Alternative Splicing and Liver Disease

Alternative RNA Splicing in Fatty Liver Disease

(2021) Panyisha Wu et al.   Frontiers in Endocrinology

Genome-Wide Transcriptional Analysis Reveals Alternative Splicing Event Profiles in Hepatocellular Carcinoma and Their Prognostic Significance

(2020) Yongfu Xiong et al.   Frontiers in Genetics

Alternative Splicing in Hepatocellular Carcinoma

(2020) Seung Eun Lee et al.   Cellular and Molecular Gastroenterology and Hepatology

Perspective in Alternative Splicing Coupled to Nonsense-Mediated mRNA Decay

(2020) Juan F. García-Moreno et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis

(2020) Olivier Govaere et al.   Science Translational Medicine

FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner

(2020) Xiaonan Su et al.   Cell Death Discovery

EDA fibronectin–TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis

(2019) Alessandro Malara et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dysregulation of the splicing machinery is associated to the development of non-alcoholic fatty liver disease

(2019) Mercedes del Río-Moreno et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

From NASH to HCC: current concepts and future challenges

(2019) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Degradation of splicing factor SRSF3 contributes to progressive liver disease

(2019) Deepak Kumar et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of alternative splicing in obesity-induced hypertension

(2019) Zodwa Dlamini et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

RNA Splicing by the Spliceosome

(2019) Max E. Wilkinson et al.   Annual Review of Biochemistry

The Expanding Landscape of Alternative Splicing Variation in Human Populations

(2018) Eddie Park et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hepatic Knockdown of Splicing Regulator Slu7 Ameliorates Inflammation and Attenuates Liver Injury in Ethanol-Fed Mice

(2018) Jiayou Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

The splicing code

(2018) Marco Baralle et al.   BIOSYSTEMS

Transcriptome-Wide Analysis Reveals the Landscape of Aberrant Alternative Splicing Events in Liver Cancer

(2018) Shengli Li et al.   HEPATOLOGY

Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration

(2018) Sushant Bangru et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Insulin Receptor Isoforms in Cancer

(2018) Veronica Vella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alternative splicing as a regulator of development and tissue identity

(2017) Francisco E. Baralle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718

(2017) Mie Andersen et al.   PLoS One

Alternative splicing regulates distinct subcellular localization of Epithelial splicing regulatory protein 1 (Esrp1) isoforms

(2017) Yueqin Yang et al.   Scientific Reports

The hnRNP family: insights into their role in health and disease

(2016) Thomas Geuens et al.   HUMAN GENETICS

Fibronectin expression is critical for liver fibrogenesis in vivo and in vitro

(2016) Xiao-Ya Liu et al.   Molecular Medicine Reports

Identification and characterization of a unique role for EDB fibronectin in phagocytosis

(2015) Sabrina Kraft et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The alternatively spliced fibronectin CS1 isoform regulates IL-17A levels and mechanical allodynia after peripheral nerve injury

(2015) Huaqing Liu et al.   Journal of Neuroinflammation

Identification of important long non-coding RNAs and highly recurrent aberrant alternative splicing events in hepatocellular carcinoma through integrative analysis of multiple RNA-Seq datasets

(2015) Lu Zhang et al.   MOLECULAR GENETICS AND GENOMICS

ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation

(2015) Amruta Bhate et al.   Nature Communications

PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells

(2015) Jihua Guo et al.   Scientific Reports

Deletion of serine/arginine-rich splicing factor 3 in hepatocytes predisposes to hepatocellular carcinoma in mice

(2014) Supriya Sen et al.   HEPATOLOGY

Splicing regulator SLU7 is essential for maintaining liver homeostasis

(2014) María Elizalde et al.   JOURNAL OF CLINICAL INVESTIGATION

Toll-Like Receptor Signaling Pathways

(2014) Takumi Kawasaki et al.   Frontiers in Immunology

Function of alternative splicing

(2012) Olga Kelemen et al.   GENE

A Fibronectin-Independent Mechanism of Collagen Fibrillogenesis in Adult Liver Remodeling

(2011) Kei Moriya et al.   GASTROENTEROLOGY

RNA-Seq Analyses Generate Comprehensive Transcriptomic Landscape and Reveal Complex Transcript Patterns in Hepatocellular Carcinoma

(2011) Qichao Huang et al.   PLoS One

Fibronectin: Functional character and role in alcoholic liver disease

(2011) Razia S Aziz-Seible   WORLD JOURNAL OF GASTROENTEROLOGY

Deciphering the splicing code

(2010) Yoseph Barash et al.   NATURE

Predicting Fibrosis Worsening in Obese Patients With NASH Through Parenchymal Fibronectin, HOMA-IR and Hypertension

(2009) Paolo Sorrentino et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation

(2009) Melissa J. Moore et al.   CELL

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis

(2008) Goutham Narla et al.   JOURNAL OF CLINICAL INVESTIGATION

SRp20 and CUG-BP1 Modulate Insulin Receptor Exon 11 Alternative Splicing

(2008) S. Sen et al.   MOLECULAR AND CELLULAR BIOLOGY

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Absence of regulated splicing of fibronectin EDA exon reduces atherosclerosis in mice

(2007) Vladimir R. Babaev et al.   ATHEROSCLEROSIS