Concurrent axon and myelin destruction differentiates X‐linked adrenoleukodystrophy from multiple sclerosis

Clinical and radiographic course of arrested cerebral adrenoleukodystrophy

(2020) Eric J. Mallack et al.   NEUROLOGY

MRI brain lesions in asymptomatic boys with X-linked adrenoleukodystrophy

(2019) Afonso P. Liberato et al.   NEUROLOGY

Microglia damage precedes major myelin breakdown in X-linked adrenoleukodystrophy and metachromatic leukodystrophy

(2019) Caroline G. Bergner et al.   GLIA

Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia

(2019) Nynke Oosterhof et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Myelin in the Central Nervous System: Structure, Function, and Pathology

(2019) Christine Stadelmann et al.   PHYSIOLOGICAL REVIEWS

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

(2019) Rocío Rojo et al.   Nature Communications

Microglia Biology: One Century of Evolving Concepts

(2019) Marco Prinz et al.   CELL

Allogeneic HSCT for adult-onset leukoencephalopathy with spheroids and pigmented glia

(2019) Jeffrey M Gelfand et al.   BRAIN

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

(2019) Csaba Cserép et al.   SCIENCE

Impaired plasticity of macrophages in X-linked adrenoleukodystrophy

(2018) Isabelle Weinhofer et al.   BRAIN

Epigenomic signature of adrenoleukodystrophy predicts compromised oligodendrocyte differentiation

(2018) Agatha Schlüter et al.   BRAIN PATHOLOGY

Cortical neuronal densities and cerebral white matter demyelination in multiple sclerosis: a retrospective study

(2018) Bruce D Trapp et al.   LANCET NEUROLOGY

Survival and Functional Outcomes in Boys with Cerebral Adrenoleukodystrophy with and without Hematopoietic Stem Cell Transplantation

(2018) Gerald V. Raymond et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

CSF1R-related leukoencephalopathy

(2018) Takuya Konno et al.   NEUROLOGY

Heat shock protein expression in cerebral X-linked adrenoleukodystrophy reveals astrocyte stress prior to myelin loss

(2017) A. L. Görtz et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy

(2017) Florian Eichler et al.   NEW ENGLAND JOURNAL OF MEDICINE

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions

(2017) Maryam K. Fard et al.   Science Translational Medicine

An updated histological classification system for multiple sclerosis lesions

(2016) Tanja Kuhlmann et al.   ACTA NEUROPATHOLOGICA

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

(2015) Josa M. Frischer et al.   ANNALS OF NEUROLOGY

Brain endothelial dysfunction in cerebral adrenoleukodystrophy

(2015) Patricia L. Musolino et al.   BRAIN

Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy: A paradigm for axonal degeneration

(2015) Stéphane Fourcade et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

X-Linked Adrenoleukodystrophy: Pathogenesis and Treatment

(2014) Marc Engelen et al.   Current Neurology and Neuroscience Reports

Frequent occurrence of cerebral demyelination in adrenomyeloneuropathy

(2014) M. de Beer et al.   NEUROLOGY

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Pathophysiology of X-linked adrenoleukodystrophy

(2013) J. Berger et al.   BIOCHIMIE

X-linked adrenoleukodystrophy: very long-chain fatty acid metabolism is severely impaired in monocytes but not in lymphocytes

(2013) F. D. Weber et al.   HUMAN MOLECULAR GENETICS

Regulation of Axon Degeneration after Injury and in Development by the Endogenous Calpain Inhibitor Calpastatin

(2013) Jing Yang et al.   NEURON

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Failure of Repeated Cyclophosphamide Pulse Therapy in Childhood Cerebral X-Linked Adrenoleukodystrophy

(2012) Gabriella Horvath et al.   NEUROPEDIATRICS

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

General Aspects and Neuropathology of X-Linked Adrenoleukodystrophy

(2010) Isidro Ferrer et al.   BRAIN PATHOLOGY

In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis

(2010) Volker Siffrin et al.   IMMUNITY

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Is microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy?

(2008) Florian S. Eichler et al.   ANNALS OF NEUROLOGY