Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis

Dietary intake of high-dose biotin inhibits spermatogenesis in young rats

(2015) Hiromi Sawamura et al.   CONGENITAL ANOMALIES

Beta-interferon exposure and onset of secondary progressive multiple sclerosis

(2015) T. Zhang et al.   EUROPEAN JOURNAL OF NEUROLOGY

Hematopoietic Stem Cell Transplantation for MS

(2015) Stephen L. Hauser   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Major involvement of Na+-dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells

(2015) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives

(2015) Daniel Ontaneda et al.   LANCET NEUROLOGY

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Dietary intake of high-dose biotin inhibits spermatogenesis in young rats

(2015) Hiromi Sawamura et al.   CONGENITAL ANOMALIES

High doses of biotin in chronic progressive multiple sclerosis: A pilot study

(2015) Frédéric Sedel et al.   Multiple Sclerosis and Related Disorders

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Multiple sclerosis: Prospects and promise

(2013) Stephen L. Hauser et al.   ANNALS OF NEUROLOGY

Long-term impact of interferon beta-1b in patients with CIS: 8-year follow-up of BENEFIT

(2013) G. Edan et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Effect of dronabinol on progression in progressive multiple sclerosis (CUPID): a randomised, placebo-controlled trial

(2013) John Zajicek et al.   LANCET NEUROLOGY

LINGO-1, a Transmembrane Signaling Protein, Inhibits Oligodendrocyte Differentiation and Myelination through Intercellular Self-interactions

(2012) Scott Jepson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Time to secondary progression in patients with multiple sclerosis who were treated with first generation immunomodulating drugs

(2012) H Tedeholm et al.   Multiple Sclerosis Journal

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

Biotin-responsive basal ganglia disease revisited: Clinical, radiologic, and genetic findings

(2012) B. Tabarki et al.   NEUROLOGY

Biotin interference on TSH and free thyroid hormone measurement

(2012) Jeffrey Sung-Shing Kwok et al.   PATHOLOGY

Positive and negative interference in immunoassays following biotin ingestion: a pharmacokinetic study

(2012) Nilika G. Wijeratne et al.   PATHOLOGY

A wide spectrum of clinical and brain MRI findings in patients with SLC19A3mutations

(2011) Kenichiro Yamada et al.   BMC Medical Genetics

The neurology of biotinidase deficiency

(2011) Barry Wolf   MOLECULAR GENETICS AND METABOLISM

A phase III study evaluating the efficacy and safety of MBP8298 in secondary progressive MS

(2011) M. S. Freedman et al.   NEUROLOGY

Biotin-Responsive Basal Ganglia Disease in Ethnic Europeans With Novel SLC19A3 Mutations

(2010) Rabab Debs et al.   ARCHIVES OF NEUROLOGY

Analysis of clinical outcomes according to original treatment groups 16 years after the pivotal IFNB-1b trial

(2010) G. C. Ebers et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Clinical issues and frequent questions about biotinidase deficiency

(2010) Barry Wolf   MOLECULAR GENETICS AND METABOLISM

Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial

(2009) Kathleen Hawker et al.   ANNALS OF NEUROLOGY

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

Sustained-release oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial

(2009) Andrew D Goodman et al.   LANCET

Biotin-Responsive Basal Ganglia Disease: Case Report and Review of the Literature

(2009) T. El-Hajj et al.   NEUROPEDIATRICS