Nuclear factor-kappa B and its role in inflammatory lung disease

Liu Shen capsule shows antiviral and anti-inflammatory abilities against novel coronavirus SARS-CoV-2 via suppression of NF-κB signaling pathway

(2020) Qinhai Ma et al.   PHARMACOLOGICAL RESEARCH

Phillyrin (KD-1) exerts anti-viral and anti-inflammatory activities against novel coronavirus (SARS-CoV-2) and human coronavirus 229E (HCoV-229E) by suppressing the nuclear factor kappa B (NF-κB) signaling pathway

(2020) Qinhai Ma et al.   PHYTOMEDICINE

Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-κB/cyclin D1 pathway

(2020) Lin Mei et al.   Nature Communications

Mechanisms of Virus-Induced Airway Immunity Dysfunction in the Pathogenesis of COPD Disease, Progression, and Exacerbation

(2020) Hong Guo-Parke et al.   Frontiers in Immunology

Beta‐catenin non‐canonical pathway: A potential target for inflammatory and hyperproliferative state via expression of transglutaminase 2 in psoriatic skin keratinocyte

(2020) Gaurav Gupta et al.   Dermatologic Therapy

Taming the cytokine storm: repurposing montelukast for the attenuation and prophylaxis of severe COVID-19 symptoms

(2020) Nitesh Sanghai et al.   DRUG DISCOVERY TODAY

Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation

(2019) Venkatesh Pooladanda et al.   Cell Death & Disease

Montelukast, Leukotriene Inhibitor, Reduces LPS-Induced Acute Lung Inflammation and Human Neutrophil Activation

(2019) Jaime Eduardo Davino-Chiovatto et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Experimental pulmonary fibrosis was suppressed by microRNA-506 through NF-kappa-mediated apoptosis and inflammation

(2019) Min Zhu et al.   CELL AND TISSUE RESEARCH

Ergosterol attenuates cigarette smoke extract-induced COPD by modulating inflammation, oxidative stress and apoptosis in vitro and in vivo

(2019) Xiao Sun et al.   CLINICAL SCIENCE

Chrysophanol attenuates airway inflammation and remodeling through nuclear factor‐kappa B signaling pathway in asthma

(2019) Guihua Song et al.   PHYTOTHERAPY RESEARCH

Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense

(2019) Mengfei Chen et al.   Cell Stem Cell

Vaporized perfluorocarbon inhalation attenuates primary blast lung injury in canines by inhibiting mitogen-activated protein kinase/nuclear factor-κB activation and inducing nuclear factor, erythroid 2 like 2 pathway

(2019) Zhaorui Zhang et al.   TOXICOLOGY LETTERS

Isoliquiritigenin protects against sepsis-induced lung and liver injury by reducing inflammatory responses

(2018) Xiong Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miRNA-1246 suppresses acute lung injury-induced inflammation and apoptosis via the NF-κB and Wnt/β-catenin signal pathways

(2018) Tao Suo et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA-27a alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis through modulating TLR4/MyD88/NF-κB pathway

(2018) MinJie Ju et al.   CELL CYCLE

Nuclear Receptor 77

(2018) Asoka Banno et al.   AMERICAN JOURNAL OF PATHOLOGY

Lung cancer–associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell–immune cell cross-talk

(2017) Soni Savai Pullamsetti et al.   Science Translational Medicine

Emodin suppresses LPS-induced inflammation in RAW264.7 cells through a PPARγ-dependent pathway

(2016) Tao Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathway

(2016) Jie Zheng et al.   Scientific Reports

Understanding ARDS-associated fibroproliferation

(2015) Gianfranco Umberto Meduri et al.   INTENSIVE CARE MEDICINE

Cellular and molecular mechanisms of chronic rhinosinusitis and potential therapeutic strategies: review on cytokines, nuclear factor kappa B and transforming growth factor beta

(2015) N T Phan et al.   JOURNAL OF LARYNGOLOGY AND OTOLOGY

Nuclear factor-kappa-B signaling in lung development and disease: One pathway, numerous functions

(2014) Cristina M. Alvira   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Novel lung adenocarcinoma and nuclear factor-kappa B (NF-κB) inhibitors: Synthesis and evaluation of lantadene congeners

(2014) Sharad Kumar Suthar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Salidroside Attenuates Allergic Airway Inflammation Through Negative Regulation of Nuclear Factor-Kappa B and p38 Mitogen–Activated Protein Kinase

(2014) Guang Hai Yan et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

(2013) Anu Kauppinen et al.   CELLULAR SIGNALLING

Inhibition of NF- B-Mediated Inflammation in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice Increases Survival

(2013) M. L. DeDiego et al.   JOURNAL OF VIROLOGY

Tumor necrosis factor-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease

(2013) M R Starkey et al.   Mucosal Immunology

Nuclear Factor κ-B Is Activated in the Pulmonary Vessels of Patients with End-Stage Idiopathic Pulmonary Arterial Hypertension

(2013) Laura C. Price et al.   PLoS One

A Pro-Inflammatory Role for Nuclear Factor Kappa B in Childhood Obstructive Sleep Apnea Syndrome

(2013) Lee P. Israel et al.   SLEEP

Insertion of a nuclear factor kappa B DNA nuclear-targeting sequence potentiates suicide gene therapy efficacy in lung cancer cell lines

(2012) F Cramer et al.   CANCER GENE THERAPY

Nuclear Factor Kappa B: A Pro-Inflammatory, Transcription Factor−Mediated Signalling Pathway in Lung Carcinogenesis and Its Inhibition By Nonsteroidal Anti-Inflammatory Drugs

(2012) Shruti Setia et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Sedative, antiepileptic and antipsychotic effects of Viscum album L. (Loranthaceae) in mice and rats

(2012) Gaurav Gupta et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nuclear Factor-Kappa B Mediates One-Lung Ventilation-Induced Acute Lung Injury in Rabbits

(2012) Zhijian You et al.   JOURNAL OF INVESTIGATIVE SURGERY

The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation

(2012) Laura Tornatore et al.   TRENDS IN CELL BIOLOGY

Nuclear Factor-κB: a Key Regulator in Health and Disease of Lungs

(2011) Sanjay Batra et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation

(2011) Chien-Sheng Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IκB kinase–driven nuclear factor-κB activation in patients with asthma and chronic obstructive pulmonary disease

(2011) Rosalia Gagliardo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL