Sensory cilia act as a specialized venue for regulated extracellular vesicle biogenesis and signaling

When Secretomes Meet Anthelmintics: Lessons for Therapeutic Interventions

(2021) Yovany Moreno et al.   TRENDS IN PARASITOLOGY

Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior

(2021) Stephan Raiders et al.   eLife

Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding

(2020) Jyothi S Akella et al.   eLife

Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling

(2020) Paurav B. Desai et al.   JOURNAL OF CELL BIOLOGY

Release and targeting of polycystin-2-carrying ciliary extracellular vesicles

(2020) Juan Wang et al.   CURRENT BIOLOGY

The tubulin code specializes neuronal cilia for extracellular vesicle release

(2020) Jyothi S. Akella et al.   Developmental Neurobiology

The molecular structure of mammalian primary cilia revealed by cryo-electron tomography

(2020) Petra Kiesel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cell type-specific structural plasticity of the ciliary transition zone in C. elegans

(2019) Jyothi S. Akella et al.   BIOLOGY OF THE CELL

Membrane retrieval, recycling and release pathways that organise and sculpt the ciliary membrane

(2019) Stephen P Carter et al.   CURRENT OPINION IN CELL BIOLOGY

Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model

(2019) Rebecca V. Walker et al.   Nature Communications

Cilia-based peptidergic signaling

(2019) Raj Luxmi et al.   PLOS BIOLOGY

Protein Amphipathic Helix Insertion: A Mechanism to Induce Membrane Fission

(2019) Mikhail A. Zhukovsky et al.   Frontiers in Cell and Developmental Biology

Endosome maturation factors Rabenosyn‐5/VPS45 and caveolin‐1 regulate ciliary membrane and polycystin‐2 homeostasis

(2018) Noémie Scheidel et al.   EMBO JOURNAL

Cell–cell communication via ciliary extracellular vesicles: clues from model systems

(2018) Juan Wang et al.   Essays in Biochemistry

Regulation of ciliary membrane protein trafficking and signalling by kinesin motor proteins

(2018) Stine Kjaer Morthorst et al.   FEBS Journal

Sexual Dimorphism and Sex Differences inCaenorhabditis elegansNeuronal Development and Behavior

(2018) Maureen M. Barr et al.   GENETICS

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sexual Dimorphism and Sex Differences inCaenorhabditis elegansNeuronal Development and Behavior

(2018) Maureen M. Barr et al.   GENETICS

Peripherin diverts ciliary ectosome release to photoreceptor disc morphogenesis

(2017) Robert S. Molday et al.   JOURNAL OF CELL BIOLOGY

Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release

(2017) Raquel Y. Salinas et al.   JOURNAL OF CELL BIOLOGY

Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks

(2017) Alexandre Paix et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling

(2017) Kenneth B. Schou et al.   Nature Communications

Ciliary Extracellular Vesicles: Txt Msg Organelles

(2016) Juan Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Comparative Analysis of Ciliary Membranes and Ectosomes

(2016) Huan Long et al.   CURRENT BIOLOGY

Proteomic Analysis of Isolated Ciliary Transition Zones Reveals the Presence of ESCRT Proteins

(2015) Dennis R. Diener et al.   CURRENT BIOLOGY

Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis

(2015) Juan Wang et al.   CURRENT BIOLOGY

Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis

(2015) Julie E. Maguire et al.   MOLECULAR BIOLOGY OF THE CELL

C. elegans Ciliated Sensory Neurons Release Extracellular Vesicles that Function in Animal Communication

(2014) Juan Wang et al.   CURRENT BIOLOGY

Identification of Biomarkers for PKD1 Using Urinary Exosomes

(2014) M. C. Hogan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Compartments within a compartment

(2014) Oliver E Blacque et al.   Organogenesis

Tetraspanins in Extracellular Vesicle Formation and Function

(2014) Zoraida Andreu et al.   Frontiers in Immunology

The Cilium Secretes Bioactive Ectosomes

(2013) Christopher R. Wood et al.   CURRENT BIOLOGY

Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease

(2013) Ming Ma et al.   NATURE GENETICS

Kinesin-3 KLP-6 Regulates Intraflagellar Transport in Male-Specific Cilia of Caenorhabditis elegans

(2011) Natalia S. Morsci et al.   CURRENT BIOLOGY

Patterns of kinesin evolution reveal a complex ancestral eukaryote with a multifunctional cytoskeleton

(2010) Bill Wickstead et al.   BMC EVOLUTIONARY BIOLOGY

Functional Specialization of Sensory Cilia by an RFX Transcription Factor Isoform

(2010) J. Wang et al.   GENETICS

The CIL-1 PI 5-Phosphatase Localizes TRP Polycystins to Cilia and Activates Sperm in C. elegans

(2009) Young-Kyung Bae et al.   CURRENT BIOLOGY

Characterization of PKD Protein-Positive Exosome-Like Vesicles

(2009) M. C. Hogan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TheCaenorhabditis elegansnephrocystins act as global modifiers of cilium structure

(2008) Andrew R. Jauregui et al.   JOURNAL OF CELL BIOLOGY