Article
Engineering, Environmental
Suparat Rukchonlatee, Punnama Siriphannon
Summary: Montmorillonite/tripolyphosphate crosslinked chitosan containing potassium nitrate nanocomposites were synthesized by a simple impregnation method. The nanocomposites consisted of K+ and NO3- ions embedded in crosslinked chitosan, intercalated in the structure of montmorillonite. The nanocomposites showed controlled release of K+ and NO3- ions, with prolonged release times in the presence of higher TPP concentration.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Microbiology
Rachid Lahlali, Said Ezrari, Nabil Radouane, Jihane Kenfaoui, Qassim Esmaeel, Hajar El Hamss, Zineb Belabess, Essaid Ait Barka
Summary: The increase in world population has resulted in higher demands for agricultural products. However, the use of chemical pesticides has caused concerns over their impact on human health and the environment. As a result, researchers have turned to biological controls using beneficial microorganisms, but the development of biofungicides has faced challenges. This review focuses on the gap between the screening of biological control agents and the availability of marketed products, and highlights the obstacles in terms of efficacy and legislation procedures.
Article
Chemistry, Multidisciplinary
Zhiwen Wang, Yu Li, Borui Zhang, Xiang Gao, Mengru Shi, Sicong Zhang, Shan Zhong, Yang Zheng, Xili Liu
Summary: Spray-induced gene silencing (SIGS) is an attractive method for plant protection, but the limited uptake efficiency of double-stranded RNA (dsRNA) has hindered its application against Phytophthora pathogens. In this study, functionalized carbon dots (CDs) were used to enhance the control efficacy of dsRNA against Phytophthora infestans, Phytophthora sojae, and P. capsici. The synergistic effect is attributed to improved dsRNA stability and internalization. Additionally, this is the first report of utilizing a nano-delivery system to improve the effect of SIGS against Phytophthora pathogens.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Mohamed S. El-Okaily, Amira M. EL-Rafei, Mona Basha, Nour T. Abdel Ghani, Mayyada M. H. El-Sayed, Asim Bhaumik, Amany A. Mostafa
Summary: Nano-fiber composites consisting of a blend of polyvinyl alcohol (PVA) and chitosan (CS) with different weight ratios of nano-bioactive glass (BG) were prepared by electrospinning. The drug release efficiency of the developed nano-fiber composites with BG was enhanced and sustained, with the release pattern taking place through a two-stage intra-particle diffusion mechanism. The presence of BG in the nano-fibers significantly retarded the drug release profile compared to their BG-free counterparts.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Yi Zhou, Jiyingzi Wu, Jun Zhou, Sukun Lin, Dongmei Cheng
Summary: Controlling the release of pesticides in response to environmental stimuli by encapsulating them in nanoparticles is a feasible approach. In this study, pH-responsive release nanoparticles were prepared and showed good washout resistance and wettability properties. The nanoparticles had adjustable controlled-release characteristics and enhanced the inhibitory effect under acidic conditions, achieving better control and longer duration compared to aqueous solution.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Microbiology
Muhammad M. Raza, Daniel P. Bebber
Summary: Global food security is threatened by climate change, with rising temperatures identified as the primary driver of disease impact. Process-based models indicate that rising temperatures will lead to shifts in disease pressure, while experimental studies suggest that rising atmospheric CO2 will exacerbate disease impacts.
CURRENT OPINION IN MICROBIOLOGY
(2022)
Review
Biology
Mohamed T. El-Saadony, Ameina S. ALmoshadak, Manal E. Shafi, Najah M. Albaqami, Ahmed M. Saad, Amira M. El-Tahan, El-Sayed M. Desoky, Ahmed S. M. Elnahal, Aisha Almakas, Taia A. Abd El-Mageed, Ayman E. Taha, Ahmed S. Elrys, Ayman M. Helmy
Summary: Nanotechnology in agriculture offers potential for increased production quality and reduced environmental impact. Nano-fertilizers and pesticides can improve nutrient efficiency and enhance plant resistance to abiotic stress and heavy metal toxicity.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Polymer Science
Mengting Du, Ying Yi, Yihua Yin, Zhi Cai, Weiquan Cai, Junli Li, Guanghua He, Jingli Zhang
Summary: Faced with drug resistance and environmental pollution, there is an urgent need for new green and efficient pesticides. A novel antibacterial nano-system for plant protection based on photodynamic action was developed by grafting hematoporphyrin onto modified chitosan. The self-quenching effect of grafted hematoporphyrin prevents photodegradation and enhances photostability. Enzyme stimulation triggers the release of hematoporphyrin, providing efficient photodynamic effect against bacterial infection.
EUROPEAN POLYMER JOURNAL
(2023)
Review
Chemistry, Multidisciplinary
Graciela Dolores Avila-Quezada, Avinash P. Ingle, Patrycja Golinska, Mahendra Rai
Summary: Nano-fertilizers are emerging as a promising research field in agriculture, offering a novel way to optimize nutrient supply and increase global food production. The use of nanocarriers can reduce the amount of active chemicals deposited in plants and provide slow-release nutrients. This review addresses the potential benefits, synthesis, mode of entry, mechanisms of action, and fate of nanomaterials in soil for NFs in agriculture.
NANOTECHNOLOGY REVIEWS
(2022)
Review
Agronomy
Guido Fellet, Laura Pilotto, Luca Marchiol, Enrico Braidot
Summary: The Green New Deal calls for a profound transformation of the agricultural sector, with the introduction of nanotechnologies to improve nutrient delivery and efficiency, in order to reduce environmental pollution and water eutrophication.
Article
Nanoscience & Nanotechnology
Sreekanth Reddy Obireddy, Wing-Fu Lai
Summary: In this study, a new type of nanocomposites was designed as a carrier for controlled delivery of bioactive agents. The nanocomposites showed pH-responsive behavior, reactive oxygen species (ROS)-generating capacity, and cell type-dependent toxicity. This research demonstrates the high potential of the nanocomposites for use in bioactive agent delivery and their potential as pH-responsive carriers for therapeutic applications.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Polymer Science
Mohamed Gouda, Hairul-Islam Mohamed Ibrahim, Amr Negm
Summary: A biologically active agent, named Zn-BTC@CS, based on a Zn-1,3,5-benzen tricarboxylic acid (Zn-BTC) framework incorporated into a chitosan (CS) biopolymer was successfully synthesized using a microwave irradiation technique. The synthesized Zn-BTC@CS showed a smooth surface morphology and a particle size diameter ranging from 20 to 40 nm. It exhibited anticancer efficacy against lung and colon cancer cell lines by inhibiting proliferation, inducing apoptosis, and inhibiting migration.
Review
Biotechnology & Applied Microbiology
Yazid Zaiki, Athirah Iskandar, Tin Wui Wong
Summary: Chitosan, as a biotechnological derivative of chitin, has various pharmaceutical and biomedical applications. It can encapsulate and deliver cancer therapeutics with specific drug targeting at the tumor microenvironment, enhancing cancer cytotoxic drug actions. To minimize off-target effects and drug-related adverse reactions, it is clinically necessary to achieve highly targeted drug delivery at the lowest possible drug doses.
BIOTECHNOLOGY ADVANCES
(2023)
Article
Plant Sciences
Shokoofeh Hajihashemi, Shadi Kazemi
Summary: The physiological mechanisms through which a nano-chitosan-encapsulated nano-silicon fertilizer (NC-NS) can ameliorate the adverse effect of salinity stress on wheat plants were evaluated in this study. The results showed that NC, NS, and NC-NS application significantly increased the function of enzymatic and non-enzymatic antioxidant systems, as well as the molecules with osmotic adjustment potentials, leading to the protection of cells against salinity-induced stress.
Review
Agronomy
Daniel P. Rasse, Simon Weldon, Erik J. Joner, Stephen Joseph, Claudia Kammann, Xiaoyu Liu, Adam O'Toole, Genxing Pan, N. Pelin Kocaturk-Schumacher
Summary: This review examines the mechanisms of biochar-based fertilizers on enhanced N uptake by plants and discusses the potential for further improvement. Current biochar products lack the sorption capacity needed for slow-release of high enough N concentration, indicating the need for further research and development.
Article
Polymer Science
Muhammad Mujtaba, Bahar Akyuz Yilmaz, Demet Cansaran-Duman, Lalehan Akyuz, Sevcan Yangin, Murat Kaya, Talip Ceter, Khalid Mahmood Khawar
Summary: The study successfully extracted sporopollenin and loaded oxaliplatin into it for controlled drug release, demonstrating a slow release effect. Real-time cell analysis and gene expression detection confirmed that sporopollenin-mediated oxaliplatin controlled release promotes apoptosis without causing negative effects on nearby healthy cells.
Article
Plant Sciences
Muhammet Cagri Oguz, Muhammad Mujtaba, Canan Yuksel Ozmen, Umut Kibar, Ahmet Metin Kumlay, Ali Ergul
Summary: In this study, comparative analysis was conducted to identify the role of genes bZIP60 and bZIP28 in ER stress response in plant root and leaf tissues. The study found that bZIP60 has a more active role in stress pathways and is associated with drought tolerance.
ACTA PHYSIOLOGIAE PLANTARUM
(2022)
Article
Plant Sciences
Ali Shahzad, Hameed Gul, Muhammad Ahsan, Depeng Wang, Shah Fahad
Summary: A shortage of water severely limits maize plant development, leading to reduced maize production. This study identified potential drought-tolerant maize germplasm using a two-step screening approach. It was found that certain inbred lines performed better than others under drought stress conditions at both the seedling and maturity stages. Traits related to root weight and density showed high heritability at the seedling stage, while traits such as grain yield per plant and leaf area exhibited higher genetic advance at the maturity stage. Selection based on these traits can help identify better germplasms under drought conditions and promote yield stability. These findings have implications for future maize breeding programs.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Review
Plant Sciences
Shah Saud, Depeng Wang, Shah Fahad
Summary: Based on an analysis of the current situation of nitrogen fertiliser application, it is suggested that improving the nitrogen utilisation efficiency of crops is an important means of promoting the sustainable development of agriculture and realising the zero increase in chemical fertiliser application. This can be achieved through the release of biological nitrification inhibitors (BNIs), which significantly improve crop yield, increase nitrogen utilisation rate, and reduce greenhouse gas emissions.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Sevil Saglam Yilmaz, Khalid Mahmood Khawar, Cemalettin Yasar Ciftci
Summary: The study investigates the use of Agrobacterium-based gene transformation to develop insect-resistant common bean varieties against seed beetles. The results showed successful generation of transgenic plants with resistance to legume seed insects. This research has important implications for producing better transgenic common bean germplasm and promoting sustainable agriculture with reduced environmental pollutions.
MOLECULAR BIOLOGY REPORTS
(2022)
Article
Multidisciplinary Sciences
Muhammad Adnan, Shah Fahad, Muhammad Hamzah Saleem, Baber Ali, Maria Mussart, Rafi Ullah, Jr. Amanullah, Muhammad Arif, Manzoor Ahmad, Wajid Ali Shah, Muhammad Romman, Fazli Wahid, Depeng Wang, Shah Saud, Ke Liu, Matthew Tom Harrison, Chao Wu, Subhan Danish, Rahul Datta, Crina Carmen Muresan, Romina Alina Marc
Summary: Phosphorus (P) deficiency is a major obstacle in sustainable crop production, especially in calcareous soils. The use of phosphate solubilizing bacteria (PSB) as bio-fertilizers can improve P availability in soil, and the application of organic amendments with PSB can further enhance the management of immobilized nutrients in calcareous soils.
SCIENTIFIC REPORTS
(2022)
Article
Agronomy
Neeshu Joshi, Sunita T. Pandey, V. Pratap Singh, Dinesh Jinger, Shourabh Joshi, Venkatesh Paramesh, Manoj Parihar, Rajesh Singhal, Talha Javed, Shah Saud, Shah Hassan, Depeng Wang, Chao Wu, Shah Fahad
Summary: By intercropping Brahmi with direct-seeded rice, weed management can be improved, pesticide usage can be reduced, and profitability can be increased.
INTERNATIONAL JOURNAL OF PLANT PRODUCTION
(2023)
Review
Green & Sustainable Science & Technology
Muhammad Mujtaba, Leonardo Fernandes Fraceto, Mahyar Fazeli, Sritama Mukherjee, Susilaine Maira Savassa, Gerson Araujo de Medeiros, Anderson do Espirito Santo Pereira, Sandro Donnini Mancini, Juha Lipponen, Francisco Vilaplana
Summary: In response to the global warming crisis caused by uncontrolled greenhouse gas production, industries are striving to reduce their dependence on petrochemicals and petroleum-based industrial components and replace them with biobased, sustainable, and environmentally friendly alternatives. Agricultural waste, particularly lignocellulosic biomass, provides a significant resource for the development of various bio-products. Recent advancements in integrated biorefineries have improved the utilization of waste lignocellulose components to produce biofuels, platform chemicals, resins, bioplastics, additives, and other biobased materials for diverse applications.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Plant Sciences
Tayyaba Naz, Muhammad Mazhar Iqbal, Shah Fahad, Javaid Akhtar, Muhammad Saqib, Saud Alamri, Manzer H. Siddiqui, Shah Saud, Jabar Zaman Khan Khattak, Shamsher Ali, Shah Hassan, Taufiq Nawaz, Hafiz Mohkum Hammad, Jan Banout, Chao Wu, Depeng Wang, Rahul Datta, Subhan Danish, Wajid Nasim
Summary: Salinity is a major environmental constraint in arid and semi-arid regions, depleting soil fertility and reducing uptake of micronutrients. Wheat, being a staple for a large population, is often low in important minerals like iron and zinc. Limited research exists on fortifying wheat with iron and zinc under saline conditions. This study aimed to assess the responses of selected wheat cultivars to soil and foliar application of iron and zinc under salt stress. Results showed that salt stress significantly deteriorated plant growth and yield, but application of iron and zinc increased wheat plant growth under salt stress. Foliar application was more efficient than soil application, and the combined application gave the highest yield and micronutrient accumulation in shoot and grains. This highlights the effectiveness of combined soil and foliar application in ameliorating micronutrient deficiency in crops grown in salt-affected soils.
JOURNAL OF PLANT GROWTH REGULATION
(2023)
Review
Engineering, Biomedical
Muhammad Mujtaba, Arvind Negi, Alistair W. T. King, Mina Zare, Johana Kuncova-Kallio
Summary: With the development of novel drugs and the discovery of new targets, there is an increased need for novel drug carriers. Nanocellulose has great potential to become a novel drug carrier thanks to its biocompatibility, low toxicity, tunable chemical structure, and sustainability. This review focuses on the modification of nanocellulose to enhance its capability as a drug delivery agent and pinpoints the pitfalls for the registration of such novel sustainable material.
CURRENT OPINION IN BIOMEDICAL ENGINEERING
(2023)
Article
Chemistry, Applied
Muhammad Mujtaba, Qasid Ali, Bahar Akyuz Yilmaz, Mehmet Seckin Kurubas, Hayri Ustun, Mustafa Erkan, Murat Kaya, Mehmet Cicek, Ebru Toksoy Oner
Summary: In this study, biobased composite coatings composed of chitosan, mucilage, and levan were applied on sweet cherry fruits and tested for postharvest parameters in both market and cold storage conditions. The results showed that the shelf life of sweet cherries can be extended until the 30th day while maintaining important post-harvest properties. The cost-effectiveness of the polymers used indicates the feasibility of extending the shelf-life of sweet cherries on a larger scale.
Article
Meteorology & Atmospheric Sciences
Muhammet Ali Pekin, Nurdan Sahin Demirbag, Khalid Mahmood Khawar, Halit Apaydin
Summary: This study uses an Artificial Neural Network model to predict the yield of alfalfa under different climate change scenarios. The results show that alfalfa can resist climate change and its yield tends to increase or decrease in regions with corresponding changes in precipitation. The highest yield increase is predicted in Artvin (6%) in Eastern Anatolia and the maximum yield decrease is predicted in Siirt (9%) in Southeastern Anatolia. This research provides a creative approach for estimating alfalfa yield.
Article
Environmental Sciences
Muhammad Aasim, Seyid Amjad Ali, Senar Aydin, Allah Bakhsh, Canan Sogukpinar, Mehmet Karatas, Khalid Mahmood Khawar, Mehmet Emin Aydin
Summary: Water bodies are prone to heavy metal accumulation, posing a threat to the environment and human health, especially in underdeveloped nations. The use of aquatic plants, like Ceratophyllum demersum L., for phytoremediation has been widely recognized as an eco-friendly solution. The study shows that C. demersum can effectively remove cadmium from water, and artificial intelligence-based models accurately predict the plant's performance.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Horticulture
Qasid Ali, Mehmet Seckin Kurubas, Muhammad Mujtaba, Abdul Wahed Nazari, Adem Dogan, Murat Kaya, Ebru Toksoy Oner, Bahar Akyuz Yilmaz, Mustafa Erkan
Summary: This study investigated the effects of bio-based coatings on the shelf life of cocktail tomatoes. The results showed that edible coating treatments minimized weight loss, ethylene emission, respiration rate, and unmarketable fruit, and slowed down the synthesis of lycopene. CS-MCLG-LVN coating treatment performed the best in terms of weight loss and unmarketable fruit. CS-MCLG-LVN and CS-MCLG treatments had the lowest ethylene emission and respiration rates. CS coating treatment exhibited the highest L* value and malic acid content, while CS-LVN had the highest total phenolic and total flavonoid contents. It can be concluded that CS-LVN, CS-MCLG, and CS-MCLG-LVN coatings maintained the postharvest quality of tomatoes for 30 days.
SCIENTIA HORTICULTURAE
(2024)
Article
Food Science & Technology
Guifeng Wang, Depeng Wang, Xiaoyan Zhou, Saud Shah, Lichen Wang, Mukhtar Ahmed, R. Z. Sayyed, Shah Fahad
Summary: Intercropping is widely used by farmers due to its ability to enhance crop productivity and economic returns. This study conducted a 2-year intercropping experiment in Northwest Shandong Province and proposed a green, ecological, and efficient intercropping mode suitable for the region. The results identified the optimal intercropping pattern, which resulted in significantly higher production efficiency compared to monoculture.
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
