期刊
CURRENT OPINION IN STRUCTURAL BIOLOGY
卷 68, 期 -, 页码 74-83出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2020.12.003
关键词
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资金
- PRIN 2017 'Glytunes' [2017XZ2ZBK]
- ERC under the European Union's Horizon 2020 research and innovation programme [851356]
- H2020 Marie Skodowska-Curie ITN 2018 'SweetCrossTalk' grant [814102]
- European Union
- Marie Curie Actions (MSCA) [814102] Funding Source: Marie Curie Actions (MSCA)
Analysis of the bacterial glycome is complex due to difficulties in structural and functional characterization, but advances in methods have significantly improved our understanding of microbial glycans.
The analysis of the bacterial glycome (glycomics) is among the complex 'omics' analysis owing to the inherent difficulties in structural and functional characterization of glycans. The complexity and variability of bacterial glycans, spanning from simple carbohydrates to complex glycolipids, glycopeptides and glycoproteins, make their study a challenging research area. The last two decades have witnessed tremendous advances and development of highly sophisticated methods, in combination with optimized protocols and hyphenate techniques for the understanding of structure, conformations, dynamics and organization of microbial glycans. We here present an overview of the novel approaches that have massively improved our understanding of the carbohydrate based world of bacteria.
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