Article
Multidisciplinary Sciences
Gabriela E. Leghi, Ching T. Lai, Ardra Narayanan, Merryn J. Netting, Michael Dymock, Alethea Rea, Mary E. Wlodek, Donna T. Geddes, Beverly S. Muhlhausler
Summary: The study found that concentrations of fat, protein, and lactose in mature human milk did not significantly differ based on time of day, day of week, or which breast was used for collection, over a 3-week period.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Applied
Eric E. Newton, Asta H. Petursdottir, Stephane Beauclercq, James Clarke, Natasa Desnica, Sokratis Stergiadis
Summary: Based on previous studies, this study investigated the variations in macrominerals and trace elements concentrations in retail milk based on different production systems (conventional, organic, channel island) and seasons. The results showed that milk remained an excellent source of certain macrominerals and trace elements across different demographics, but the concentrations varied based on the production system and season. The variation in minerals concentration could have implications for the supply of certain nutrients in children and different consumer groups, and the seasonal variation was more significant than the variation associated with production system.
Article
Nutrition & Dietetics
Laurentya Olga, Janna A. van Diepen, Maciej Chichlowski, Clive J. Petry, Jacques Vervoort, David B. Dunger, Guus A. M. Kortman, Gabriele Gross, Ken K. Ong
Summary: This study investigated the origins and determining factors of butyrate in human milk and its influence on infant weight gain. The results showed that higher concentrations of butyrate in human milk were associated with lower infant weight and adiposity, especially in younger infants. Furthermore, the study found an inverse correlation between butyrate concentration and milk intake volume, suggesting a potential mechanism involving appetite regulation and modulation of milk intake.
Article
Chemistry, Applied
Sabrina H. Bilston-John, Ardra Narayanan, Ching Tat Lai, Alethea Rea, John Joseph, Donna T. Geddes
Summary: The study examined the daily and within-feed variations of macro- and trace-elements in human milk, finding significant differences in intake estimates when using morning pre-feed samples compared to measured 24-hour intake. Standardized sampling protocols with large sample volumes and multiple collections over 24-hours are recommended to provide a more accurate calculation of infant intake of macro- and trace-elements in human milk.
Article
Pharmacology & Pharmacy
Jana Kralovicova, Ales Bartunek, Jiri Hofmann, Tomas Krizek, Petr Kozlik, Jaroslava Rousarova, Pavel Rysanek, Martin Sima, Ondrej Slanar
Summary: The aim of this study is to compare the performance of parallel vs. cross-over design studies in describing the pharmacokinetics of a drug formulation. The results suggest that cross-over design provides more precise and accurate results compared to parallel design.
Review
Cell Biology
Somchai Chutipongtanate, Ardythe L. Morrow, David S. Newburg
Summary: Breastfeeding has numerous positive effects on the health of infants, including reducing the risk of diarrhea, respiratory diseases, otitis media, and chronic diseases later in life. In addition to the known components, human milk extracellular vesicles (hMEVs) containing miRNAs and proteins have been discovered to play a role in promoting infant growth and development. The composition of hMEVs can be influenced by the maternal health conditions.
Article
Cardiac & Cardiovascular Systems
Martin Berger, Nina Kumowski, Sam Straw, Marlo Verket, Nikolaus Marx, Klaus K. Witte, Katharina Schuett
Summary: In this study, the role of QRS width progression over time on the clinical status of heart failure patients was investigated. The results demonstrated that QRS width progression was associated with clinical deterioration, and it was independently predicted by plasma NT-pro-BNP levels and heart rate.
CLINICAL RESEARCH IN CARDIOLOGY
(2022)
Article
Management
Anne Zander, Stefan Nickel, Peter Vanberkel
Summary: This article focuses on balancing supply and demand for physicians and panel patients on a tactical level to ensure a manageable workload for the physician and access to care for patients. The proposed deterministic integer linear programs aim to minimize the deviation between expected panel workload and physician's capacity over time, considering future panel development. Through experiments with real-world data, the study shows that detailed classification of new patients can significantly reduce the expected differences between workload and capacity.
EUROPEAN JOURNAL OF OPERATIONAL RESEARCH
(2021)
Article
Allergy
Juan Carlos Cardet, Donghwa Kim, Eugene R. Bleecker, Thomas B. Casale, Elliot Israel, David Mauger, Deborah A. Meyers, Elizabeth Ampleford, Gregory A. Hawkins, Yaping Tu, Stephen B. Liggett, Victor E. Ortega
Summary: RGS2 promoter variation enhances bronchoconstrictive stimulation in human airway smooth muscle and is associated with asthma severity.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2022)
Article
Nutrition & Dietetics
Zhizhong Zhang, Mengmeng Wang, Shuai Yuan, Susanna C. Larsson, Xinfeng Liu
Summary: Genetically predicted higher milk intake is associated with a decreased risk of multiple sclerosis (MS) and Alzheimer's disease (AD) but an increased risk of Parkinson's disease (PD). However, genetically predicted milk intake is not associated with amyotrophic lateral sclerosis (ALS). Further research is needed to understand the underlying mechanisms.
Article
Geriatrics & Gerontology
Koen W. Streng, Hans L. Hillege, Jozine M. ter Maaten, Dirk J. van Veldhuisen, Kenneth Dickstein, Leong L. Ng, Nilesh J. Samani, Marco Metra, Piotr Ponikowski, John G. Cleland, Stefan D. Anker, Simon P. R. Romaine, Kevin Damman, Peter van der Meer, Chim C. Lang, Adriaan A. Voors
Summary: In patients with heart failure, lower estimated protein intake is associated with lower BMI and more signs of congestion, and independently associated with a higher risk of death.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Multidisciplinary Sciences
Catriona A. Morrison, Simon J. Butler, Jacquie A. Clark, Juan Arizaga, Oriol Balta, Jaroslav Cepak, Arantza Leal Nebot, Markus Piha, Kasper Thorup, Thomas Wenninger, Robert A. Robinson, Jennifer A. Gill
Summary: The variation in demographic rates across space and time can inform conservation policy and guide targeted actions to improve population dynamics. Understanding the specific conditions associated with low demographic rates is crucial for effective conservation strategies.
ROYAL SOCIETY OPEN SCIENCE
(2022)
Review
Physiology
Max C. Petersen, Molly R. Gallop, Stephany Flores Ramos, Amir Zarrinpar, Josiane L. Broussard, Maria Chondronikola, Amandine Chaix, Samuel Klein
Summary: This review discusses the effects and current research status of time-restricted eating (TRE) in the human body. By integrating the results of studies on rodent models and humans, it provides a framework for future research directions and identifies the current knowledge gaps.
PHYSIOLOGICAL REVIEWS
(2022)
Article
Multidisciplinary Sciences
Sally. L. L. Bornbusch, Mia. M. M. Keady, Michael. L. L. Power, Carly. R. R. Muletz-Wolz
Summary: Milk microbiomes play an important role in seeding infant gut microbiomes and immune development. This study investigated factors shaping milk microbiomes in three captive great ape species and found variations among host species, over lactation, and between housing facilities.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Civil
Maria Borjesson, Marco Kouwenhoven, Gerard de Jong, Andrew Daly
Summary: This paper examines the changes in the value of travel time (VTT) over time and finds that, despite a stable income level, the VTT generally declines. The study also reveals significant heterogeneity in the income elasticity and temporal development of VTT across different transportation modes and travel purposes, which may be attributed to changes in data and population.