advances in insect genomics and functional approaches have shed light on the evolution of insect P450s, their regulation mechanisms, and the genetic alterations leading to insecticide resistance. Additionally, studies on the sensitivity of beneficial insects to insecticides have provided valuable knowledge for managing P450-mediated resistance and safeguarding their health.
ANNUAL REVIEW OF ENTOMOLOGY
(2022)
Article
Engineering, Civil
Peng Xu, Ke Wang, Mohammad Mehedi Hassan, Chien-Ming Chen, Weiguo Lin, Md Rafiul Hassan, Giancarlo Fortino
Summary: This paper employs a One-Shot Neural Architecture Search (NAS) to generate derivative models with different scales and studies the relationship between network sizes and model robustness. The experimental results show that reducing model parameters can increase model robustness under maximum adversarial attacks, while increasing model parameters can enhance model robustness under minimum adversarial attacks. This analysis helps to understand the adversarial robustness of models with different scales for edge AI transportation systems.
IEEE TRANSACTIONS ON INTELLIGENT TRANSPORTATION SYSTEMS
(2023)
Article
Biochemistry & Molecular Biology
Harshita Negi, Harshita Saxena, Indrakant K. Singh, Archana Singh
Summary: Lipid-transfer proteins (LTPs) are small proteins that bind to lipids and are found throughout the plant kingdom. They not only play a role in plant defense but also induce allergic reactions in humans. In this study, they examined the allergenicity potential of a family of LTPs (CaLTPs) found in Cicer arietinum. By predicting allergenicity potential and identifying B-cell epitope binding regions, they found that CaLTPs have conserved domains and B-cell epitopes in the same regions as Prup3, a marker allergen for LTPs. Molecular docking and simulations showed that CaLTPs interacted successfully with Immunoglobin E(IgE) and formed stable structures. This study aim to contribute to our understanding of the sensitization and allergenicity potential of CaLTPs.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Biochemistry & Molecular Biology
Rashid Waseem, Anas Shamsi, Tanzeel Khan, Ayesha Anwer, Mohammad Shahid, Syed Naqui Kazim, Md. Imtaiyaz Hassan, Asimul Islam
Summary: This study monitored the formation of advanced glycation end products (AGEs) and aggregates of irisin, a clinically important protein, induced by methyl-glyoxal (MG). The results suggest that glycation of irisin leads to aggregation, and high levels of MG may contribute to reduced irisin levels in pathological conditions such as obesity, diabetes, and neurological disorders.
JOURNAL OF CELLULAR BIOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Manisha Yadav, Indrakant K. Singh, Archana Singh
Summary: This article provides an overview of Dhurrin's properties, distribution, metabolism, and detoxification pathway, as well as its potential application as a natural pest control agent.
Article
Biochemistry & Molecular Biology
Nidhi Goswami, Archana Singh, Shiv Bharadwaj, Amaresh Kumar Sahoo, Indrakant K. Singh
Summary: Neuroblastoma is a challenging tumor to develop drugs for due to its heterogeneity. ALYREF protein has been identified as a target for neuroblastoma treatment, and this study used structure-based drug discovery to find potential inhibitors. The study suggests further evaluation of these compounds for development of a drug against neuroblastoma.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Chemistry, Physical
Ishfaq Ahmad Ahanger, Zahoor Ahmad Parray, Neha Raina, Sania Bashir, Faizan Ahmad, Md. Imtaiyaz Hassan, Mohammad Shahid, Anurag Sharma, Asimul Islam
Summary: This study investigates the effect of heparin on CTAB-induced aggregation of bovine serum albumin (BSA) using biophysical techniques. The results show that heparin completely inhibits CTAB-induced protein aggregation and reduces the apparent rate constant. CTAB acts as a protein-aggregating agent, but heparin prevents the perturbation of secondary and tertiary structure induced by CTAB and the formation of amyloid-like structures. ITC measurements reveal that CTAB and heparin form a complex that does not bind with protein. The CTAB-heparin complex may play a role in inhibiting protein aggregation and could serve as a basis for developing therapeutic strategies for various neurodegenerative complications.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Biochemistry & Molecular Biology
Megha Kumari, Shrishti Naidu, Babita Kumari, Indrakant K. Singh, Archana Singh
Summary: Mechanical wounding, caused by wind, sand, rain, and insects, leads to crop damage and increased pathogen infection. Plants respond to mechanical wounding by altering gene, protein, and metabolite expression. A microarray analysis of maize revealed 407 differentially expressed genes involved in various biotic and abiotic stress responses.
MOLECULAR BIOLOGY REPORTS
(2023)
Review
Biochemistry & Molecular Biology
Neha Basheer, Tomas Smolek, Imtaiyaz Hassan, Fei Liu, Khalid Iqbal, Norbert Zilka, Petr Novak
Summary: Protein kinases (PKs) are extensively studied drug targets, particularly in the field of oncology and neurodegeneration. Tau protein hyperphosphorylation, a post-translational modification observed in Alzheimer's disease (AD), highlights the involvement of PKs in neurodegeneration. The efficacy of protein kinase inhibitors (PKIs) and protein phosphatase 2 A (PP2A) activators in AD has been investigated in preclinical and clinical studies, but the outcomes have been variable. This review examines the results of these studies and evaluates the potential of targeting tau hyperphosphorylation as a disease modifying therapy.
MOLECULAR PSYCHIATRY
(2023)
Review
Plant Sciences
Mohini Kajla, Amit Roy, Indrakant K. Singh, Archana Singh
Summary: Biotic stresses pose a threat to global food security and crop yield worldwide. Plants respond to these stresses by triggering various adaptive changes, including the synthesis and accumulation of plant secondary metabolites. Transcription factors and miRNAs play crucial roles in regulating the production of these metabolites during stress conditions. This review summarizes the role of stress-inducible TFs in synthesizing and accumulating secondary metabolites and highlights how miRNAs fine-tune the expression of stress-responsive transcription factors during biotic stress.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Engineering, Environmental
Amina Ashraf, Ruba Munir, Gadah Albasher, Madiha Ghamkhar, Amna Muneer, Muhammad Yaseen, Tamsal Murtza, Saima Noreen
Summary: In this study, ZnFe2O4 nanocomposites were successfully synthesized and used for dye removal from aqueous solutions. The results showed that pH, adsorbent dosage, contact time, and initial concentration of dyes had an effect on the adsorption performance. The nanocomposites were found to be reusable to some extent.
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING
(2023)
Article
Biotechnology & Applied Microbiology
Prithvi Singh, Aanchal Rathi, Rashmi Minocha, Anuradha Sinha, Mohammad Mahfuzul Haque, Md Imtaiyaz Hassan, Ravins Dohare
Summary: Breast cancer, the second-most common type of cancer and leading cause of cancer-related deaths worldwide, exhibits marked person-to-person variability in susceptibility, phenotypic expression, and prognosis. In this study, we identified PI15 and KRT5 as prognostic hub genes and potential biomarkers in breast cancer, highlighting the need for personalized medicine.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Anam Ashraf, Mohammad Ahmad, Richard Mariadasse, Monis Ali Khan, Saba Noor, Asimul Islam, Md. Imtaiyaz Hassan
Summary: Staphylococcus aureus is a significant human pathogen that is becoming increasingly resistant to antibiotics. This study focuses on thymidine kinase (TK), an enzyme essential for DNA synthesis and repair, and investigates how different pH levels affect its structure and function. The findings indicate that pH variation disrupts the secondary and tertiary structures of TK, leading to aggregate formation at pH 5.0. The enzyme displays maximum activity within the physiological pH range, suggesting a connection between structural changes and enzymatic activity.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Biochemistry & Molecular Biology
Deeba Shamim Jairajpuri, Taj Mohammad, Afzal Hussain, Samira Amir, Urooj Fatima, Mohamed F. AlAjmi, Dharmendra Kumar Yadav, Md. Imtaiyaz Hassan
Summary: This study explored the potential of phytoconstituents as inhibitors of ALK1 using virtual screening and molecular dynamics simulations. Candidine, a phytoconstituent, showed high affinity and specific interactions with the ALK1 active site, stabilizing its structure.
JOURNAL OF MOLECULAR RECOGNITION
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)