Identification of Novel Mutations Contributing to Azole Tolerance of Aspergillus fumigatus through In Vitro Exposure to Tebuconazole

AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus

(2019) Sanjoy Paul et al.   mBio

Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanism

(2019) Eloise Ballard et al.   FUNGAL GENETICS AND BIOLOGY

Update and recent advances on azole resistance mechanisms in

(2019) Alba Pérez-Cantero et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Prospective survey of Aspergillus species isolated from clinical specimens and their antifungal susceptibility: A five-year single-center study in Japan

(2019) Takahito Toyotome et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Exploring the molecular mechanism of azole resistance in Aspergillus fumigatus

(2019) P. Chen et al.   JOURNAL DE MYCOLOGIE MEDICALE

In-host microevolution of Aspergillus fumigatus : A phenotypic and genotypic analysis

(2018) Eloise Ballard et al.   FUNGAL GENETICS AND BIOLOGY

Comparative genome analysis of Aspergillus flavus clinically isolated in Japan

(2018) Takahito Toyotome et al.   DNA RESEARCH

Tebuconazole induces triazole-resistance in Aspergillus fumigatus in liquid medium and soil

(2018) Ning Cui et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Fungicides induced triazole-resistance in Aspergillus fumigatus associated with mutations of TR46/Y121F/T289A and its appearance in agricultural fields

(2017) Jingbei Ren et al.   JOURNAL OF HAZARDOUS MATERIALS

Evolution of cross-resistance to medical triazoles in Aspergillus fumigatus through selection pressure of environmental fungicides

(2017) Jianhua Zhang et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

(2017) Jianhua Zhang et al.   mBio

A putative mitochondrial calcium uniporter in A. fumigatus contributes to mitochondrial Ca2+ homeostasis and stress responses

(2016) Jinxing Song et al.   FUNGAL GENETICS AND BIOLOGY

Azole susceptibility in clinical and environmental isolates of Aspergillus fumigatus from eastern Hokkaido, Japan

(2016) Takahito Toyotome et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Identification ofAspergillus fumigatusmultidrug transporter genes and their potential involvement in antifungal resistance

(2016) Isabelle Meneau et al.   MEDICAL MYCOLOGY

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

(2016) Fabio Gsaller et al.   PLoS Pathogens

Mitochondrial Complex I Is a Global Regulator of Secondary Metabolism, Virulence and Azole Sensitivity in Fungi

(2016) Mike Bromley et al.   PLoS One

Sensitisation of an Azole-Resistant Aspergillus fumigatus Strain containing the Cyp51A-Related Mutation by Deleting the SrbA Gene

(2016) Daisuke Hagiwara et al.   Scientific Reports

Azole Resistance inAspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?

(2015) Paul E. Verweij et al.   CLINICAL INFECTIOUS DISEASES

Genome sequence comparison of Aspergillus fumigatus strains isolated from patients with pulmonary aspergilloma and chronic necrotizing pulmonary aspergillosis

(2015) Azusa Takahashi-Nakaguchi et al.   MEDICAL MYCOLOGY

Whole-Genome Comparison of Aspergillus fumigatus Strains Serially Isolated from Patients with Aspergillosis

(2014) D. Hagiwara et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The clinical spectrum of pulmonary aspergillosis

(2014) C. Kosmidis et al.   THORAX

Prediction of antibiotic resistance by gene expression profiles

(2014) Shingo Suzuki et al.   Nature Communications

ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

(2014) Dawoon Chung et al.   PLoS Pathogens

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus 

(2013) Marcin G. Fraczek et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Structural Requirements for Sterol Regulatory Element-binding Protein (SREBP) Cleavage in Fission Yeast

(2013) Rocky Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlation between Triazole Treatment History and Susceptibility in Clinically Isolated Aspergillus fumigatus

(2012) Masato Tashiro et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of novel genes conferring altered azole susceptibility in Aspergillus fumigatus

(2012) Paul Bowyer et al.   FEMS MICROBIOLOGY LETTERS

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Triazole Fungicides Can Induce Cross-Resistance to Medical Triazoles in Aspergillus fumigatus

(2012) Eveline Snelders et al.   PLoS One

The Molecular Diversity of Adaptive Convergence

(2012) O. Tenaillon et al.   SCIENCE

The Aspergillus Genome Database (AspGD): recent developments in comprehensive multispecies curation, comparative genomics and community resources

(2011) M. B. Arnaud et al.   NUCLEIC ACIDS RESEARCH

Factors Associated with Mortality in Transplant Patients with Invasive Aspergillosis

(2010) John W. Baddley et al.   CLINICAL INFECTIOUS DISEASES

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?

(2009) Paul E Verweij et al.   LANCET INFECTIOUS DISEASES

Clinical Itraconazole-Resistant Strains of Aspergillus fumigatus, Isolated Serially from a Lung Aspergilloma Patient with Pulmonary Tuberculosis, can be Detected with Real-Time PCR Method

(2009) Hui Xu et al.   MYCOPATHOLOGIA