The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation

Longdan Xiegan Decoction alleviates experimental autoimmune uveitis in rats by inhibiting Notch signaling pathway activation and Th17 cell differentiation

(2021) Xuewei Yin et al.   BIOMEDICINE & PHARMACOTHERAPY

miR-146a rs2431697 identifies myeloproliferative neoplasm patients with higher secondary myelofibrosis progression risk

(2020) F. Ferrer-Marín et al.   LEUKEMIA

Glycogen Synthase Kinase-3 and phospholipase C-beta signalling: Roles and possible interactions in myelodysplastic syndromes and acute myeloid leukemia

(2020) Stefano Ratti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Oral Arsenic-Containing Qinghuang Powder (青黄散): A Potential Drug for Myelodysplastic Syndromes

(2020) Jing Ming et al.   Chinese Journal of Integrative Medicine

Role of DNA Damage Response in Suppressing Malignant Progression of Chronic Myeloid Leukemia and Polycythemia Vera: Impact of Different Oncogenes

(2020) Jan Stetka et al.   Cancers

Novel agents for the treatment of polycythemia vera: an insight into preclinical research and early phase clinical trials

(2020) Leslie Padrnos et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation

(2020) Meiyu Jin et al.   Oxidative Medicine and Cellular Longevity

The Role of Inflammation and Inflammasome in Myeloproliferative Disease

(2020) Lucia Longhitano et al.   Journal of Clinical Medicine

Synergic Crosstalk between Inflammation, Oxidative Stress, and Genomic Alterations in BCR–ABL-Negative Myeloproliferative Neoplasm

(2020) Alessandro Allegra et al.   Antioxidants

Elucidation of the molecular mechanism of Sanguisorba Officinalis L. against leukopenia based on network pharmacology

(2020) Long Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Novel therapeutics in myeloproliferative neoplasms

(2020) Sangeetha Venugopal et al.   Journal of Hematology & Oncology

Saikosaponin d ameliorates pancreatic fibrosis by inhibiting autophagy of pancreatic stellate cells via PI3K/Akt/mTOR pathway

(2019) Li-Hua Cui et al.   CHEMICO-BIOLOGICAL INTERACTIONS

SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules

(2019) Antoine Daina et al.   NUCLEIC ACIDS RESEARCH

Saikosaponin-d Suppresses COX2 Through p-STAT3/C/EBPβ Signaling Pathway in Liver Cancer: A Novel Mechanism of Action

(2019) Mudan Ren et al.   Frontiers in Pharmacology

Vascular malformations syndromes

(2019) Antonio Martinez-Lopez et al.   CURRENT OPINION IN PEDIATRICS

Identification of new antiviral agents against Kaposi’s sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation

(2019) Jungang Chen et al.   PLoS Pathogens

Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway

(2019) Ruijie Sun et al.   Cancer Medicine

Classification and Personalized Prognosis in Myeloproliferative Neoplasms

(2018) Jacob Grinfeld et al.   NEW ENGLAND JOURNAL OF MEDICINE

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

ETCM: an encyclopaedia of traditional Chinese medicine

(2018) Hai-Yu Xu et al.   NUCLEIC ACIDS RESEARCH

A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm

(2017) D. A. Casolari et al.   Scientific Reports

Saikosaponin-a Attenuates Oxidized LDL Uptake and Prompts Cholesterol Efflux in THP-1 Cells

(2016) Dan He et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

The ChEMBL database in 2017

(2016) Anna Gaulton et al.   NUCLEIC ACIDS RESEARCH

Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery ofJAK2 V617F

(2015) Brady L. Stein et al.   JOURNAL OF CLINICAL ONCOLOGY

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Anti-Apoptotic Pathways in Bone Marrow and Megakaryocytes in Myeloproliferative Neoplasia

(2013) Suzanne M. Koopmans et al.   PATHOBIOLOGY

STAT proteins – Key regulators of anti-viral responses, inflammation, and tumorigenesis in the liver

(2012) Bin Gao et al.   JOURNAL OF HEPATOLOGY

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism

(2011) E. Nitta et al.   BLOOD

Increased phosphatidylserine exposure on the erythrocyte membrane in patients with polycythaemia vera

(2010) Hiroshi Fujita et al.   BRITISH JOURNAL OF HAEMATOLOGY

PubChem BioAssays as a data source for predictive models

(2009) Bin Chen et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING