Assessing the Toxicity of 17α-Ethinylestradiol in Rainbow Trout Using a 4-Day Transcriptomics Benchmark Dose (BMD) Embryo Assay

Development of a Comprehensive Toxicity Pathway Model for 17α-Ethinylestradiol in Early Life Stage Fathead Minnows (Pimephales promelas)

(2021) Alper James G. Alcaraz et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

FastBMD: an online tool for rapid benchmark dose-response analysis of transcriptomics data

(2020) Jessica Ewald et al.   BIOINFORMATICS

Repeatability and reproducibility of the RTgill-W1 cell line assay for predicting fish acute toxicity

(2019) Melanie Fischer et al.   TOXICOLOGICAL SCIENCES

EcoToxChip: A next-generation toxicogenomics tool for chemical prioritization and environmental management

(2019) Niladri Basu et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)

(2019) Uku Raudvere et al.   NUCLEIC ACIDS RESEARCH

Transcriptomic analysis of the impacts of ethinylestradiol (EE2) and its consequences for proliferative kidney disease outcome in rainbow trout (Oncorhynchus mykiss)

(2019) Christyn Bailey et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Transcriptomic points-of-departure from short-term exposure studies are protective of chronic effects for fish exposed to estrogenic chemicals

(2019) Florence Pagé-Larivière et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A critical review of histopathological findings associated with endocrine and non-endocrine hepatic toxicity in fish models

(2018) Jeffrey C. Wolf et al.   AQUATIC TOXICOLOGY

A Reduced Transcriptome Approach to Assess Environmental Toxicants Using Zebrafish Embryo Test

(2018) Pingping Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Applicability of the fish embryo acute toxicity (FET) test (OECD 236) in the regulatory context of Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH)

(2018) Marta Sobanska et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Systems Analysis of the Liver Transcriptome in Adult Male Zebrafish Exposed to the Plasticizer (2-Ethylhexyl) Phthalate (DEHP)

(2018) Matthew Huff et al.   Scientific Reports

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Synthetic chemicals as agents of global change

(2017) Emily S Bernhardt et al.   FRONTIERS IN ECOLOGY AND THE ENVIRONMENT

Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment

(2016) Reza Farmahin et al.   ARCHIVES OF TOXICOLOGY

On the Dependency of Cellular Protein Levels on mRNA Abundance

(2016) Yansheng Liu et al.   CELL

Concentrations of levonorgestrel and ethinylestradiol in wastewater effluents: Is the progestin also cause for concern?

(2016) Olivia C. King et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Alternative approaches to vertebrate ecotoxicity tests in the 21st century: A review of developments over the last 2 decades and current status

(2016) Adam Lillicrap et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

From single chemicals to mixtures—Reproductive effects of levonorgestrel and ethinylestradiol on the fathead minnow

(2015) Tamsin J. Runnalls et al.   AQUATIC TOXICOLOGY

17α-Ethinylestradiol (EE2) effect on global gene expression in primary rainbow trout (Oncorhynchus mykiss) hepatocytes

(2015) Maria T. Hultman et al.   AQUATIC TOXICOLOGY

InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

(2015) Henry Heberle et al.   BMC BIOINFORMATICS

Comparison of the sensitivity of four native Canadian fish species to 17-α ethinylestradiol, using an in vitro liver explant assay

(2015) Shawn C. Beitel et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Transgenerational effects from early developmental exposures to bisphenol A or 17α-ethinylestradiol in medaka, Oryzias latipes

(2015) Ramji K. Bhandari et al.   Scientific Reports

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Occurrence of 17α-ethynylestradiol (EE2) in the environment and effect on exposed biota: a review

(2014) Ahmad Zaharin Aris et al.   ENVIRONMENT INTERNATIONAL

Understanding Receptor-Mediated Effects in Rainbow Trout: In Vitro–in Vivo Extrapolation Using Physiologically Based Toxicokinetic Models

(2014) Markus Brinkmann et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Multi-enzyme digestion FASP and the ‘Total Protein Approach’-based absolute quantification of the Escherichia coli proteome

(2014) Jacek R. Wiśniewski et al.   Journal of Proteomics

Intersex Occurrence in Rainbow Trout (Oncorhynchus mykiss) Male Fry Chronically Exposed to Ethynylestradiol

(2014) Sophie Depiereux et al.   PLoS One

The effects of 17-α-ethinylestradiol (EE2) on molecular signaling cascades in mummichog (Fundulus heteroclitus)

(2013) M.A. Doyle et al.   AQUATIC TOXICOLOGY

Identification of Estrogen Target Genes during Zebrafish Embryonic Development through Transcriptomic Analysis

(2013) Ruixin Hao et al.   PLoS One

Temporal Concordance Between Apical and Transcriptional Points of Departure for Chemical Risk Assessment

(2013) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

Effects of 17α-ethynylestradiol on sexual differentiation and development of the African clawed frog (Xenopus laevis)

(2012) Amber R. Tompsett et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Predicted-no-effect concentrations for the steroid estrogens estrone, 17β-estradiol, estriol, and 17α-ethinylestradiol

(2012) Daniel J. Caldwell et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

An integrated transcriptomic and proteomic approach characterizing estrogenic and metabolic effects of 17 α-ethinylestradiol in zebrafish (Danio rerio)

(2010) Marijke De Wit et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Identification of estrogen-responsive vitelline envelope protein fragments from rainbow trout (Oncorhynchus mykiss) plasma using mass spectrometry

(2010) K. Salinas et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Regulatory aspects on the use of fish embryos in environmental toxicology

(2010) Marlies Halder et al.   Integrated Environmental Assessment and Management

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Derivation of an Aquatic Predicted No-Effect Concentration for the Synthetic Hormone, 17α-Ethinyl Estradiol

(2008) Daniel J. Caldwell et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Environmentally Relevant Concentrations of 17α-Ethinylestradiol (EE2) Interfere With the Growth Hormone (GH)/Insulin-Like Growth Factor (IGF)-I System in Developing Bony Fish

(2008) Natallia Shved et al.   TOXICOLOGICAL SCIENCES