Acute exercise stress promotes Ref1/Nrf2 signalling and increases mitochondrial antioxidant activity in skeletal muscle

A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions

(2015) S. Thakur et al.   CELL BIOCHEMISTRY AND FUNCTION

Treadmill exercise activates Nrf2 antioxidant system to protect the nigrostriatal dopaminergic neurons from MPP+ toxicity

(2015) Yi-Hsien Tsou et al.   EXPERIMENTAL NEUROLOGY

The activation of the Nrf2/ARE pathway in HepG2 hepatoma cells by phytochemicals and subsequent modulation of phase II and antioxidant enzyme expression

(2015) Violetta Krajka-Kuźniak et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Activation of the Nrf2 defense pathway contributes to neuroprotective effects of phloretin on oxidative stress injury after cerebral ischemia/reperfusion in rats

(2015) Yu Liu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Acute Exercise Induced Mitochondrial H2O2Production in Mouse Skeletal Muscle: Association with p66Shcand FOXO3a Signaling and Antioxidant Enzymes

(2015) Ping Wang et al.   Oxidative Medicine and Cellular Longevity

Exercise-Induced Skeletal Muscle Remodeling and Metabolic Adaptation: Redox Signaling and Role of Autophagy

(2014) Elisabetta Ferraro et al.   ANTIOXIDANTS & REDOX SIGNALING

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

(2014) Ke Ding et al.   FREE RADICAL BIOLOGY AND MEDICINE

Apurinic/Apyrimidinic Endonuclease/Redox Factor-1 (APE1/Ref-1) Redox Function Negatively Regulates NRF2

(2014) Melissa L. Fishel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant Supplement Inhibits Skeletal Muscle Constitutive Autophagy rather than Fasting-Induced Autophagy in Mice

(2014) Zhengtang Qi et al.   Oxidative Medicine and Cellular Longevity

mTOR signaling response to resistance exercise is altered by chronic resistance training and detraining in skeletal muscle

(2013) Riki Ogasawara et al.   JOURNAL OF APPLIED PHYSIOLOGY

Specific Inhibition of the Redox Activity of Ape1/Ref-1 by E3330 Blocks Tnf-Α-Induced Activation of Il-8 Production in Liver Cancer Cell Lines

(2013) Laura Cesaratto et al.   PLoS One

Redox homeostasis: the linchpin in stem cell self-renewal and differentiation

(2013) Kui Wang et al.   Cell Death & Disease

Glutathione synthesis

(2012) Shelly C. Lu   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Disruption of Nrf2/ARE signaling impairs antioxidant mechanisms and promotes cell degradation pathways in aged skeletal muscle

(2012) Corey J. Miller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium

(2011) Vasanthi R. Muthusamy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Import, Maturation, and Function of SOD1 and Its Copper Chaperone CCS in the Mitochondrial Intermembrane Space

(2010) Hibiki Kawamata et al.   ANTIOXIDANTS & REDOX SIGNALING

Excitation-transcription coupling in skeletal muscle: the molecular pathways of exercise

(2010) Kristian Gundersen   BIOLOGICAL REVIEWS

Dysfunctional Nrf2–Keap1 redox signaling in skeletal muscle of the sedentary old

(2010) Adeel Safdar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Exercise training attenuates oxidative stress and decreases p53 protein content in skeletal muscle of type 2 diabetic Goto-Kakizaki rats

(2010) Zhengtang Qi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Manganese superoxide dismutase vs. p53: Regulation of mitochondrial ROS

(2010) Aaron K. Holley et al.   MITOCHONDRION

Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility

(2009) Juan Lu et al.   FASEB JOURNAL

Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice

(2009) N. M. Reddy et al.   JOURNAL OF IMMUNOLOGY

Isolation of mitochondria for biogenetical studies: An update

(2009) Erika Fernández-Vizarra et al.   MITOCHONDRION

Nrf2 Signaling, a Mechanism for Cellular Stress Resistance in Long-Lived Mice

(2009) S. F. Leiser et al.   MOLECULAR AND CELLULAR BIOLOGY

APE/Ref-1 makes fine-tuning of CD40-induced B cell proliferation

(2008) Sonia Merluzzi et al.   MOLECULAR IMMUNOLOGY

Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults

(2007) W OSBURN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH