期刊
CEPHALALGIA
卷 42, 期 3, 页码 266-272出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/03331024211038654
关键词
COVID-19; vaccination; migraine
资金
- JSPS KAKENHI [19K16989]
- Grants-in-Aid for Scientific Research [19K16989] Funding Source: KAKEN
In a questionnaire survey conducted from April to May 2021, participants with a history of migraine and non-migrainous headache were found to have a higher incidence of headaches after COVID-19 vaccination compared to healthy controls.
Background: Headache is an adverse event of coronavirus 2019 (COVID-19) vaccination. Whether patients with history of headache suffer more from vaccination-induced headaches is unknown. We aimed to uncover if headache patients develop more headaches after COVID-19 mRNA vaccination than healthy controls. Methods: We performed a questionnaire survey for nursing staff in our hospital from April to May 2021. Based on baseline characteristics, we divided the participants into migraine, non-migrainous headache, and healthy control, and examined the occurrence and features of headache after COVID-19 vaccinations. Results: We included 171 participants (15.2% migraine and 24.6% non-migrainous headache). Headache incidence after vaccinations was significantly higher in the migraine (69.2%) and non-migrainous headache (71.4%) groups than in the healthy control (37.9%) group. The incidence of headaches was significantly higher after the second dose compared to the first (45.6% vs. 20.5%). Conclusion: Migraineurs and non-migrainous headache participants developed more headaches compared to the healthy controls after COVID-19 vaccination.
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