Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

(2021) Paolo Armando Gagliardi et al.   DEVELOPMENTAL CELL

Calcium Wave Promotes Cell Extrusion

(2020) Yasuto Takeuchi et al.   CURRENT BIOLOGY

ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization

(2020) Naoya Hino et al.   DEVELOPMENTAL CELL

MAPK activity dynamics regulate non-cell autonomous effects of oncogene expression

(2020) Timothy J Aikin et al.   eLife

EPySeg: a coding-free solution for automated segmentation of epithelia using deep learning

(2020) Benoit Aigouy et al.   DEVELOPMENT

Apoptotic Fragmentation of Tricellulin

(2019) Susanne Janke et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular organization, regulation and function of tricellular junctions

(2019) Tomohito Higashi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cell Extrusion: A Stress-Responsive Force for Good or Evil in Epithelial Homeostasis

(2018) Shizue Ohsawa et al.   DEVELOPMENTAL CELL

A Switch-like Activation Relay of EGFR-ERK Signaling Regulates a Wave of Cellular Contractility for Epithelial Invagination

(2018) Yosuke Ogura et al.   DEVELOPMENTAL CELL

Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation

(2018) Eduardo Moreno et al.   CURRENT BIOLOGY

Cooperation of dual modes of cell motility promotes epithelial stress relaxation to accelerate wound healing

(2018) Michael F. Staddon et al.   PLoS Computational Biology

Feedback regulation of steady-state epithelial turnover and organ size

(2017) Jackson Liang et al.   NATURE

Transmission of cytokinesis forces via E-cadherin dilution and actomyosin flows

(2017) Diana Pinheiro et al.   NATURE

Epithelial cell extrusion: Pathways and pathologies

(2017) Swapna Aravind Gudipaty et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Deciphering the Complex Signaling Systems That Regulate Intestinal Epithelial Cell Death Processes and Shedding

(2017) Angela M. Patterson et al.   Frontiers in Immunology

Cell Competition: Mechanisms and Physiological Roles

(2016) Cristina Clavería et al.   Annual Review of Cell and Developmental Biology

Tissue Crowding Induces Caspase-Dependent Competition for Space

(2016) Romain Levayer et al.   CURRENT BIOLOGY

Death in the intestinal epithelium-basic biology and implications for inflammatory bowel disease

(2016) J. Magarian Blander   FEBS Journal

TissueMiner: A multiscale analysis toolkit to quantify how cellular processes create tissue dynamics

(2016) Raphaël Etournay et al.   eLife

Apico-basal forces exerted by apoptotic cells drive epithelium folding

(2015) Bruno Monier et al.   NATURE

Epithelial Cell Shedding and Barrier Function

(2014) J. M. Williams et al.   VETERINARY PATHOLOGY

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

Mechanics of Epithelial Tissue Homeostasis and Morphogenesis

(2013) C. Guillot et al.   SCIENCE

Visualization of caspase-3-like activity in cells using a genetically encoded fluorescent biosensor activated by protein cleavage

(2013) Jiao Zhang et al.   Nature Communications

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Live-cell delamination counterbalances epithelial growth to limit tissue overcrowding

(2012) Eliana Marinari et al.   NATURE

Altered Modes of Stem Cell Division Drive Adaptive Intestinal Growth

(2011) Lucy Erin O'Brien et al.   CELL

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila

(2010) Benoît Aigouy et al.   CELL

Efficient Ends-Out Gene Targeting In Drosophila

(2008) J. Huang et al.   GENETICS

Apoptotic Force and Tissue Dynamics During Drosophila Embryogenesis

(2008) Y. Toyama et al.   SCIENCE