Article
Microbiology
Razieh Kebriaei, Katherine L. Lev, Rahi M. Shah, Kyle C. Stamper, Dana J. Holger, Taylor Morrisette, Ashlan J. Kunz Coyne, Susan M. Lehman, Michael J. Rybak
Summary: Bacterial biofilms are difficult to eradicate and can complicate infections. Phage+antibiotic combinations (PAC) may be more effective on biofilms than single agents. Our study demonstrated the effectiveness of phage Sb-1 on MRSA biofilms and suggested PAC regimens as adjuncts to antibiotics.
MICROBIOLOGY SPECTRUM
(2022)
Article
Biotechnology & Applied Microbiology
Aparna Nair, Renuka Vyawahare, Krishna Khairnar
Summary: The novel bacteriophage En5822 isolated from the environment shows high lytic activity, specificity, and biofilm reduction capability against Enterobacter cloacae. Its genomic and physical attributes make it a potential alternative antimicrobial for treating drug-resistant infections.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Review
Microbiology
Cheng Chang, Xinbo Yu, Wennan Guo, Chaoyi Guo, Xiaokui Guo, Qingtian Li, Yongzhang Zhu
Summary: Biofilms are complex microbial microcolonies that are resistant to antibiotics and can adhere to various surfaces. Using bacteriophages and their components for biofilm removal shows promise, but there are still challenges to overcome.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Microbiology
Michelle Marie Esposito, Sara Turku
Summary: Biofilms are large aggregates of various species of bacteria or other microorganisms tightly attached to surfaces through an intricate extracellular matrix. These complex microbial communities present significant challenges in the food processing industry due to the potential for contamination and the resistance of biofilm growth to traditional antimicrobials. Natural methods, such as bacteriocins, bacteriophages, fungi, phytochemicals, and plant extracts, have been explored as potential means to target foodborne biofilms.
Article
Virology
Sanna Sillankorva, Liliana Pires, Lorenzo M. Pastrana, Manuel Banobre-Lopez
Summary: The prevalence of drug-resistant bacteria in chronic skin wounds and biofilm-related infections is a major concern. This study demonstrates the potential of using dissolving microneedles loaded with bacteriophages to effectively combat biofilm-related skin infections.
Article
Multidisciplinary Sciences
Fedor Zurabov, Egor Glazunov, Tatiana Kochetova, Viktoria Uskevich, Valentina Popova
Summary: Klebsiella pneumoniae is a dangerous bacterium associated with various infections, especially in medical facilities. The emergence of drug-resistant and highly virulent strains, as well as the ability to form biofilms, complicates treatment and renders antibiotics ineffective. This study found that using a specific cocktail of bacteriophages can effectively disrupt Klebsiella pneumoniae biofilms.
SCIENTIFIC REPORTS
(2023)
Article
Microbiology
Esther Shmidov, Ilana Lebenthal-Loinger, Shira Roth, Sarit Karako-Lampert, Itzhak Zander, Sivan Shoshani, Amos Danielli, Ehud Banin
Summary: The functions of bacterial TA systems are still disputed and poorly understood. This study sheds light on potential functions of bacterial TA systems. The novel type II TA system PrrT/A in Pseudomonas aeruginosa is found to regulate biofilm formation, motility, prophage induction, bacteriophage production, and aminoglycoside resistance, providing new insights into the diverse roles and impacts of TA systems in bacteria.
MICROBIOLOGY SPECTRUM
(2022)
Article
Infectious Diseases
Jean Pierre Gonzalez-Gomez, Berenice Gonzalez-Torres, Pedro Javier Guerrero-Medina, Osvaldo Lopez-Cuevas, Cristobal Chaidez, Maria Guadalupe Avila-Novoa, Melesio Gutierrez-Lomeli
Summary: Biofilm formation by E. coli in meat processing plants poses a significant threat, and bacteriophages are a promising alternative for biofilm control. In this study, three bacteriophages with lytic activity against biofilm-forming E. coli strains were isolated from meat samples and showed effectiveness in reducing biofilms. However, the efficacy of bacteriophages varied based on the E. coli strains, phage concentration, and biofilm maturity. Expanding the library of phages targeting strains from production environments is necessary for improved biofilm control.
Article
Engineering, Environmental
Mary Luz Barrios-Hernandez, Carolina Bettinelli, Karen Mora-Cabrera, Maria-Clara Vanegas-Camero, Hector Garcia, Jack van de Vossenberg, Daniel Prats, Damir Brdjanovic, Mark C. M. van Loosdrecht, Christine M. Hooijmans
Summary: This study focused on the removal of bacterial and viral surrogates by aerobic granular sludge systems, showing a reduction in both Escherichia coli and MS2 bacteriophages during different operational phases. Predation during aeration was the main mechanism for removal, with different impacts on each surrogate organism.
Review
Microbiology
Faizan Ahmed Sadiq, Mads Frederik Hansen, Mette Burmolle, Marc Heyndrickx, Steve Flint, Wenwei Lu, Wei Chen, Hao Zhang
Summary: Biofilms, complex surface-adhered microbial communities, consist of microorganisms from different kingdoms of life and play a significant role in ecological interactions. The study of interactions between species from different kingdoms in biofilms has advanced our knowledge of microbial ecology and its applications in medical microbiology, biotechnology, and understanding microbial life in nature.
FEMS MICROBIOLOGY REVIEWS
(2022)
Article
Food Science & Technology
Divya Jaroni, Pushpinder Kaur Litt, Punya Bule, Kaylee Rumbaugh
Summary: This study evaluated the effects of previously isolated and characterized bacteriophages on biofilms formed by Shiga-toxigenic Escherichia coli (STEC). Results showed that 77% of the phages could disrupt STEC biofilms in vitro. Serotype-specific phage treatments significantly reduced pathogen population within the biofilms, while a 21-phage cocktail showed better efficacy on different food-contact surfaces.
Article
Microbiology
Carly M. Davis, Jaclyn G. McCutcheon, Jonathan J. Dennis
Summary: This study investigates the morphological changes induced by sub-MIC levels of the antibiotic aztreonam lysine (AzLys) on Pseudomonas aeruginosa, and the synergistic inhibitory effects of bacteriophages combined with antibiotics on bacteria. The results show that sub-inhibitory AzLys-induced filamentation of P. aeruginosa cells leads to a decrease in bacterial motility, while the combination of phage and AzLys significantly reduces biofilm growth.
Article
Microbiology
L. Blasco, I Bleriot, M. Gonzalez de Aledo, L. Fernandez-Garcia, O. Pacios, H. Oliveira, M. Lopez, C. Ortiz-Cartagena, F. Fernandez-Cuenca, A. Pascual, L. Martinez-Martinez, J. Pachon, J. Azeredo, M. Tomas
Summary: The emergence of multidrug resistant bacteria has led to the need for alternatives to antibiotic therapy, and phage therapy has been identified as a potential solution. In this study, the adaptation process was used to develop a phage specifically targeting Acinetobacter baumannii. The adapted phage demonstrated an increased host range and expressed a depolymerase, which enhanced its antimicrobial activity. When combined with another phage, the phage cocktail showed strong antimicrobial and antibiofilm activity against A. baumannii strains.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2022)
Article
Chemistry, Applied
Bruna Webber, Emanuele S. Pottker, Natalie N. Rizzo, Adriana S. P. Nuncio, Caroline S. Peixoto, Enzo Mistura, Luciana R. dos Santos, Laura B. Rodrigues, Vladimir P. do Nascimento
Summary: This study evaluated the action of three bacteriophages in inhibiting the adhesion and removal of Salmonella Heidelberg biofilm. Results showed that individual or combined use of bacteriophages had significant effects on adhesion and biofilm removal of Salmonella Heidelberg. The synergistic combination of bacteriophages was found to be the most effective option, and the use of bacteriophage pool in surface conditioning was a feasible method for controlling Salmonella Heidelberg biofilms.
FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL
(2023)
Review
Biotechnology & Applied Microbiology
Fedrick C. Mgomi, Lei Yuan, Cao-Wei Chen, Yuan-Song Zhang, Zhen-Quan Yang
Summary: Mixed-species biofilms are common in food processing environments and are more difficult to control than single-species biofilms. Biofilms formed by foodborne pathogens can lead to serious human diseases. Researchers are looking for more effective methods to control mixed-species biofilms, and the use of bacteriophages in the food industry has shown significant growth as an alternative to conventional methods.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Review
Food Science & Technology
Gabriela Maia Danielski, Alberto Goncalves Evangelista, Fernando Bittencourt Luciano, Renata Ernlund Freitas de Macedo
Summary: Meat and meat products are susceptible to pathogenic or spoilage bacteria, causing economic losses and public health threats. Non-conventional microorganisms and biometabolites have potential for bio protection, improving the quality and safety of meat products.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Biotechnology & Applied Microbiology
Luiz F. Bianchini, Romeu C. P. da Silva Ramos, Nicoly S. de Oliveira, Rafaela C. de Paula, Rosimeire T. Rosa, Jarka Glassey, Edvaldo A. R. Rosa
Summary: The hybrid fixed bed-airlift reactor model showed superior hydrodynamic and rheological parameters, improved oxygenation process, and facilitated fungal biofilm formation, leading to enhanced biotransformation processes. High-performance liquid chromatography analyses confirmed the effectiveness of the model in drug biotransformation.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2021)
Article
Food Science & Technology
Jessica Audrey Feijo Correa, Joao Vitor Garcia dos Santos, Alberto Goncalves Evangelista, Anne Caroline Schoch Marques Pinto, Renata Ernlund Freitas de Macedo, Fernando Bittencourt Luciano
Summary: This study found that combinations of EOCs and PAs can have antimicrobial effects in food and significantly reduce the amount of EOC required. In experiments with sliced ham, it was discovered that CINN and HCA are the most effective combination for inhibiting the growth of foodborne pathogens.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Camila Demarco Maito, Antonio Diego Brandao Melo, Angela Cristina da Fonseca de Oliveira, Jansller Luiz Genova, Jair Rodini Engracia Filho, Renata Ernlund Freitas de Macedo, Kelly Mazutti Monteiro, Saulo Henrique Weber, Astrid Koppenol, Leandro Batista Costa
Summary: This study investigated the effect of combining calcium butyrate with tannin extract on the growth performance, incidence of diarrhea, intestinal histology, and immune-expression in piglets. The results showed that the combination of calcium butyrate and tannin extract significantly reduced the incidence of diarrhea and inflammatory processes in the duodenum of piglets. Therefore, this combination could be used as an alternative to reduce the use of antimicrobials in the diet of weaned piglets.
Review
Food Science & Technology
Alberto Goncalves Evangelista, Gabriela Maia Danielski, Jessica Audrey Feijo Correa, Caroline Maria de Andrade Cavalari, Isabelle Ramos Souza, Fernando Bittencourt Luciano, Renata Ernlund Freitas de Macedo
Summary: Carnobacterium bacteria have shown potential as probiotics and bioprotective agents, particularly in animal production and the food industry. However, research on human health applications is still in the early stages and there is a lack of in vivo studies, limiting its widespread use.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Agriculture, Dairy & Animal Science
Victor Erpen Broering, Orozimbo Furlan Junior, Nicoly Subtil de Oliveira, Ruediger Daniel Ollhoff, Igor Vivian de Almeida, Edvaldo Antonio Ribeiro Rosa
Summary: Feathers, as a by-product of the poultry meat industry, pose serious environmental and health risks, with large amounts being disposed of through burning or burying each year. However, due to their protein nature, feathers can be used as a source of energy by converting them into methane-rich biogas, known as biomethane. This review focuses on biotechnological aspects aimed at increasing the production of methane-rich biogas, covering topics such as feather quality, keratin hydrolysis, methane production, and ammonia stripping.
WORLDS POULTRY SCIENCE JOURNAL
(2023)
Article
Agriculture, Dairy & Animal Science
Bruno I. C. de Oliveira, Jose L. Martinez, Francinea A. F. de Souza, Saulo H. Weber, Edvaldo A. R. Rosa, Eduardo H. Birgel Jr, R. Daniel Ollhoff
Summary: The effects of using 5% Melaleuca alternifolia tea tree essential oil as an internal teat sealant to treat Murrah cows were evaluated. The results showed that the tea tree oil was effective in killing bacteria and compatible with the buffalo's mammary tissue. The study suggests that using tea tree oil under field conditions can protect the udder health of buffalo during the dry period.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2023)
Article
Agriculture, Dairy & Animal Science
Jansller Luiz Genova, Antonio Diego Brandao Melo, Paulo Evaristo Rupolo, Renata Ernlund Freitas de Macedo, Jair Rodini Engracia, Silvana Teixeira Carvalho, Luigi Faucitano, Leandro Batista Costa, Paulo Levi de Oliveira Carvalho
Summary: This study aimed to assess the effects of adding intestinal alkaline phosphatase to diets on piglets challenged with Escherichia coli. The results showed that feeding 30 mg IAP inhibited Enterobacteriaceae population and suggested a potential effect in mitigating intestinal injuries.
REVISTA BRASILEIRA DE ZOOTECNIA-BRAZILIAN JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Biology
Marcia Regina Beux, Suelen Avila, Monica Surek, Keliani Bordin, Jaqueline Leobet, Fabiana Barbieri, Sila Mary Rodrigues Ferreira, Edvaldo Antonio Ribeiro Rosa
Summary: This study analyzed the microbial community in the nest pots of Tetragonisca angustula bees and found various bacteria and yeast species. Bacillus was the dominant bacteria in honey and pollen, while Z. bailli was the dominant yeast in pollen and S. meliponinorum was the dominant yeast in honey.
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
(2022)
