Article
Fisheries
Peng Chu, Sheng Luo, Haozhe Wang, Kai Zhang, Xin Wen, Shaowu Yin, Tao Wang
Summary: This study investigated the effects of temperature and salinity interactions on apoptosis, antioxidant enzymes, and MAPK signaling pathways in the liver of T. fasciatus. Results showed that as temperature decreased, caspase 3, 7, 9 expressions and apoptosis index increased, while BCL-2 expression decreased in T. fasciatus. Salinity had a suppressive effect on GSH-PX activity, MDA concentration, caspase 3, 7, 9 expressions, and apoptosis index at low temperatures.
AQUACULTURE REPORTS
(2023)
Article
Immunology
Ting-Ting Yao, Yan Zhang, Rong-Ling He, Xin Lv, Yi-Jun He, Meng -Yu Li, Yuan-Yuan Han, Ling-Zhi Long, Guo-Liang Jiang, Xiao-Yun Cheng, Gao-Yun Hu, Qian-Bin Li, Li-Jian Tao, Jie Meng
Summary: Mefunidone effectively protects against lipopolysaccharide-induced acute lung injury by inhibiting the MAPK signaling pathway and activating the Nrf2 pathway, thereby alleviating inflammation and oxidative stress.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2022)
Article
Environmental Sciences
Tao Wang, Xiaozhen Wei, Yiru Sun, Yadong Hu, Jie Li, Xinyu Zhang, Shaowu Yin, Yonghai Shi, Yongxiang Zhu
Summary: This study revealed that exposure to CuNPs at environmental-related concentrations can induce fatty liver formation in Takifugu fasciatus, mainly through endoplasmic reticulum stress and lipid synthesis pathways. The findings provide a new understanding of the mechanisms behind fatty liver formation and contribute to the ecological safety data on CuNPs in water environments.
Article
Biotechnology & Applied Microbiology
Ying Zhang, Jie Li, Peng Chu, Ruhua Shang, Shaowu Yin, Tao Wang
Summary: A high-density genetic linkage map was constructed for T. fasciatus, and QTLs and candidate genes associated with growth and cold tolerance traits were identified. These findings are of great significance for the selection and breeding of cold-tolerant or fast-growing T. fasciatus.
Article
Pharmacology & Pharmacy
Shuai Wang, Yazhou Guo, Chen Yang, Ruijie Huang, Yuting Wen, Chunyan Zhang, Chenchen Wu, Baoyu Zhao
Summary: Swainsonine induces cell paraptosis through ER stress and MAPK signaling pathway, instead of autophagy or apoptosis, laying a theoretical foundation for the study of its toxicity mechanism.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Fisheries
Yanan Li, Zongfu Chen, Yayuan Xiao, Feng Gao, Fanbin Zhan, Zhijie Lu, Zhenpeng Huang, Xuefeng Wei, Fengping Su, Fei Shi, Li Lin, Zhendong Qin
Summary: Respiratory burst is a process of producing reactive oxygen species in response to pathogens, but excessive production can be harmful. The Keap1-Nrf2-ARE pathway plays a role in alleviating oxidative stress and maintaining cellular homeostasis. The role of Keap1 during bacterial infection in fish is not well understood.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Plant Sciences
Wangze Wu, Haobo Yang, Juan Shen, Peng Xing, Xueyan Han, Yun Dong, Guofan Wu, Sheng Zheng, Kun Gao, Ning Yang, Lina Zhang, Yujun Wu
Summary: In this study, we found that EBF1 homologs are conserved in Brassica species, but their copy numbers vary. Cold treatment activated the expression of EBF1 homologs in Brassica rapa, but the expression patterns were different among different cold-resistant varieties. Subcellular localization analysis showed that BrEBF1 is a nuclear-localized F-box protein and cold treatment induced its degradation. Overexpression of BrEBF1 enhanced cold tolerance in Arabidopsis, reduced cold-induced ROS accumulation, and increased the activity of MPK3 and MPK6 kinases. Our findings demonstrate that BrEBF1 positively regulates cold tolerance in B. rapa through the C-repeat binding factor pathway, which is associated with ROS scavenging and MPK3 and MPK6 kinase activity.
JOURNAL OF PLANT PHYSIOLOGY
(2023)
Article
Environmental Sciences
Xiangyu Cao, Mingyang Fu, Ruochen Bi, Xiaomei Zheng, Baorong Fu, Siqi Tian, Chengying Liu, Qijiu Li, Jianli Liu
Summary: Cadmium pollution can decrease cell viability, mitochondrial membrane potential, and increase ROS accumulation, leading to apoptosis of BEAS-2B cells through the activation of mitochondria-mediated intrinsic apoptosis pathway and MAPK signaling pathways.
Article
Chemistry, Medicinal
Leyi Ma, Fan Wu, Qingqing Shao, Guang Chen, Lijun Xu, Fuer Lu
Summary: This study demonstrated that baicalin can treat diabetic nephropathy (DN) by alleviating oxidative stress and inflammation, and its underlying mechanisms are associated with the activation of Nrf2-mediated antioxidant signaling pathway and the inhibition of MAPK-mediated inflammatory signaling pathway.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Medicine, Research & Experimental
Qijing Wu, Juan Chen, Xiyin Zheng, Jing Song, Lulu Yin, Hai Guo, Qian Chen, Yi Liu, Qianli Ma, Hong Zhang, Qianqian Yang
Summary: The study aimed to evaluate the protective effect of kaempferol (KPF) in doxorubicin (DOX)-induced nephrotoxicity. The results showed that KPF could alleviate DOX-induced renal injury, improve proteinuria and renal function, restore antioxidant activity in kidneys, suppress oxidative stress, and inhibit the activation of the MAPK signaling pathway. In cell experiments, KPF also inhibited DOX-induced ROS overproduction, reduced cell damage and loss of viability. Therefore, KPF may provide a viable solution to lessen renal toxicity in cancer patients receiving DOX.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Food Science & Technology
Dan Xu, Shurui Peng, Rui Guo, Lishan Yao, Haizhen Mo, Hongbo Li, Hongxin Song, Liangbin Hu
Summary: The study showed that EGCG could prevent aflatoxin contamination by inhibiting the biosynthesis of aflatoxin B-1 and reducing oxidative stress. Furthermore, EGCG inhibited AFB(1) biosynthesis through the MAPK signaling pathway and by regulating transcription factor AtfA.
Article
Fisheries
Xin Wen, Peng Chu, Jiejie Xu, Xiaozhen Wei, Dongyong Fu, Tao Wang, Shaowu Yin
Summary: The combined effects on the physiology, lipid metabolism, oxidative stress, and immunity of Takifugu fasciatus by low temperature and salinity were investigated. Results showed that certain indicators increased at low temperatures, while high salinity at high temperatures can stress the organism.
Article
Pharmacology & Pharmacy
Wei Wei, Chenjian Peng, Renjun Gu, Xiwu Yan, Jiapeng Ye, Zhuicheng Xu, Xianjie Sheng, Guicheng Huang, Yang Guo
Summary: Urolithin A can attenuate RANKL-induced osteoclastogenesis by suppressing inflammation and activating the Nrf2 signaling pathway, thereby alleviating bone loss.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Thi Van Nguyen, Chau Tuan Vo, Van Minh Vo, Cong Thuy Tram Nguyen, Thi My Pham, Chun Hua Piao, Yan Jing Fan, Ok Hee Chai, Thi Tho Bui
Summary: The plant extract from Phaeanthus vietnamensis BaN, a medicinal plant in Vietnam, has shown potential anti-inflammatory and anti-asthmatic effects. It can improve asthma symptoms, balance Th1/Th2 ratio, reduce inflammation and oxidative stress, and help restore lung function.
Article
Biochemistry & Molecular Biology
Shaoying Gong, Jiachen Zheng, Junjie Zhang, Jianchun Han
Summary: This study investigated the effect of benzo[a]pyrene (B[a]P) on the function of intestinal epithelial barrier (IEB) and the protective effect of arabinogalactan (AG) against B[a]P-induced IEB dysfunction using a Caco-2 cell monolayer model. B[a]P was found to damage the IEB integrity by inducing cell cytotoxicity, oxidative stress, pro-inflammatory cytokine secretion, down-regulation of tight junction proteins, and activation of the AhR/MAPK signaling pathway. However, AG mitigated B[a]P-induced IEB dysfunction by inhibiting oxidative stress and pro-inflammatory factor secretion.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Fisheries
Hunter S. Bailey, Ashley N. Fincannon, Lee A. Fuiman
Summary: This study investigated the transfer of fatty acids from broodstock diets to eggs and the time needed for the eggs to equilibrate to the diet in Southern flounder. The findings indicate that different diet treatments significantly affect the fatty acid composition of eggs, and it takes 8-16 weeks for the eggs to adapt to changes in the adult diet. These results are important for improving broodstock diets and feeding protocols in stock-enhancement programs.
Article
Fisheries
Yu Liu, Mingtao Lei, Hector Victor, Yan Wang
Summary: This study confirms the feasibility of replacing raw fish diet with a formulated diet in commercial farming of large yellow croaker, which can increase fish survival and yield, and reduce feed cost and body lipid deposition.
Article
Fisheries
Xiaoyan Zhang, Lize San, Yucong Yang, Yuehong Tao, Jiangong Ren, Yufeng Liu, Zhongwei He, Jiashuo Di, Ziteng Pei, Guixing Wang, Jilun Hou
Summary: Gynogenesis is an effective technique for establishing homogeneous lines and confirming potential chromosomal mechanisms of sex determination in fish. This study successfully induced gynogenetic families in Thamnaconus modestus and established a complete method for gynogenesis induction.
Article
Fisheries
Julieta C. Martinelli, Megan Considine, Helen R. Casendino, Carolyn M. Tarpey, Isadora Jimenez-Hidalgo, Jacqueline L. Padilla-Gamino, Teri L. King, Lorenz Hauser, Steven Rumrill, Chelsea L. Wood
Summary: Shell-boring polychaetes have caused significant damage to mariculture operations worldwide, particularly in the US Pacific region. This study provides a comprehensive dataset on the prevalence, species distribution, and environmental associations of these parasites, highlighting the impact of season, culturing methods, and environmental factors on infestation.
Article
Fisheries
Juan Gao, Xueshan Li, Kangle Lu, Kai Song, Jian Zhang, Ling Wang, Chunxiao Zhang
Summary: This study investigated the effects of dietary protein levels on growth performance, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog tadpoles. The optimal dietary protein level for bullfrog tadpoles was estimated to be 42.49%-46.50% of the diet.
Article
Fisheries
Qiang Li, Lijun Duan, Dongsheng Jin, Yuxin Chen, Yirong Lou, Qianjin Zhou, Zhongjie Xu, Fangjie Chen, Hongxian Chen, Guizong Xu, Maocang Yan, Guanjun Yang, Jianfei Lu, Yanjun Zhang, Jiong Chen
Summary: This study developed a centrifugal microfluidic chip with on-chip RPA to detect five pathogenic microorganisms. The chip enabled the parallel analysis of six genetic markers from a single sample and allowed for the highly automated detection of multiple samples. Compared with PCR and DNA sequencing, the on-chip RPA assay showed high sensitivity and specificity for detecting multiple pathogens in shrimp aquaculture.
Article
Fisheries
Xingchen Huo, Pengxu Wang, Fengxia Zhao, Qian Liu, Qingqing Tian, Lingjie Tang, Maolin Lv, Zhaohui Wei, Chunrong Yang, Jianguo Su
Summary: Bacterial diseases in aquaculture ponds have negative effects on sustainable development. The use of composite I20 biotherapy has been shown to effectively treat bacterial diseases in bullfrog ponds, providing a new strategy for controlling bacterial diseases in aquaculture.
Article
Fisheries
Peng Yin, Takaya Saito, Per Gunnar Fjelldal, Bjorn Tharandur Bjornsson, Sofie Charlotte Remo, Sandeep Sharma, Rolf Erik Olsen, Kristin Hamre
Summary: This study aims to investigate the effect of seasonal changes in temperature and photoperiod on the redox metabolism of Atlantic salmon at the molecular level. The research findings suggest that the changing photoperiod and temperature influenced the redox metabolism of Atlantic salmon, highlighting the importance of oxidative status in the ecological implications.
Article
Fisheries
Nicholas Oppong Mensah, Jeffery Kofi Asare, Emmanuel Tetteh-Doku Mensah, Ernest Christlieb Amrago, Frank Osei Tutu, Anthony Donkor
Summary: This study investigates aquaculture farmers' preference for climate-smart aquaculture insurance products, the challenges they face, and their preferred insurance coverage. The results show that farmers prefer Climate-Induced Aquaculture Stock Mortality Insurance and the most significant constraint is the delay in claim settlement.
Article
Fisheries
Qiu-Ping Chai, Pei Wu, Wei-Dan Jiang, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Lin Feng, Xiao-Qiu Zhou
Summary: The study found that appropriate levels of potassium diformate (KDF) can enhance the immune defense and mediate the inflammatory process in fish, possibly through the regulation of T cell differentiation via JAK-STAT and NF-kappa B signaling pathways.
Article
Fisheries
Tian Zhu, Haomin Jia, Haopeng Zhang, Yujing Xiao, Cui Han, Jiaxin Yang
Summary: Chicken manure has significant effects on the cultivation of Chlorella and rotifers. The optimal amount of chicken manure extract for continuous cultivation is 10 mLL-1. Chicken manure can promote the growth of Chlorella and improve the fatty acid composition, indirectly enhancing the growth condition and fatty acid content of rotifers.
Article
Fisheries
Zheng Luo, Yang Yu, Zhenning Bao, Fuhua Li
Summary: This study analyzed the heritability and genetic correlation of two growth traits in Pacific white shrimp and evaluated the genomic prediction using different genomic selection models. The results showed that the NeuralNet model had the highest prediction accuracy and better prospects for predicting shrimp growth traits.
Article
Fisheries
Alberto Ruiz, Ignasi Sanahuja, Karl B. Andree, Dolors Furones, Paul G. Holhorea, Josep A. Calduch-Giner, Jose J. Pastor, Marc Vinas, Jaume Perez-Sanchez, Sofia Morais, Enric Gisbert
Summary: Supplementing diets with a combination of spice oleoresins can reduce lipid accumulation and inflammation in farmed fish. The combination of spice oleoresins also has an immunomodulatory effect on the fish's intestinal immune system, potentially offering anti-inflammatory benefits.
Article
Fisheries
Beibei Zhao, Renhui Mei, Le Li, Di Hu, Lei Li
Summary: This study reveals that JfCXCL8_L1a and JfCXCL8_L1b have different immune pathways, and JfCXCL8_L1b plays a significant role in enhancing the adaptive immunity of T cell-dependent antigen.
Article
Fisheries
Yuhang Liu, Danying Cao, Nan Wu, Xuyang Zhao, Qingsong Zhu, Lian Su, Fatima Altaf, Qianqian Zhang, Haokun Liu, Yongming Li, Bruno Hamish Unger, Yingyin Cheng, Wanting Zhang, Aihua Li, Yaping Wang, Xiao-Qin Xia
Summary: Based on previous research, sinomenine has been found to protect mucosal immunity in farmed fish species by preventing intestinal pathological changes and regulating gene expression related to inflammation. It also enhances immune homeostasis and controls the growth of pathogenic bacteria.