Drug delivery strategies to control macrophages for tissue repair and regeneration

Spatially localized recruitment of anti-inflammatory monocytes by SDF-1α-releasing hydrogels enhances microvascular network remodeling

(2016) J.R. Krieger et al.   BIOMATERIALS

Recruitment of mesenchymal stem cells and macrophages by dual release of stromal cell-derived factor-1 and a macrophage recruitment agent enhances wound closure

(2016) Yang-Hee Kim et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Localized delivery of dexamethasone-21-phosphate via microdialysis implants in rat induces M(GC) macrophage polarization and alters CCL2 concentrations

(2015) Geoffrey D. Keeler et al.   Acta Biomaterialia

Controlled release of cytokines using silk-biomaterials for macrophage polarization

(2015) Andrew R.D. Reeves et al.   BIOMATERIALS

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds

(2015) Kara L. Spiller et al.   BIOMATERIALS

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

(2015) Johanna A. Knipper et al.   IMMUNITY

Relative Expression of Proinflammatory and Antiinflammatory Genes Reveals Differences between Healing and Nonhealing Human Chronic Diabetic Foot Ulcers

(2015) Sina Nassiri et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Macrophage responses to implants: prospects for personalized medicine

(2015) Julia Kzhyshkowska et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

(2015) Omid Veiseh et al.   NATURE MATERIALS

Multinucleated Giant Cells Are Specialized for Complement-Mediated Phagocytosis and Large Target Destruction

(2015) Ronny Milde et al.   Cell Reports

Improved Angiogenesis in Response to Localized Delivery of Macrophage-Recruiting Molecules

(2015) Chih-Wei Hsu et al.   PLoS One

The Development of Macrophage-Mediated Cell Therapy to Improve Skeletal Muscle Function after Injury

(2015) Viktoriya Rybalko et al.   PLoS One

Fracture Healing via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Early Endochondral Ossification

(2014) Liza J. Raggatt et al.   AMERICAN JOURNAL OF PATHOLOGY

Macrophages Modulate Engineered Human Tissues for Enhanced Vascularization and Healing

(2014) Kara L. Spiller et al.   ANNALS OF BIOMEDICAL ENGINEERING

The role of macrophage phenotype in vascularization of tissue engineering scaffolds

(2014) Kara L. Spiller et al.   BIOMATERIALS

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Modulation of mouse macrophage polarizationin vitrousing IL-4 delivery by osmotic pumps

(2014) Jukka Pajarinen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Pro-Inflammatory Chemokine CCL2 (MCP-1) Promotes Healing in Diabetic Wounds by Restoring the Macrophage Response

(2014) Stephen Wood et al.   PLoS One

Wound Administration of M2-Polarized Macrophages Does Not Improve Murine Cutaneous Healing Responses

(2014) Nadine Jetten et al.   PLoS One

Enhancement of bone regeneration by dual release of a macrophage recruitment agent and platelet-rich plasma from gelatin hydrogels

(2013) Yang-Hee Kim et al.   BIOMATERIALS

Sustained Inflammasome Activity in Macrophages Impairs Wound Healing in Type 2 Diabetic Humans and Mice

(2013) R. E. Mirza et al.   DIABETES

Blocking Interleukin-1  Induces a Healing-Associated Wound Macrophage Phenotype and Improves Healing in Type 2 Diabetes

(2013) R. E. Mirza et al.   DIABETES

Discrete functions of M 2a and M 2c macrophage subsets determine their relative efficacy in treating chronic kidney disease

(2013) Junyu Lu et al.   KIDNEY INTERNATIONAL

Macrophage Depletion Impairs Corneal Wound Healing after Autologous Transplantation in Mice

(2013) Suxia Li et al.   PLoS One

Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis

(2013) Anthony O. Awojoodu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophages are required for adult salamander limb regeneration

(2013) James W. Godwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localized Delivery of Dexamethasone from Electrospun Fibers Reduces the Foreign Body Response

(2012) Nathaniel M. Vacanti et al.   BIOMACROMOLECULES

Effect of modulating macrophage phenotype on peripheral nerve repair

(2012) Nassir Mokarram et al.   BIOMATERIALS

Do Nonsteroidal Anti-Inflammatory Drugs Affect Bone Healing? A Critical Analysis

(2012) Ippokratis Pountos et al.   TheScientificWorldJOURNAL

Scaffold vascularization in vivo driven by primary human osteoblasts in concert with host inflammatory cells

(2011) Shahram Ghanaati et al.   BIOMATERIALS

Inflammation and wound healing: the role of the macrophage

(2011) Timothy J. Koh et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair

(2011) Tamar Harel-Adar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF-  promotes fracture repair by augmenting the recruitment and differentiation of muscle-derived stromal cells

(2011) G. E. Glass et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Uptake of Gold Nanorods by Primary Human Blood Phagocytes and Immunomodulatory Effects of Surface Chemistry

(2010) Matthias Bartneck et al.   ACS Nano

Hard to heal pressure ulcers (stage III–IV): Efficacy of injected activated macrophage suspension (AMS) as compared with standard of care (SOC) treatment controlled trial

(2010) Adi Zuloff-Shani et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

(2010) Chunbai He et al.   BIOMATERIALS

Macrophage Plasticity in Experimental Atherosclerosis

(2010) Jamila Khallou-Laschet et al.   PLoS One

Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling

(2010) J. D. Roh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective and Specific Macrophage Ablation Is Detrimental to Wound Healing in Mice

(2009) Rita Mirza et al.   AMERICAN JOURNAL OF PATHOLOGY

M2 Macrophages Phagocytose Rituximab-Opsonized Leukemic Targets More Efficiently than M1 Cells In Vitro

(2009) M. Leidi et al.   JOURNAL OF IMMUNOLOGY

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Protein-Mediated Assembly of Nanodiamond Hydrogels into a Biocompatible and Biofunctional Multilayer Nanofilm

(2008) Houjin Huang et al.   ACS Nano

The Local Injection of Peritoneal Macrophages Induces Neovascularization in Rat Ischemic Hind Limb Muscles

(2008) Nobuyuki Hirose et al.   CELL TRANSPLANTATION

The foreign body reaction in T-cell-deficient mice

(2008) Analiz Rodriguez et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Shape Induced Inhibition of Phagocytosis of Polymer Particles

(2008) Julie A. Champion et al.   PHARMACEUTICAL RESEARCH

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

Macrophage Phenotype as a Determinant of Biologic Scaffold Remodeling

(2008) Stephen F. Badylak et al.   TISSUE ENGINEERING PART A