An evidence update on the protective mechanism of tangeretin against neuroinflammation based on network pharmacology prediction and transcriptomic analysis

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity

(2019) Peter van Galen et al.   CELL

Lipid mediators in immune regulation and resolution

(2019) Derek W. Gilroy et al.   BRITISH JOURNAL OF PHARMACOLOGY

Yinchenhao decoction suppresses rat liver fibrosis involved in an apoptosis regulation mechanism based on network pharmacology and transcriptomic analysis

(2019) Fei-Fei Cai et al.   BIOMEDICINE & PHARMACOTHERAPY

IMPRes-Pro: A high dimensional multiomics integration method for in silico hypothesis generation

(2019) Yuexu Jiang et al.   METHODS

Physiological and transcriptomic analyses reveal the molecular networks of responses induced by exogenous trehalose in plant

(2019) Yongchun Shi et al.   PLoS One

Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA Stabilization

(2019) Alina Astakhova et al.   Cells

Ferulic acid attenuates oxidative DNA damage and inflammatory responses in microglia induced by benzo(a)pyrene

(2019) Yongfen Bao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease

(2018) Paul W. Hook et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Attenuation of tert-Butyl Hydroperoxide (t-BHP)-Induced Oxidative Damage in HepG2 Cells by Tangeretin: Relevance of the Nrf2–ARE and MAPK Signaling Pathways

(2018) Fuqiang Liang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lignans from Schisandra chinensis rattan stems suppresses primary Aβ1-42-induced microglia activation via NF-κB/MAPK signaling pathway

(2018) Bingyou Yang et al.   NATURAL PRODUCT RESEARCH

Carnosic acid, Tangeretin, and Ginkgolide-B Anti-Neoplastic Cytotoxicity in Dual Combination with Dexamethasone-[anti-EGFR] in Pulmonary Adenocarcinoma (A549)

(2018) C. P. Coyne et al.   Anti-Cancer Agents in Medicinal Chemistry

TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia

(2018) Ji-Won Lee et al.   Autophagy

Therapeutic targets of vitamin C on liver injury and associated biological mechanisms: A study of network pharmacology

(2018) Min Su et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Simultaneous Separation and Purification of Five Polymethoxylated Flavones from “Dahongpao” Tangerine (Citrus tangerina Tanaka) Using Macroporous Adsorptive Resins Combined with Prep-HPLC

(2018) Zhenqing Li et al.   MOLECULES

Andrographolide attenuates microglia-mediated Aβ neurotoxicity partially through inhibiting NF-κB and JNK MAPK signaling pathway

(2017) Rui Yang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging

(2017) Ainhoa Plaza-Zabala et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In Vivo Imaging of Microglial Calcium Signaling in Brain Inflammation and Injury

(2017) Petr Tvrdik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Src-family kinases activation in spinal microglia contributes to central sensitization and chronic pain after lumbar disc herniation

(2017) Yangliang Huang et al.   Molecular Pain

Therapeutic implications of toll-like receptors in peripheral neuropathic pain

(2017) Krishan K. Thakur et al.   PHARMACOLOGICAL RESEARCH

Tangeretin sensitises human lung cancer cells to TRAILinduced apoptosis via ROS-JNK/ERK-CHOP pathwaymediated up-regulation of death receptor 5

(2017) Xi Liu et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Amyloid-β25–35, an Amyloid-β1–42 Surrogate, and Proinflammatory Cytokines Stimulate VEGF-A Secretion by Cultured, Early Passage, Normoxic Adult Human Cerebral Astrocytes

(2017) Anna Chiarini et al.   JOURNAL OF ALZHEIMERS DISEASE

Identification of the chemical compositions of Ponkan peel by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

(2016) Ying Yang et al.   Analytical Methods

Systems pharmacology – Towards the modeling of network interactions

(2016) Meindert Danhof   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

PI3k/Akt signalling pathway plays a crucial role in the anti-inflammatory effects of curcumin in LPS-activated microglia

(2016) Antonia Cianciulli et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Biginkgosides A–I, Unexpected Minor Dimeric Flavonol Diglycosidic Truxinate and Truxillate Esters from Ginkgo biloba Leaves and Their Antineuroinflammatory and Neuroprotective Activities

(2016) Guang-Lei Ma et al.   JOURNAL OF NATURAL PRODUCTS

Anti-Inflammatory and Antioxidant Mechanism of Tangeretin in Activated Microglia

(2016) Yu Young Lee et al.   Journal of Neuroimmune Pharmacology

Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro

(2016) Lalita Subedi et al.   PHYTOMEDICINE

An integrated global chemomics and system biology approach to analyze the mechanisms of the traditional Chinese medicinal preparation Eriobotrya japonica – Fritillaria usuriensis dropping pills for pulmonary diseases

(2015) Jin Tao et al.   BMC Complementary and Alternative Medicine

PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy

(2015) S. P. Patel et al.   MOLECULAR CANCER THERAPEUTICS

Insulin-like growth factor-1 induces regulatory T cell-mediated suppression of allergic contact dermatitis in mice

(2014) B. Johannesson et al.   Disease Models & Mechanisms

Tangeretin exerts anti-neuroinflammatory effects via NF-κB modulation in lipopolysaccharide-stimulated microglial cells

(2014) Zunpeng Shu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

mTOR Signaling Inhibition Modulates Macrophage/Microglia-Mediated Neuroinflammation and Secondary Injury via Regulatory T Cells after Focal Ischemia

(2014) L. Xie et al.   JOURNAL OF IMMUNOLOGY

Transcriptome Analysis of Psoriasis in a Large Case–Control Sample: RNA-Seq Provides Insights into Disease Mechanisms

(2014) Bingshan Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Stroke Neuroprotection: Oestrogen and Insulin-Like Growth Factor-1 Interactions and the Role of Microglia

(2013) F. Sohrabji et al.   JOURNAL OF NEUROENDOCRINOLOGY

A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis

(2012) M.-A. Dillies et al.   BRIEFINGS IN BIOINFORMATICS

Relationship Between the Neuroprotective Effects of Insulin-Like Growth Factor-1 and 17β-Oestradiol in Human Neuroblasts

(2012) P. Luciani et al.   JOURNAL OF NEUROENDOCRINOLOGY

Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury

(2012) Wen-sheng Qu et al.   Journal of Neuroinflammation

Microarrays, deep sequencing and the true measure of the transcriptome

(2011) John H Malone et al.   BMC BIOLOGY

Attenuation of pro-inflammatory mediators in LPS-stimulated BV2 microglia by chitooligosaccharides via the MAPK signaling pathway

(2011) Ratih Pangestuti et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

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(2011) David C. Swinney et al.   NATURE REVIEWS DRUG DISCOVERY

Src-family and Syk Kinases in Activating and Inhibitory Pathways in Innate Immune Cells: Signaling Cross Talk

(2010) C. A. Lowell   Cold Spring Harbor Perspectives in Biology

Tyrosine Kinases and Inflammatory Signalling

(2009) Theresa Page et al.   CURRENT MOLECULAR MEDICINE

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain

(2008) J.E. Simpson et al.   NEUROBIOLOGY OF AGING