Galectin-3 regulates inflammasome activation in cholestatic liver injury

Galectin-3 suppresses mucosal inflammation and reduces disease severity in experimental colitis

(2015) Hwei-Fang Tsai et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Innate immunity drives xenobiotic-induced murine autoimmune cholangitis

(2014) C.-H. Chang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

M1- and M2-macrophage polarization in rat liver cirrhosis induced by thioacetamide (TAA), focusing on Iba1 and galectin-3

(2014) Kavindra Kumara Wijesundera et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Regulation of Alternative Macrophage Activation by Galectin-3

(2014) A. C. MacKinnon et al.   JOURNAL OF IMMUNOLOGY

NLRP3 inflammasome activation is required for fibrosis development in NAFLD

(2014) Alexander Wree et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

c-Jun N-Terminal Kinase 1/c-Jun Activation of the p53/MicroRNA 34a/Sirtuin 1 Pathway Contributes to Apoptosis Induced by Deoxycholic Acid in Rat Liver

(2014) D. M. S. Ferreira et al.   MOLECULAR AND CELLULAR BIOLOGY

Animal Models of Primary Biliary Cirrhosis

(2014) Jinjun Wang et al.   SEMINARS IN LIVER DISEASE

Clonality, activated antigen-specific CD8+T cells, and development of autoimmune cholangitis in dnTGFβRII mice

(2013) Kazuhito Kawata et al.   HEPATOLOGY

IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: Implications for therapy

(2013) Chen-Yen Yang et al.   HEPATOLOGY

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Deficiency in Galectin-3 Promotes Hepatic Injury in CDAA Diet-Induced Nonalcoholic Fatty Liver Disease

(2012) Kazuhiro Nomoto et al.   TheScientificWorldJOURNAL

Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo

(2011) Joy X. Jiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis

(2011) Markus Bosmann et al.   FASEB JOURNAL

Caspase-1-Processed Cytokines IL-1  and IL-18 Promote IL-17 Production by    and CD4 T Cells That Mediate Autoimmunity

(2011) S. J. Lalor et al.   JOURNAL OF IMMUNOLOGY

Inflammasome-IL-1-Th17 response in allergic lung inflammation

(2011) A.-G. Besnard et al.   Journal of Molecular Cell Biology

Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor β receptor II improves colitis but exacerbates autoimmune cholangitis

(2010) Weici Zhang et al.   HEPATOLOGY

Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis

(2010) Ana Lleo et al.   HEPATOLOGY

Gene Silencing of NALP3 Protects Against Liver Ischemia–Reperfusion Injury in Mice

(2010) Ping Zhu et al.   HUMAN GENE THERAPY

Galectin-3 ablation protects mice from diet-induced NASH: A major scavenging role for galectin-3 in liver

(2010) Carla Iacobini et al.   JOURNAL OF HEPATOLOGY

Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells

(2009) Eileen Looby et al.   BMC CANCER

Galectin-3 regulates T-cell functions

(2009) Daniel K. Hsu et al.   IMMUNOLOGICAL REVIEWS

Galectins in innate immunity: dual functions of host soluble β-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs)

(2009) Sachiko Sato et al.   IMMUNOLOGICAL REVIEWS

Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse

(2009) H.-Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatic IL-17 responses in human and murine primary biliary cirrhosis

(2008) Ruth Y.Z. Lan et al.   JOURNAL OF AUTOIMMUNITY