Upregulation of oncogene Activin A receptor type I by Helicobacter pylori infection promotes gastric intestinal metaplasia via regulating CDX2

ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis

(2019) Christine M. Hoeman et al.   Nature Communications

Cross-talk among AFAP1-AS1, ACVR1 and microRNA-384 regulates the stemness of pancreatic cancer cells and tumorigenicity in nude mice

(2019) Xu-Bo Wu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Downregulation of tumor suppressor RACK1 by Helicobacter pylori infection promotes gastric carcinogenesis through the integrin β-1/NF-κB signaling pathway

(2019) Yi Hu et al.   CANCER LETTERS

ACVR1 Function in Health and Disease

(2019) Valer et al.   Cells

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Analysis of key genes and signaling pathways involved in Helicobacter pylori -associated gastric cancer based on The Cancer Genome Atlas database and RNA sequencing data

(2018) Yi Hu et al.   HELICOBACTER

Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway

(2018) Nianshuang Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mucosal microbiome dysbiosis in gastric carcinogenesis

(2017) Olabisi Oluwabukola Coker et al.   GUT

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells

(2017) E Raja et al.   ONCOGENE

High-throughput screening for modulators ofACVR1transcription: discovery of potential therapeutics for fibrodysplasia ossificans progressiva

(2016) Serena Cappato et al.   Disease Models & Mechanisms

Pathobiology of Helicobacter pylori–Induced Gastric Cancer

(2016) Manuel Amieva et al.   GASTROENTEROLOGY

Management ofHelicobacter pyloriinfection—the Maastricht V/Florence Consensus Report

(2016) P Malfertheiner et al.   GUT

Regulatory MiR-148a-ACVR1/BMP circuit defines a cancer stem cell-like aggressive subtype of hepatocellular carcinoma

(2015) Lian Li et al.   HEPATOLOGY

The human transcriptome across tissues and individuals

(2015) M. Mele et al.   SCIENCE

Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway

(2015) Zhen Yang et al.   Oncotarget

Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner

(2014) Jinxiong Wei et al.   GUT

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

(2014) Pawel Buczkowicz et al.   NATURE GENETICS

Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin

(2014) O E Olsen et al.   Blood Cancer Journal

Helicobacter pylori and the BMP pathway regulate CDX2 and SOX2 expression in gastric cells

(2012) V. Camilo et al.   CARCINOGENESIS

Reduced expression of PTEN and increased PTEN phosphorylation at residue Ser380 in gastric cancer tissues: A novel mechanism of PTEN inactivation

(2012) Zhen Yang et al.   Clinics and Research in Hepatology and Gastroenterology

The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens

(2011) L. A. Wiley et al.   Disease Models & Mechanisms

Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration

(2009) Diana Romero et al.   CARCINOGENESIS

Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines

(2008) R Barros et al.   JOURNAL OF PATHOLOGY