Functional genomics to assess biological responses to marine pollution at physiological and evolutionary timescales: toward a vision of predictive ecotoxicology

Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus)

(2015) Neelakanteswar Aluru et al.   AQUATIC TOXICOLOGY

Evolved resistance to PCB- and PAH-induced cardiac teratogenesis, and reduced CYP1A activity in Gulf killifish (Fundulus grandis) populations from the Houston Ship Channel, Texas

(2014) Elias M. Oziolor et al.   AQUATIC TOXICOLOGY

The toxicological application of transcriptomics and epigenomics in zebrafish and other teleosts

(2014) T. D. Williams et al.   Briefings in Functional Genomics

Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone

(2014) A. Feswick et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Natural Selection Canalizes Expression Variation of Environmentally Induced Plasticity-Enabling Genes

(2014) Joseph R. Shaw et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genomic and Genotoxic Responses to Controlled Weathered-Oil Exposures Confirm and Extend Field Studies on Impacts of the Deepwater Horizon Oil Spill on Native Killifish

(2014) Whitney Pilcher et al.   PLoS One

The effects of 17-α-ethinylestradiol (EE2) on molecular signaling cascades in mummichog (Fundulus heteroclitus)

(2013) M.A. Doyle et al.   AQUATIC TOXICOLOGY

Genomic and physiological responses to strong selective pressure during late organogenesis: few gene expression changes found despite striking morphological differences

(2013) Goran Bozinovic et al.   BMC GENOMICS

Multitissue Molecular, Genomic, and Developmental Effects of the Deepwater Horizon Oil Spill on Resident Gulf Killifish (Fundulus grandis)

(2013) Benjamin Dubansky et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Evolutionary Patterns in Trace Metal (Cd and Zn) Efflux Capacity in Aquatic Organisms

(2013) Monica D. Poteat et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Mutation Load: The Fitness of Individuals in Populations Where Deleterious Alleles Are Abundant

(2012) Aneil F. Agrawal et al.   Annual Review of Ecology Evolution and Systematics

Systems Pharmacology to Predict Drug Toxicity: Integration Across Levels of Biological Organization

(2012) Jane P.F. Bai et al.   Annual Review of Pharmacology and Toxicology

RNA-Seq reveals complex genetic response to deepwater horizon oil release in Fundulus grandis

(2012) Tzintzuni I Garcia et al.   BMC GENOMICS

Phylogeny meets ecotoxicology: evolutionary patterns of sensitivity to a common insecticide

(2012) John I. Hammond et al.   Evolutionary Applications

CYP1A expression fails to demonstrate exposure-response relationship

(2012) K. D. Jenkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reply to Jenkins et al.: Evidence for contaminating oil exposure is closely linked in space and time to biological effects

(2012) A. Whitehead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic research in aquatic toxicology: Perspectives and future directions

(2011) Mark E. Hahn   AQUATIC TOXICOLOGY

Transcriptomic assessment of resistance to effects of an aryl hydrocarbon receptor (AHR) agonist in embryos of Atlantic killifish (Fundulus heteroclitus) from a marine Superfund site

(2011) Marjorie F Oleksiak et al.   BMC GENOMICS

Phylogenetic signals and ecotoxicological responses: potential implications for aquatic biomonitoring

(2011) Melissa E. Carew et al.   ECOTOXICOLOGY

Conserved toxic responses across divergent phylogenetic lineages: a meta-analysis of the neurotoxic effects of RDX among multiple species using toxicogenomics

(2011) Natàlia Garcia-Reyero et al.   ECOTOXICOLOGY

Novel Computational Identification of Highly Selective Biomarkers of Pollutant Exposure

(2011) David Weisman et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Genomic and physiological footprint of the Deepwater Horizon oil spill on resident marsh fishes

(2011) A. Whitehead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common mechanism underlies repeated evolution of extreme pollution tolerance

(2011) A. Whitehead et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mechanistic Basis of Resistance to PCBs in Atlantic Tomcod from the Hudson River

(2011) I. Wirgin et al.   SCIENCE

Arsenic Exposure to Killifish During Embryogenesis Alters Muscle Development

(2011) Kristen M. Gaworecki et al.   TOXICOLOGICAL SCIENCES

Embryonic gene expression among pollutant resistant and sensitive Fundulus heteroclitus populations

(2010) Goran Bozinovic et al.   AQUATIC TOXICOLOGY

AHR2 mediates cardiac teratogenesis of polycyclic aromatic hydrocarbons and PCB-126 in Atlantic killifish (Fundulus heteroclitus)

(2010) Bryan W. Clark et al.   AQUATIC TOXICOLOGY

Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation

(2010) Choong Ung et al.   BMC GENOMICS

Effects of Diazepam on Gene Expression and Link to Physiological Effects in Different Life Stages in ZebrafishDanio rerio

(2010) Daniela M. Oggier et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Reverse engineering adverse outcome pathways

(2010) Edward J. Perkins et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adaptation of the Estuarine Fish Fundulus heteroclitus (Atlantic Killifish) to Polychlorinated Biphenyls (PCBs)

(2010) Diane E. Nacci et al.   Estuaries and Coasts

Dose-responsive gene expression changes in juvenile and adult mummichogs (Fundulus heteroclitus) after arsenic exposure

(2010) Horacio O. Gonzalez et al.   MARINE ENVIRONMENTAL RESEARCH

Comparative transcriptomics implicates mechanisms of evolved pollution tolerance in a killifish population

(2010) A. WHITEHEAD et al.   MOLECULAR ECOLOGY

The Growing Human Footprint on Coastal and Open-Ocean Biogeochemistry

(2010) S. C. Doney   SCIENCE

An Information-Rich Alternative, Chemicals Testing Strategy Using a High Definition Toxicogenomics and Zebrafish (Danio rerio) Embryos

(2010) Ashley D. Sawle et al.   TOXICOLOGICAL SCIENCES

Dithiocarbamates Induce Craniofacial Abnormalities and Downregulate sox9a during Zebrafish Development

(2010) Antonius Leonardus van Boxtel et al.   TOXICOLOGICAL SCIENCES

Incorporating Zebrafish Omics into Chemical Biology and Toxicology

(2010) Hendrian Sukardi et al.   Zebrafish

Adaptation, Plasticity, and Extinction in a Changing Environment: Towards a Predictive Theory

(2010) Luis-Miguel Chevin et al.   PLOS BIOLOGY

Framework for traits-based assessment in ecotoxicology

(2010) Mascha N Rubach et al.   Integrated Environmental Assessment and Management

Changes in gene expression due to chronic exposure to environmental pollutants

(2008) Marjorie F. Oleksiak   AQUATIC TOXICOLOGY

Microarray Analysis Reveals a Mechanism of Phenolic Polybrominated Diphenylether Toxicity in Zebrafish

(2008) Antonius L. van Boxtel et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Evolution of metal hyperaccumulation required cis-regulatory changes and triplication of HMA4

(2008) Marc Hanikenne et al.   NATURE

Aquatic insect ecophysiological traits reveal phylogenetically based differences in dissolved cadmium susceptibility

(2008) D. B. Buchwalter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zebrafish Whole-Adult-Organism Chemogenomics for Large-Scale Predictive and Discovery Chemical Biology

(2008) Siew Hong Lam et al.   PLoS Genetics