Second Near‐Infrared Light‐Activatable Polymeric Nanoantagonist for Photothermal Immunometabolic Cancer Therapy

Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

(2021) Zhusheng Huang et al.   Nature Communications

A Polymer Multicellular Nanoengager for Synergistic NIR‐II Photothermal Immunotherapy

(2021) Cheng Xu et al.   ADVANCED MATERIALS

In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy

(2021) Yue Yin et al.   NANO LETTERS

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer

(2021) Yuyan Jiang et al.   Nature Communications

Selenium‐Containing Nanoparticles Combine the NK Cells Mediated Immunotherapy with Radiotherapy and Chemotherapy

(2020) Shiqian Gao et al.   ADVANCED MATERIALS

Modularly Designed Peptide Nanoprodrug Augments Antitumor Immunity of PD-L1 Checkpoint Blockade by Targeting Indoleamine 2,3-Dioxygenase

(2020) Xuexiang Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rationally Designed Polymer Conjugate for Tumor-Specific Amplification of Oxidative Stress and Boosting Antitumor Immunity

(2020) Sheng Ma et al.   NANO LETTERS

Reversible Thermochromic Nanoparticles Composed of a Eutectic Mixture for Temperature-Controlled Photothermal Therapy

(2020) Song Shen et al.   NANO LETTERS

Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy

(2020) Hongzhang Deng et al.   NANO LETTERS

Near-infrared optogenetic engineering of photothermal nanoCRISPR for programmable genome editing

(2020) Xiaohong Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

(2020) Bruno Bockorny et al.   NATURE MEDICINE

Moving towards personalized treatments of immune-related adverse events

(2020) Khashayar Esfahani et al.   Nature Reviews Clinical Oncology

Transformable hybrid semiconducting polymer nanozyme for second near-infrared photothermal ferrotherapy

(2020) Yuyan Jiang et al.   Nature Communications

Photoactivatable Protherapeutic Nanomedicine for Cancer

(2020) Yan Zhang et al.   ADVANCED MATERIALS

Rational Design of Conjugated Small Molecules for Superior Photothermal Theranostics in the NIR‐II Biowindow

(2020) Shengliang Li et al.   ADVANCED MATERIALS

Planar plus twisted molecular structure leads to high brightness of semiconducting polymer nanoparticles for NIR-IIa fluorescence imaging

(2020) Shunjie Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Clinical development and potential of photothermal and photodynamic therapies for cancer

(2020) Xingshu Li et al.   Nature Reviews Clinical Oncology

Second Near‐Infrared Photothermal Semiconducting Polymer Nanoadjuvant for Enhanced Cancer Immunotherapy

(2020) Jingchao Li et al.   ADVANCED MATERIALS

Activatable Polymer Nanoenzymes for Photodynamic Immunometabolic Cancer Therapy

(2020) Ziling Zeng et al.   ADVANCED MATERIALS

Activatable NIR‐II Plasmonic Nanotheranostics for Efficient Photoacoustic Imaging and Photothermal Cancer Therapy

(2020) Chunyu Zhou et al.   ADVANCED MATERIALS

Considerations for designing preclinical cancer immune nanomedicine studies

(2020) Wen Jiang et al.   Nature Nanotechnology

Navigating metabolic pathways to enhance antitumour immunity and immunotherapy

(2019) Xiaoyun Li et al.   Nature Reviews Clinical Oncology

Photoactivatable Organic Semiconducting Pro-nanoenzymes

(2019) Jingchao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Semiconducting Polymer Nano-prodrug for Hypoxia-Activated Photodynamic Cancer Therapy

(2019) Dong Cui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox-Activatable and Acid-Enhanced Nanotheranostics for Second Near-Infrared Photoacoustic Tomography and Combined Photothermal Tumor Therapy

(2019) Zhimin Wang et al.   ACS Nano

Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance

(2019) Filipe Martins et al.   Nature Reviews Clinical Oncology

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

Nanoenabled Reversal of IDO1-Mediated Immunosuppression Synergizes with Immunogenic Chemotherapy for Improved Cancer Therapy

(2019) Hua Huang et al.   NANO LETTERS

NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices

(2019) Hongqian Chu et al.   Nature Communications

Bio-inspired drug-dominated supramolecular nanocomplex based on low molecular weight heparin for progressive tumor therapy

(2019) Yao Yu et al.   CARBOHYDRATE POLYMERS

Inhibitory receptors and ligands beyond PD-1, PD-L1 and CTLA-4: breakthroughs or backups

(2019) Lawrence P. Andrews et al.   NATURE IMMUNOLOGY

Furin-mediated intracellular self-assembly of olsalazine nanoparticles for enhanced magnetic resonance imaging and tumour therapy

(2019) Yue Yuan et al.   NATURE MATERIALS

Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer

(2019) Lawrence Fong et al.   Cancer Discovery

Semiconducting Polymer Dots with Dual-Enhanced NIR-IIa Fluorescence for Through-Skull Mouse-Brain Imaging

(2019) Zhe Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Magnetic-induced graphene quantum dots for imaging-guided photothermal therapy in the second near-infrared window

(2019) Hongji Liu et al.   BIOMATERIALS

The Untapped Opportunity and Challenge of Immunometabolism: A New Paradigm for Drug Discovery

(2019) Claire Mazumdar et al.   Cell Metabolism

Self-Propelled Gemini-like LMWH-Scaffold Nanodrugs for Overall Tumor Microenvironment Manipulation via Macrophage Reprogramming and Vessel Normalization

(2019) Cheng Xu et al.   NANO LETTERS

Development of endogenous enzyme-responsive nanomaterials for theranostics

(2018) Jing Mu et al.   CHEMICAL SOCIETY REVIEWS

Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery

(2018) Li Tang et al.   NATURE BIOTECHNOLOGY

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer

(2018) Jutaek Nam et al.   Nature Communications

Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

(2018) Kuangda Lu et al.   Nature Biomedical Engineering

Large-Pore Mesoporous-Silica-Coated Upconversion Nanoparticles as Multifunctional Immunoadjuvants with Ultrahigh Photosensitizer and Antigen Loading Efficiency for Improved Cancer Photodynamic Immunotherapy

(2018) Binbin Ding et al.   ADVANCED MATERIALS

Tumor Microenvironment-Responsive Ultrasmall Nanodrug Generators with Enhanced Tumor Delivery and Penetration

(2018) Pengfei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Two-Dimensional Biodegradable Niobium Carbide (MXene) for Photothermal Tumor Eradication in NIR-I and NIR-II Biowindows

(2017) Han Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Broadband Absorbing Semiconducting Polymer Nanoparticles for Photoacoustic Imaging in Second Near-Infrared Window

(2017) Yuyan Jiang et al.   NANO LETTERS

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells

(2017) Yuying Liu et al.   Nature Communications

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

(2016) Almut Brand et al.   Cell Metabolism

Semiconducting Polymer Nanobioconjugates for Targeted Photothermal Activation of Neurons

(2016) Yan Lyu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photodynamic Therapy Mediated by Nontoxic Core–Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer

(2016) Xiaopin Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody

(2016) Chao Wang et al.   NANO LETTERS

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice

(2014) Kanyi Pu et al.   Nature Nanotechnology