Metastatic colorectal cancer: Advances in the folate-fluoropyrimidine chemotherapy backbone
出版年份 2021 全文链接
标题
Metastatic colorectal cancer: Advances in the folate-fluoropyrimidine chemotherapy backbone
作者
关键词
Metastatic colorectal cancer, 5-fluorouracil, Leucovorin, Chemotherapy
出版物
CANCER TREATMENT REVIEWS
Volume 98, Issue -, Pages 102218
出版商
Elsevier BV
发表日期
2021-05-04
DOI
10.1016/j.ctrv.2021.102218
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Folate pathway gene expression in metastatic colorectal cancer patients treated with arfolitixorin/5-FU-based chemotherapy.
- (2021) Roger Tell et al. JOURNAL OF CLINICAL ONCOLOGY
- Molecular characterization of a large unselected cohort of metastatic colorectal cancers in relation to primary tumor location, rare metastatic sites and prognosis
- (2020) Luís Nunes et al. ACTA ONCOLOGICA
- Incidence and risk markers of 5-fluorouracil and capecitabine cardiotoxicity in patients with colorectal cancer
- (2020) Anne Dyhl-Polk et al. ACTA ONCOLOGICA
- AGENT: An open-label phase III study of arfolitixorin versus leucovorin in modified FOLFOX-6 for first-line treatment of metastatic colorectal cancer.
- (2020) Heinz-Josef Lenz et al. JOURNAL OF CLINICAL ONCOLOGY
- TAS-102 with or without bevacizumab in patients with chemorefractory metastatic colorectal cancer: an investigator-initiated, open-label, randomised, phase 2 trial
- (2020) Per Pfeiffer et al. LANCET ONCOLOGY
- O-19 Feasibility of switching to S-1 upon other fluoropyrimidine-related cardiotoxicity during chemotherapy for solid tumors
- (2020) P. Osterlund et al. ANNALS OF ONCOLOGY
- 464P Pharmacokinetic analysis of NUC-3373 with and without leucovorin in patients with previously treated metastatic colorectal cancer (NuTide:302 study)
- (2020) J. Graham et al. ANNALS OF ONCOLOGY
- Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer
- (2020) Thierry André et al. NEW ENGLAND JOURNAL OF MEDICINE
- NuTide:302: A phase Ib study to assess the safety, pharmacokinetics and clinical activity of the ProTide NUC-3373 when combined with standard agents used in colorectal cancer.
- (2019) T.R. Jeffry Evans et al. JOURNAL OF CLINICAL ONCOLOGY
- First-in-human phase I study of infusional and bolus schedules of Deflexifol, a novel 5-fluorouracil and leucovorin formulation, after failure of standard treatment
- (2019) Philip R. Clingan et al. Asia-Pacific Journal of Clinical Oncology
- Consequences of a high incidence of microsatellite instability and BRAF‐ mutated tumors: A population‐based cohort of metastatic colorectal cancer patients
- (2019) Kristine Ø. Aasebø et al. Cancer Medicine
- DPYD and Fluorouracil-Based Chemotherapy: Mini Review and Case Report
- (2019) Theodore J. Wigle et al. Pharmaceutics
- Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial
- (2019) Cathy Eng et al. LANCET ONCOLOGY
- Reduced-dose combination chemotherapy (S-1 plus oxaliplatin) versus full-dose monotherapy (S-1) in older vulnerable patients with metastatic colorectal cancer (NORDIC9): a randomised, open-label phase 2 trial
- (2019) Stine Braendegaard Winther et al. Lancet Gastroenterology & Hepatology
- Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer
- (2019) Scott Kopetz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Primary Tumor Sidedness Predicts Bevacizumab Benefit in Metastatic Colorectal Cancer Patients
- (2019) Xia-Hong You et al. Frontiers in Oncology
- 527PDTrastuzumab and tucatinib for the treatment of HER2 amplified metastatic colorectal cancer (mCRC): Initial results from the MOUNTAINEER trial
- (2019) J H Strickler et al. ANNALS OF ONCOLOGY
- Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair–Deficient/Microsatellite Instability–High Metastatic Colorectal Cancer
- (2018) Michael J. Overman et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study
- (2018) John D. Hainsworth et al. JOURNAL OF CLINICAL ONCOLOGY
- Modified XELIRI (capecitabine plus irinotecan) versus FOLFIRI (leucovorin, fluorouracil, and irinotecan), both either with or without bevacizumab, as second-line therapy for metastatic colorectal cancer (AXEPT): a multicentre, open-label, randomised, non-inferiority, phase 3 trial
- (2018) Rui-Hua Xu et al. LANCET ONCOLOGY
- Association Between Serum Folate Level and Toxicity of Capecitabine During Treatment for Colorectal Cancer
- (2018) Stephen L. Chan et al. ONCOLOGIST
- Relationship Between Thymidine Kinase 1 Expression and Trifluridine/Tipiracil Therapy in Refractory Metastatic Colorectal Cancer: A Pooled Analysis of 2 Randomized Clinical Trials
- (2018) Takayuki Yoshino et al. Clinical Colorectal Cancer
- Folate gene prediction of treatment response to 5-FU and leucovorin in advanced colorectal cancer.
- (2018) Bengt Gustavsson et al. JOURNAL OF CLINICAL ONCOLOGY
- A prospective phase II study of raltitrexed combined with S-1 as salvage treatment for patients with metastatic colorectal cancer after failure of standard chemotherapy.
- (2018) Mingzhu Huang et al. JOURNAL OF CLINICAL ONCOLOGY
- 569PISO-CC-005; A phase I/II study of arfolitixorin (MTHF) in combination with 5-FU, irinotecan, and oxaliplatin ± bevacizumab in patients with metastasizing colorectal cancer
- (2018) G U Carlsson et al. ANNALS OF ONCOLOGY
- LBA18_PRDurable clinical benefit with nivolumab (NIVO) plus low-dose ipilimumab (IPI) as first-line therapy in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC)
- (2018) H-J J Lenz et al. ANNALS OF ONCOLOGY
- Efficacy of bevacizumab in first-line treatment of metastatic colorectal cancer: A systematic review and meta-analysis
- (2018) Alexander Baraniskin et al. EUROPEAN JOURNAL OF CANCER
- Case series of patients treated with the oral fluoropyrimidine S-1 after capecitabine-induced coronary artery vasospasm
- (2017) Johannes J.M. Kwakman et al. EUROPEAN JOURNAL OF CANCER
- Recent Advances in Targeting the EGFR Signaling Pathway for the Treatment of Metastatic Colorectal Cancer
- (2017) Yuji Miyamoto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Prevention of 5-fluorouracil-induced early severe toxicity by pre-therapeutic dihydropyrimidine dehydrogenase deficiency screening: Assessment of a multiparametric approach
- (2017) Michele Boisdron-Celle et al. SEMINARS IN ONCOLOGY
- ESMO consensus guidelines for the management of patients with metastatic colorectal cancer
- (2016) E. Van Cutsem et al. ANNALS OF ONCOLOGY
- Folates as adjuvants to anticancer agents: Chemical rationale and mechanism of action
- (2016) Peter V. Danenberg et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- ExtendedRASGene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti–Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015
- (2016) Carmen J. Allegra et al. JOURNAL OF CLINICAL ONCOLOGY
- Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial
- (2016) Andrea Sartore-Bianchi et al. LANCET ONCOLOGY
- Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation
- (2016) D. S. Hong et al. Cancer Discovery
- Beating the odds: efficacy and toxicity of dihydropyrimidine dehydrogenase-driven adaptive dosing of 5-FU in patients with digestive cancer
- (2015) Manon Launay et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- TAS-102, a novel antitumor agent: A review of the mechanism of action
- (2015) Heinz-Josef Lenz et al. CANCER TREATMENT REVIEWS
- A Review of the Evolution of Systemic Chemotherapy in the Management of Colorectal Cancer
- (2015) Bengt Gustavsson et al. Clinical Colorectal Cancer
- Predictive role of BRAF mutations in patients with advanced colorectal cancer receiving cetuximab and panitumumab: A meta-analysis
- (2015) Filippo Pietrantonio et al. EUROPEAN JOURNAL OF CANCER
- Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer
- (2015) Scott Kopetz et al. JOURNAL OF CLINICAL ONCOLOGY
- Unknown
- (2015) Elisabeth Odin et al. MOLECULAR MEDICINE
- The consensus molecular subtypes of colorectal cancer
- (2015) Justin Guinney et al. NATURE MEDICINE
- Randomized Trial of TAS-102 for Refractory Metastatic Colorectal Cancer
- (2015) Robert J. Mayer et al. NEW ENGLAND JOURNAL OF MEDICINE
- High BRAF Mutation Frequency and Marked Survival Differences in Subgroups According to KRAS/BRAF Mutation Status and Tumor Tissue Availability in a Prospective Population-Based Metastatic Colorectal Cancer Cohort
- (2015) Halfdan Sorbye et al. PLoS One
- The predictive value ofKRAS, NRAS, BRAF, PIK3CAand PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis
- (2014) Christina Therkildsen et al. ACTA ONCOLOGICA
- Final results from PRIME: randomized phase III study of panitumumab with FOLFOX4 for first-line treatment of metastatic colorectal cancer
- (2014) J. Y. Douillard et al. ANNALS OF ONCOLOGY
- A pharmacokinetic and pharmacodynamic investigation of Modufolin® compared to Isovorin® after single dose intravenous administration to patients with colon cancer: a randomized study
- (2014) Yvonne Wettergren et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Folate levels measured by LC–MS/MS in patients with colorectal cancer treated with different leucovorin dosages
- (2014) Helena Taflin et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies
- (2014) S. Venderbosch et al. CLINICAL CANCER RESEARCH
- Standing the test of time: targeting thymidylate biosynthesis in cancer therapy
- (2014) Peter M. Wilson et al. Nature Reviews Clinical Oncology
- Final results of Australasian Gastrointestinal Trials Group ARCTIC study: an audit of raltitrexed for patients with cardiac toxicity induced by fluoropyrimidines
- (2013) D. Ransom et al. ANNALS OF ONCOLOGY
- Targeting thymidylate synthase in colorectal cancer: critical re-evaluation and emerging therapeutic role of raltitrexed
- (2013) Antonio Avallone et al. Expert Opinion On Drug Safety
- Effect of Halogen Substitutions on dUMP to Stability of Thymidylate Synthase/dUMP/mTHF Ternary Complex Using Molecular Dynamics Simulation
- (2013) Nopporn Kaiyawet et al. Journal of Chemical Information and Modeling
- Palliative first-line therapy with weekly high-dose 5-fluorouracil and sodium folinic acid as a 24-hour infusion (AIO regimen) combined with weekly irinotecan in patients with metastatic adenocarcinoma of the stomach or esophagogastric junction followed by secondary metastatic resection after downsizing
- (2013) Kathrin Koucky et al. MEDICAL SCIENCE MONITOR
- Alternative Treatment Options in Colorectal Cancer Patients With 5–Fluorouracil- or Capecitabine-Induced Cardiotoxicity
- (2012) Guido Deboever et al. Clinical Colorectal Cancer
- S-1 plus oxaliplatin versus capecitabine plus oxaliplatin for first-line treatment of patients with metastatic colorectal cancer: a randomised, non-inferiority phase 3 trial
- (2012) Yong Sang Hong et al. LANCET ONCOLOGY
- EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF -Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib
- (2012) Ryan B. Corcoran et al. Cancer Discovery
- Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation Status
- (2011) Eric Van Cutsem et al. JOURNAL OF CLINICAL ONCOLOGY
- Is Levoleucovorin an Alternative to Racemic Leucovorin? A Literature Review
- (2009) Philip A. Kovoor et al. Clinical Colorectal Cancer
- Capecitabine: have we got the dose right?
- (2008) Rachel Midgley et al. Nature clinical practice. Oncology
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