Patients with COVID-19: in the dark-NETs of neutrophils

The interplay between neutrophils, complement, and microthrombi in COVID-19

(2021) Yu Zuo et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Genome‐wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID‐19

(2021) Michael J. Corley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vascular Endothelial Damage in the Pathogenesis of Organ Injury in Severe COVID-19

(2021) Annabelle Dupont et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

COVID-19-associated liver injury: from bedside to bench

(2021) Dongxiao Li et al.   JOURNAL OF GASTROENTEROLOGY

Neutrophils set extracellular traps to injure lungs in COVID-19

(2021) Narasaraju Teluguakula   JOURNAL OF INFECTIOUS DISEASES

Potential mechanisms of cerebrovascular diseases in COVID-19 patients

(2021) Manxue Lou et al.   JOURNAL OF NEUROVIROLOGY

Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia

(2021) Ivan O. Rosas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

(2021)   NEW ENGLAND JOURNAL OF MEDICINE

C-Reactive Protein Triggers Cell Death in Ischemic Cells

(2021) Ahmed Sheriff et al.   Frontiers in Immunology

Neutrophil Extracellular Traps in Coronavirus Disease-19-Associated Ischemic Stroke: A Novel Avenue in Neuroscience

(2021) Tjokorda Istri Pramitasuri et al.   Experimental Neurobiology

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

(2021) Bruce A. Rosa et al.   Communications Biology

Towards better understanding of the heparin role in NETosis: Feasibility of using native mass spectrometry to monitor interactions of neutrophil elastase with heparin oligomers

(2021) Chendi Niu et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Vasculitis and Neutrophil Extracellular Traps in Lungs of Golden Syrian Hamsters With SARS-CoV-2

(2021) Kathrin Becker et al.   Frontiers in Immunology

Neutrophil Extracellular Traps: A Potential Therapeutic Target in MPO-ANCA Associated Vasculitis?

(2021) Kim M. O'Sullivan et al.   Frontiers in Immunology

Circulating Nucleosomes as Potential Markers to Monitor COVID-19 Disease Progression

(2021) Etienne Cavalier et al.   Frontiers in Molecular Biosciences

“HIT”ing back against NETs

(2020) Shadi Swaidani et al.   BLOOD

Programmed ‘disarming’ of the neutrophil proteome reduces the magnitude of inflammation

(2020) Jose M. Adrover et al.   NATURE IMMUNOLOGY

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

COVID-19 Autopsies, Oklahoma, USA

(2020) Lisa M Barton et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19

(2020) Huilan Zhang et al.   ANNALS OF INTERNAL MEDICINE

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases

(2020) Renato G. S. Chirivi et al.   Cellular & Molecular Immunology

Complement activation in patients with COVID-19: A novel therapeutic target

(2020) Massimo Cugno et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care

(2020) Luca Quartuccio et al.   JOURNAL OF CLINICAL VIROLOGY

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

(2020) Betsy J. Barnes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19

(2020) Marisa Dolhnikoff et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Heparin resistance in COVID-19 patients in the intensive care unit

(2020) D. White et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Acute kidney injury in patients hospitalized with COVID-19

(2020) Jamie S. Hirsch et al.   KIDNEY INTERNATIONAL

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

Pathological study of the 2019 novel coronavirus disease (COVID-19) through postmortem core biopsies

(2020) Sufang Tian et al.   MODERN PATHOLOGY

Mouse models of neutropenia reveal progenitor-stage-specific defects

(2020) David E. Muench et al.   NATURE

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

(2020) Jun Jacob Hu et al.   NATURE IMMUNOLOGY

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19

(2020) Joshua Geleris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiorgan and Renal Tropism of SARS-CoV-2

(2020) Victor G. Puelles et al.   NEW ENGLAND JOURNAL OF MEDICINE

NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture

(2020) Hawa Racine Thiam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases

(2020) Cynthia Magro et al.   Translational Research

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19

(2020) Tao Wang et al.   Lancet Haematology

Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19

(2020) Xiaoyan Liu et al.   Acta Pharmaceutica Sinica B

Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome

(2020) Elizabeth A Middleton et al.   BLOOD

Platelet Gene Expression and Function in COVID-19 Patients

(2020) Bhanu Kanth Manne et al.   BLOOD

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

(2020) Jonas Schulte-Schrepping et al.   CELL

Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19

(2020) Aymeric Silvin et al.   CELL

Immunothrombotic Dysregulation in COVID-19 Pneumonia is Associated with Respiratory Failure and Coagulopathy

(2020) Leo Nicolai et al.   CIRCULATION

The first case of COVID-19 treated with the complement C3 inhibitor AMY-101

(2020) Sara Mastaglio et al.   CLINICAL IMMUNOLOGY

Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor

(2020) Immanuel Kwok et al.   IMMUNITY

Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19

(2020) Samia Arshad et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

COVID-19: Complement, Coagulation, and Collateral Damage

(2020) Martin W. Lo et al.   JOURNAL OF IMMUNOLOGY

Cytokine storm and leukocyte changes in mild versus severe SARS‐CoV‐2 infection: Review of 3939 COVID‐19 patients in China and emerging pathogenesis and therapy concepts

(2020) Jin Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lung Protection by Cathepsin C Inhibition: A New Hope for COVID-19 and ARDS?

(2020) Brice Korkmaz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

(2020) Xuemei Xie et al.   NATURE IMMUNOLOGY

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

(2020) Aaron J. Wilk et al.   NATURE MEDICINE

Extrapulmonary manifestations of COVID-19

(2020) Aakriti Gupta et al.   NATURE MEDICINE

A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19

(2020) David R. Boulware et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Selective C‐reactive protein apheresis for Covid‐19 patients suffering from organ damage

(2020) Stefan Kayser et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial

(2020) J. P. Desilles et al.   Trials

Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion

(2020) David Simon et al.   Nature Communications

Combination of Ruxolitinib and Eculizumab for Treatment of Severe SARS-CoV-2-Related Acute Respiratory Distress Syndrome: A Controlled Study

(2020) Valentina Giudice et al.   Frontiers in Pharmacology

Neutrophils as Main Players of Immune Response towards Nondegradable Nanoparticles

(2020) Rostyslav Bilyy et al.   Nanomaterials

Coagulation abnormalities and thrombosis in patients with COVID-19

(2020) Marcel Levi et al.   Lancet Haematology

Vascular occlusion by neutrophil extracellular traps in COVID-19

(2020) Moritz Leppkes et al.   EBioMedicine

New (re)purpose for an old drug: purinergic modulation may extinguish the COVID-19 thromboinflammatory firestorm

(2020) Yogendra Kanthi et al.   JCI Insight

Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis

(2020) Carmelo Carmona-Rivera et al.   JCI Insight

Immunopathology of Hyperinflammation in COVID-19

(2020) Joshua N. Gustine et al.   AMERICAN JOURNAL OF PATHOLOGY

Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia

(2020) Francesco Taus et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm

(2020) Yun Young Lee et al.   BIOMATERIALS

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

(2020) Eugenio D. Hottz et al.   BLOOD

Platelets Can Associate with SARS-Cov-2 RNA and Are Hyperactivated in COVID-19

(2020) Younes Zaid et al.   CIRCULATION RESEARCH

Anti-complement C5 therapy with eculizumab in three cases of critical COVID-19

(2020) Jeffrey Laurence et al.   CLINICAL IMMUNOLOGY

COVID-19 is, in the end, an endothelial disease

(2020) Peter Libby et al.   EUROPEAN HEART JOURNAL

Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow

(2020) Huy Q. Dinh et al.   IMMUNITY

High dose subcutaneous Anakinra to treat acute respiratory distress syndrome secondary to cytokine storm syndrome among severely ill COVID-19 patients

(2020) Enrique Iglesias-Julián et al.   JOURNAL OF AUTOIMMUNITY

Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

(2020) Panagiotis Skendros et al.   JOURNAL OF CLINICAL INVESTIGATION

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

(2020) Flavio Protasio Veras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil calprotectin identifies severe pulmonary disease in COVID‐19

(2020) Hui Shi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Anticoagulation, Bleeding, Mortality, and Pathology in Hospitalized Patients With COVID-19

(2020) Girish N. Nadkarni et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

SARS-CoV-2 renal tropism associates with acute kidney injury

(2020) Fabian Braun et al.   LANCET

Preventing the development of severe CoVID 19 by modifying immunothrombosis

(2020) Gerwyn Morris et al.   LIFE SCIENCES

Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series

(2020) Andrew G. Weber et al.   MOLECULAR MEDICINE

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function

(2020) Emma S. Winkler et al.   NATURE IMMUNOLOGY

Immunothrombosis and thromboinflammation in host defense and disease

(2020) Kimberly Martinod et al.   PLATELETS

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia

(2020) Olivier Hermine et al.   JAMA Internal Medicine

Beneficial non-anticoagulant mechanisms underlying heparin treatment of COVID-19 patients

(2020) Baranca Buijsers et al.   EBioMedicine

Risk of stroke in hospitalized SARS-CoV-2 infected patients: A multinational study

(2020) Shima Shahjouei et al.   EBioMedicine

Fostamatinib Inhibits Neutrophils Extracellular Traps Induced by COVID-19 Patient Plasma: A Potential Therapeutic

(2020) Jeffrey R Strich et al.   JOURNAL OF INFECTIOUS DISEASES

Neutrophil more than platelet activation associates with thrombotic complications in COVID-19 patients

(2020) E Petito et al.   JOURNAL OF INFECTIOUS DISEASES

Thromboinflammation in COVID‐19: Can α 2 ‐macroglobulin help to control the fire?

(2020) Rainer Seitz et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19

(2020) Xiyuan Bai et al.   MEDICAL HYPOTHESES

How to bridle a neutrophil

(2020) Andrea Rubio-Ponce et al.   CURRENT OPINION IN IMMUNOLOGY

Selective C‐reactive protein‐apheresis in patients

(2019) Wolfgang Ries et al.   THERAPEUTIC APHERESIS AND DIALYSIS

Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2

(2019) Carmelo Carmona-Rivera et al.   BLOOD

ENTPD-1 disrupts inflammasome IL-1β–driven venous thrombosis

(2019) Vinita Yadav et al.   JOURNAL OF CLINICAL INVESTIGATION

Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasion

(2019) Victoria L. Stefanelli et al.   MATRIX BIOLOGY

The Neutrophil Life Cycle

(2019) Andrés Hidalgo et al.   TRENDS IN IMMUNOLOGY

Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome

(2019) Ramadan A. Ali et al.   Nature Communications

Neutrophil Extracellular Traps Initiate Gallstone Formation

(2019) Luis E. Muñoz et al.   IMMUNITY

Heparin improves alveolarization and vascular development in hyperoxia-induced bronchopulmonary dysplasia by inhibiting neutrophil extracellular traps

(2019) Yuanyuan Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The double-edged role of neutrophil extracellular traps in inflammation

(2019) Maximilien Euler et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

(2019) José M. Adrover et al.   IMMUNITY

Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation

(2019) Stefanie Gößwein et al.   Frontiers in Immunology

The Role of Extracellular Histones in Influenza Virus Pathogenesis

(2018) Harshini K. Ashar et al.   AMERICAN JOURNAL OF PATHOLOGY

Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes

(2018) Min-Han Lin et al.   ANTIVIRAL RESEARCH

NETosis, complement, and coagulation: a triangular relationship

(2018) Cynthia M. de Bont et al.   Cellular & Molecular Immunology

Inhibition of peptidylarginine deiminase alleviates LPS-induced pulmonary dysfunction and improves survival in a mouse model of lethal endotoxemia

(2018) Yingjian Liang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

(2018) Maximilien Evrard et al.   IMMUNITY

Entamoeba histolytica Trophozoites Induce a Rapid Non-classical NETosis Mechanism Independent of NOX2-Derived Reactive Oxygen Species and PAD4 Activity

(2018) César Díaz-Godínez et al.   Frontiers in Cellular and Infection Microbiology

Cleaved N-terminal histone tails distinguish between NADPH oxidase (NOX)-dependent and NOX-independent pathways of neutrophil extracellular trap formation

(2018) Elmar Pieterse et al.   ANNALS OF THE RHEUMATIC DISEASES

Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases

(2018) Jonas Hahn et al.   FASEB JOURNAL

Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production

(2018) Poorya Amini et al.   Nature Communications

Respiratory Syncytial Virus induces the classical ROS-dependent NETosis through PAD-4 and necroptosis pathways activation

(2018) Stéfanie P. Muraro et al.   Scientific Reports

Extracellular traps in kidney disease

(2018) Daigo Nakazawa et al.   KIDNEY INTERNATIONAL

Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation

(2017) Nina Germic et al.   IMMUNOLOGY

Diagnostic potential of NETosis-derived products for disease activity, atherosclerosis and therapeutic effectiveness in Rheumatoid Arthritis patients

(2017) C. Pérez-Sánchez et al.   JOURNAL OF AUTOIMMUNITY

ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation

(2017) Darko Stojkov et al.   JOURNAL OF CELL BIOLOGY

Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation

(2017) Akrivi Chrysanthopoulou et al.   JOURNAL OF PATHOLOGY

Visualizing the function and fate of neutrophils in sterile injury and repair

(2017) Jing Wang et al.   SCIENCE

Host DNases prevent vascular occlusion by neutrophil extracellular traps

(2017) Miguel Jiménez-Alcázar et al.   SCIENCE

Granulopoiesis and granules of human neutrophils

(2016) Jack B. Cowland et al.   IMMUNOLOGICAL REVIEWS

Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis

(2016) K. Martinod et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Angiocrine functions of organ-specific endothelial cells

(2016) Shahin Rafii et al.   NATURE

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

The role of neutrophils and NETosis in autoimmune and renal diseases

(2016) Sarthak Gupta et al.   Nature Reviews Nephrology

Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation

(2016) Luis E. Muñoz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

(2016) Moritz Leppkes et al.   Nature Communications

Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction

(2016) Yasuko Furumoto et al.   Arthritis & Rheumatology

PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling

(2015) Jyaysi Desai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx

(2015) David Nobuhiro Douda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

(2015) Elzbieta Kolaczkowska et al.   Nature Communications

Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2

(2014) Carmelo Carmona-Rivera et al.   ANNALS OF THE RHEUMATIC DISEASES

Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils

(2014) I. Neeli et al.   JOURNAL OF IMMUNOLOGY

Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates

(2014) Sigrun Lange et al.   JOURNAL OF NEUROCHEMISTRY

Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps

(2014) N. Maugeri et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Neutrophils scan for activated platelets to initiate inflammation

(2014) Vinatha Sreeramkumar et al.   SCIENCE

Neutrophil Extracellular Trap-Derived Enzymes Oxidize High-Density Lipoprotein: An Additional Proatherogenic Mechanism in Systemic Lupus Erythematosus

(2014) Carolyne K. Smith et al.   Arthritis & Rheumatology

Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance

(2013) María Casanova-Acebes et al.   CELL

Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps

(2013) Craig N. Jenne et al.   Cell Host & Microbe

Antibodies Mediate Formation of Neutrophil Extracellular Traps in the Middle Ear and Facilitate Secondary Pneumococcal Otitis Media

(2013) Kirsty R. Short et al.   INFECTION AND IMMUNITY

The role of heparanase and the endothelial glycocalyx in the development of proteinuria

(2013) Marjolein Garsen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis

(2012) Braedon McDonald et al.   Cell Host & Microbe

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil Extracellular Trap-Associated Protein Activation of the NLRP3 Inflammasome Is Enhanced in Lupus Macrophages

(2012) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis

(2012) Eric P Schmidt et al.   NATURE MEDICINE

Elastase-mediated Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein at Discrete Sites within the S2 Domain

(2010) Sandrine Belouzard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE