标题
Update on Lynch syndrome genomics
作者
关键词
Lynch syndrome, Mutation, Epimutation, Tumor spectrum, DNA mismatch repair
出版物
Familial Cancer
Volume 15, Issue 3, Pages 385-393
出版商
Springer Nature
发表日期
2016-02-12
DOI
10.1007/s10689-016-9882-8
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers
- (2015) Anne ML Jansen et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Diagnosis of Constitutional Mismatch Repair-Deficiency Syndrome Based on Microsatellite Instability and Lymphocyte Tolerance to Methylating Agents
- (2015) Sahra Bodo et al. GASTROENTEROLOGY
- Germline Mutations in FAN1 Cause Hereditary Colorectal Cancer by Impairing DNA Repair
- (2015) Nuria Seguí et al. GASTROENTEROLOGY
- Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome
- (2015) Matthew B. Yurgelun et al. GASTROENTEROLOGY
- Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer
- (2015) Michael Kloth et al. GUT
- Lynch Syndrome Caused by Germline PMS2 Mutations: Delineating the Cancer Risk
- (2015) Sanne W. ten Broeke et al. JOURNAL OF CLINICAL ONCOLOGY
- Prevalence ofMLH1constitutional epimutations as a cause of Lynch syndrome in unselected versus selected consecutive series of patients with colorectal cancer
- (2015) Adela Castillejo et al. JOURNAL OF MEDICAL GENETICS
- Variation in cancer risk among tissues can be explained by the number of stem cell divisions
- (2015) C. Tomasetti et al. SCIENCE
- DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas
- (2015) Satu Valo et al. Clinical Epigenetics
- Mismatch repair genes founder mutations and cancer susceptibility in Lynch syndrome
- (2014) G. Ponti et al. CLINICAL GENETICS
- Germline Mutation of RPS20, Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency
- (2014) Taina T. Nieminen et al. GASTROENTEROLOGY
- Colon and Endometrial Cancers With Mismatch Repair Deficiency Can Arise From Somatic, Rather Than Germline, Mutations
- (2014) Sigurdis Haraldsdottir et al. GASTROENTEROLOGY
- Somatic aberrations of mismatch repair genes as a cause of microsatellite-unstable cancers
- (2014) Willemina RR Geurts-Giele et al. JOURNAL OF PATHOLOGY
- Familial colorectal cancer type X: genetic profiles and phenotypic features
- (2014) Mev Dominguez-Valentin et al. MODERN PATHOLOGY
- Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X
- (2014) Eduard Schulz et al. Nature Communications
- DNA Mismatch Repair and Oxidative DNA Damage: Implications for Cancer Biology and Treatment
- (2014) Gemma Bridge et al. Cancers
- MutS Homologues hMSH4 and hMSH5: Genetic Variations, Functions, and Implications in Human Diseases
- (2013) Nicole Clark et al. CURRENT GENOMICS
- The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype
- (2013) Chau-To Kwok et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- The InSiGHT database: utilizing 100 years of insights into Lynch Syndrome
- (2013) J. P. Plazzer et al. Familial Cancer
- Somatic Mutations in MLH1 and MSH2 Are a Frequent Cause of Mismatch-Repair Deficiency in Lynch Syndrome-Like Tumors
- (2013) Arjen R. Mensenkamp et al. GASTROENTEROLOGY
- Integrated genomic characterization of endometrial carcinoma
- (2013) Gad Getz et al. NATURE
- Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database
- (2013) Bryony A Thompson et al. NATURE GENETICS
- Postreplicative Mismatch Repair
- (2013) J. Jiricny Cold Spring Harbor Perspectives in Biology
- Identifying Molecular Targets of Lifestyle Modifications in Colon Cancer Prevention
- (2013) Molly M. Derry et al. Frontiers in Oncology
- Dietary patterns and colorectal adenomas in Lynch syndrome
- (2012) Akke Botma et al. CANCER
- Microsatellite Instability and DNA Mismatch Repair Protein Deficiency in Lynch Syndrome Colorectal Polyps
- (2012) M. B. Yurgelun et al. Cancer Prevention Research
- Identification of constitutional MLH1 epimutations and promoter variants in colorectal cancer patients from the Colon Cancer Family Registry
- (2012) Robyn L. Ward et al. GENETICS IN MEDICINE
- Unusual DNA mismatch repair–deficient tumors in Lynch syndrome: a report of new cases and review of the literature
- (2012) Yevgeniy Karamurzin et al. HUMAN PATHOLOGY
- Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study
- (2012) Aung Ko Win et al. JOURNAL OF CLINICAL ONCOLOGY
- Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome
- (2012) Christoph Engel et al. JOURNAL OF CLINICAL ONCOLOGY
- ColoSeq Provides Comprehensive Lynch and Polyposis Syndrome Mutational Analysis Using Massively Parallel Sequencing
- (2012) Colin C. Pritchard et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- A study of genomic instability in early preneoplastic colonic lesions
- (2012) A D Beggs et al. ONCOGENE
- BMPR1A Mutations in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency
- (2011) Taina T. Nieminen et al. GASTROENTEROLOGY
- Smoking Increases the Risk for Colorectal Adenomas in Patients With Lynch Syndrome
- (2011) Renate M. Winkels et al. GASTROENTEROLOGY
- Cancer Risks Associated With Germline Mutations in MLH1, MSH2, and MSH6 Genes in Lynch Syndrome
- (2011) Valérie Bonadona JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Determining the frequency of de novo germline mutations in DNA mismatch repair genes
- (2011) A. K. Win et al. JOURNAL OF MEDICAL GENETICS
- Current Hypotheses on How Microsatellite Instability Leads to Enhanced Survival of Lynch Syndrome Patients
- (2010) Kristen M. Drescher et al. Clinical & Developmental Immunology
- Immune evasion of microsatellite unstable colorectal cancers
- (2010) Matthias Kloor et al. INTERNATIONAL JOURNAL OF CANCER
- Germline hypermethylation ofMLH1andEPCAMdeletions are a frequent cause of Lynch syndrome
- (2009) Renée C. Niessen et al. GENES CHROMOSOMES & CANCER
- Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers
- (2009) Laura Baglietto et al. JNCI-Journal of the National Cancer Institute
- Differential cancer predisposition in Lynch syndrome: insights from molecular analysis of brain and urinary tract tumors
- (2008) A.H.S. Gylling et al. CARCINOGENESIS
- The Clinical Phenotype of Lynch Syndrome Due to Germ-Line PMS2 Mutations
- (2008) Leigha Senter et al. GASTROENTEROLOGY
- The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome
- (2008) Patrice Watson et al. INTERNATIONAL JOURNAL OF CANCER
- Large genomic rearrangements and germline epimutations in Lynch syndrome
- (2008) Annette Gylling et al. INTERNATIONAL JOURNAL OF CANCER
- Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1
- (2008) Marjolijn J L Ligtenberg et al. NATURE GENETICS
- Routinely assessed morphological features correlate with microsatellite instability status in endometrial cancer
- (2007) Jinru Shia et al. HUMAN PATHOLOGY
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