Tumor necrosis factor-alpha and interferon-gamma induce inflammasome-mediated corneal endothelial cell death

Impairment of the autophagy-lysosomal pathway and activation of pyroptosis in macular corneal dystrophy

(2020) Tao Zheng et al.   Cell Death Discovery

Airborne particulate matter (PM2.5) triggers cornea inflammation and pyroptosis via NLRP3 activation

(2020) Liangliang Niu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Inflammasome Proteins as Inflammatory Biomarkers of Age-Related Macular Degeneration

(2020) Cailey Weaver et al.   Translational Vision Science & Technology

Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation

(2019) Hiroaki Shimizu et al.   Scientific Reports

Pyroptosis in pterygium pathogenesis

(2018) Naiyu Sun et al.   BIOSCIENCE REPORTS

Mechanisms of Gasdermin Family Members in Inflammasome Signaling and Cell Death

(2018) Shouya Feng et al.   JOURNAL OF MOLECULAR BIOLOGY

Evidence for the activation of pyroptotic and apoptotic pathways in RPE cells associated with NLRP3 inflammasome in the rodent eye

(2018) Jiangyuan Gao et al.   Journal of Neuroinflammation

Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy

(2018) Niina Piippo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Negative impact of dextran in organ culture media for pre-stripped tissue preservation on DMEK (Descemet membrane endothelial keratoplasty) outcome

(2018) Alaadin Abdin et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy

(2018) Deepika Sharma et al.   JOURNAL OF CLINICAL INVESTIGATION

Contribution of the inflammasome to inflammaging

(2018) Nancy H. Mejias et al.   Journal of Inflammation-London

Cytokine Levels in the Aqueous Humor Are Associated With Corneal Thickness in Eyes With Bullous Keratopathy

(2018) Natsume Suzuki et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn

(2017) Fang Bian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Gasdermins: Effectors of Pyroptosis

(2017) Stephen B. Kovacs et al.   TRENDS IN CELL BIOLOGY

Semi-quantitative assessments of dextran toxicity on corneal endothelium: conceptual design of a predictive algorithm

(2016) Filip Filev et al.   CELL AND TISSUE BANKING

Acidification changes affect the inflammasome in human nucleus pulposus cells

(2016) Frank J. Brand et al.   Journal of Inflammation-London

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Therapeutics targeting the inflammasome after central nervous system injury

(2016) Juan Pablo de Rivero Vaccari et al.   Translational Research

Oxidative stress and premature senescence in corneal endothelium following penetrating keratoplasty in an animal model

(2016) Xiaowen Zhao et al.   BMC Ophthalmology

Gasdermin D: the long-awaited executioner of pyroptosis

(2015) Si Ming Man et al.   CELL RESEARCH

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration

(2015) Jiangyuan Gao et al.   MEDIATORS OF INFLAMMATION

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye

(2014) Qinxiang Zheng et al.   EXPERIMENTAL EYE RESEARCH

Inflammatory caspases are innate immune receptors for intracellular LPS

(2014) Jianjin Shi et al.   NATURE

Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1  production in acute glaucoma

(2014) W. Chi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of mitochondria ROS generation in ethanol-induced NLRP3 inflammasome activation and cell death in astroglial cells

(2014) Silvia Alfonso-Loeches et al.   Frontiers in Cellular Neuroscience

Reactive oxygen species at the crossroads of inflammasome and inflammation

(2014) Anantha Harijith et al.   Frontiers in Physiology

DNA-responsive inflammasomes and their regulators in autoimmunity

(2011) Divaker Choubey   CLINICAL IMMUNOLOGY

The unfolded protein response in human corneal endothelial cells following hypothermic storage: Implications of a novel stress pathway

(2011) William L. Corwin et al.   CRYOBIOLOGY

Understanding the mechanism of IL-1β secretion

(2011) Gloria Lopez-Castejon et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Proliferative capacity of corneal endothelial cells

(2011) Nancy C. Joyce   EXPERIMENTAL EYE RESEARCH

Human Corneal Endothelial Cell Expansion for Corneal Endothelium Transplantation: An Overview

(2011) Gary S. L. Peh et al.   TRANSPLANTATION

Evidence of Oxidative Stress in the Pathogenesis of Fuchs Endothelial Corneal Dystrophy

(2010) Ula V. Jurkunas et al.   AMERICAN JOURNAL OF PATHOLOGY

Interferon-Inducible p200-Family Proteins as Novel Sensors of Cytoplasmic DNA: Role in Inflammation and Autoimmunity

(2010) Divaker Choubey et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Dynamic Regulation of Barrier Integrity of the Corneal Endothelium

(2010) Sangly P. Srinivas   OPTOMETRY AND VISION SCIENCE

Changing Paradigms in Biopreservation

(2009) John M. Baust et al.   BIOPRESERVATION AND BIOBANKING