Glucotoxicity-induced suppression of Cox6a2 expression provokes β-cell dysfunction via augmented ROS production

Establishment of a long-term stable β-cell line and its application to analyze the effect of Gcg expression on insulin secretion

(2021) Satsuki Miyazaki et al.   Scientific Reports

Nicotinamide nucleotide transhydrogenase (NNT) regulates mitochondrial ROS and endothelial dysfunction in response to angiotensin II

(2020) K.N. Shashanka Rao et al.   Redox Biology

CLICK: one-step generation of conditional knockout mice

(2018) Yoshiki Miyasaka et al.   BMC GENOMICS

ChIP‐Atlas: a data‐mining suite powered by full integration of public ChIP‐seq data

(2018) Shinya Oki et al.   EMBO REPORTS

Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells

(2016) Melissa F. Brereton et al.   Nature Communications

Short-term selective alleviation of glucotoxicity and lipotoxicity ameliorates the suppressed expression of key β-cell factors under diabetic conditions

(2015) Naoki Shimo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Preserving Mafa Expression in Diabetic Islet β-Cells Improves Glycemic Controlin Vivo

(2015) Taka-aki Matsuoka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

(2014) Yan Hang et al.   DIABETES

A spontaneous mutation in the nicotinamide nucleotide transhydrogenase gene of C57BL/6J mice results in mitochondrial redox abnormalities

(2013) Juliana A. Ronchi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance

(2013) Roel Quintens et al.   PLoS One

TAp73 depletion accelerates aging through metabolic dysregulation

(2012) A. Rufini et al.   GENES & DEVELOPMENT

Regulation of MafA Expression in Pancreatic  -Cells in db/db Mice With Diabetes

(2010) T.-a. Matsuoka et al.   DIABETES