The H3K9 histone methyltransferase G9a modulates renal ischemia reperfusion injury by targeting Sirt1

N-Cadherin Overexpression Mobilizes the Protective Effects of Mesenchymal Stromal Cells Against Ischemic Heart Injury Through a β-Catenin–Dependent Manner

(2020) Wenjun Yan et al.   CIRCULATION RESEARCH

H2S- and NO-releasing gasotransmitter platform: A crosstalk signaling pathway in the treatment of acute kidney injury

(2020) Joana Claudio Pieretti et al.   PHARMACOLOGICAL RESEARCH

ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule

(2020) Di Liu et al.   Science Advances

Isoliquiritigenin prevents hyperglycemia-induced renal injuries by inhibiting inflammation and oxidative stress via SIRT1-dependent mechanism

(2020) Xiaozhong Huang et al.   Cell Death & Disease

Long noncoding RNA MALAT1 mediates high glucose-induced glomerular endothelial cell injury by epigenetically inhibiting klotho via methyltransferase G9a

(2019) Yebei Li et al.   IUBMB LIFE

Inhibition of Brd4 alleviates renal ischemia/reperfusion injury-induced apoptosis and endoplasmic reticulum stress by blocking FoxO4-mediated oxidative stress

(2019) Hao Liu et al.   Redox Biology

Histone methyltransferase G9a protects against acute liver injury through GSTP1

(2019) Yu Zhang et al.   CELL DEATH AND DIFFERENTIATION

Enhancer of zeste homolog 2 modulates oxidative stress‐mediated pyroptosis in vitro and in a mouse kidney ischemia‐reperfusion injury model

(2019) Hao Liu et al.   FASEB JOURNAL

Acute kidney injury

(2019) Claudio Ronco et al.   LANCET

PSTPIP2 connects DNA methylation to macrophage polarization in CCL4-induced mouse model of hepatic fibrosis

(2018) Yang Yang et al.   ONCOGENE

Global epidemiology and outcomes of acute kidney injury

(2018) Eric A. J. Hoste et al.   Nature Reviews Nephrology

Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression

(2016) Taisuke Irifuku et al.   KIDNEY INTERNATIONAL

Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation

(2016) Lisha Zhao et al.   MOLECULES

Ischemic Preconditioning Confers Epigenetic Repression of Mtor and Induction of Autophagy Through G9a‐Dependent H3K9 Dimethylation

(2016) Olof Gidlöf et al.   Journal of the American Heart Association

Inhibition of Histone Methyltransferases SUV39H1 and G9a Leads to Neuroprotection in an in vitro Model of Cerebral Ischemia

(2015) Sophie Schweizer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Heterogeneity of epigenetic changes at ischemia/reperfusion- and endotoxin-induced acute kidney injury genes

(2015) Daniel Mar et al.   KIDNEY INTERNATIONAL

Sirtuin 1 Activation Stimulates Mitochondrial Biogenesis and Attenuates Renal Injury After Ischemia-Reperfusion

(2014) Adam Khader et al.   TRANSPLANTATION

A General Molecular Affinity Strategy for Global Detection and Proteomic Analysis of Lysine Methylation

(2013) Kaitlyn E. Moore et al.   MOLECULAR CELL

Renal Protective Effects of Resveratrol

(2013) Munehiro Kitada et al.   Oxidative Medicine and Cellular Longevity

Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death

(2013) H Yu et al.   Cell Death & Disease

Discovering common combinatorial histone modification patterns in the human genome

(2012) Changgui Linghu et al.   GENE

Temporal Changes in Incidence of Dialysis-Requiring AKI

(2012) R. K. Hsu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Histone Methyltransferase Inhibitor BIX01294 Enhances the Cardiac Potential of Bone Marrow Cells

(2012) Nadejda V. Mezentseva et al.   STEM CELLS AND DEVELOPMENT

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics

(2008) Leon G. Fine et al.   KIDNEY INTERNATIONAL