期刊
FEBS LETTERS
卷 590, 期 4, 页码 550-558出版社
WILEY-BLACKWELL
DOI: 10.1002/1873-3468.12070
关键词
arabinanolytic regulator; pentose catabolic pathway; rice-blast fungus
资金
- Netherlands Organisation for Scientific Research (NWO)
- Netherlands Genomics Initiative [93511035]
- BE-Basic foundation [F10.001.01]
In this study we identified the L-arabinose-responsive regulator of Pyricularia oryzae that regulates L-arabinose release and catabolism. Previously we identified the Zn2Cys6 transcription factor (TF), AraR, that has this role in the Trichocomaceae family (Eurotiales), but is absent in other fungi. Candidate Zn2Cys6 TF genes were selected according to their transcript profiles on L-arabinose. Deletion mutants of these genes were screened for their growth phenotype on L-arabinose. One mutant, named Delta ara1, was further analyzed. Our analysis demonstrated that Ara1 from P. oryzae is the functional analog of AraR from A. niger, while there is no significant sequence similarity between them.
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