DNA Origami Penetration in Cell Spheroid Tissue Models is Enhanced by Wireframe Design

Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release

(2021) Heini Ijäs et al.   NUCLEIC ACIDS RESEARCH

Design, optimization and analysis of large DNA and RNA nanostructures through interactive visualization, editing and molecular simulation

(2020) Erik Poppleton et al.   NUCLEIC ACIDS RESEARCH

Progress toward Understanding the Interactions between DNA Nanostructures and the Cell

(2019) Yee Ting Elaine Chiu et al.   Small

Penetration and Uptake of Nanoparticles in 3D Tumor Spheroids

(2019) Aleksandra Tchoryk et al.   BIOCONJUGATE CHEMISTRY

Role of Nanoparticle Mechanical Properties in Cancer Drug Delivery

(2019) Yue Hui et al.   ACS Nano

Tailoring the Mechanical Stiffness of DNA Nanostructures Using Engineered Defects

(2019) Chanseok Lee et al.   ACS Nano

Understanding the Effects of Nanocapsular Mechanical Property on Passive and Active Tumor Targeting

(2018) Yue Hui et al.   ACS Nano

Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles

(2018) Jacob W. Myerson et al.   ADVANCED MATERIALS

Modulating the rigidity of nanoparticles for tumor penetration

(2018) Hongzhang Deng et al.   CHEMICAL COMMUNICATIONS

Visualization of the Cellular Uptake and Trafficking of DNA Origami Nanostructures in Cancer Cells

(2018) Pengfei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape

(2018) Maartje M. C. Bastings et al.   NANO LETTERS

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

DNA Nanostructures at the Interface with Biology

(2018) Katherine E. Bujold et al.   Chem

Effects of Design Choices on the Stiffness of Wireframe DNA Origami Structures

(2018) Erik Benson et al.   ACS Nano

The mobility of packaged phage genome controls ejection dynamics

(2018) Alex Evilevitch   eLife

Sequence-programmable covalent bonding of designed DNA assemblies

(2018) Thomas Gerling et al.   Science Advances

Coarse-grained modelling of the structural properties of DNA origami

(2018) Benedict E K Snodin et al.   NUCLEIC ACIDS RESEARCH

Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

(2017) Nandhini Ponnuswamy et al.   Nature Communications

Design and Synthesis of Triangulated DNA Origami Trusses

(2016) Michael Matthies et al.   NANO LETTERS

Designer nanoscale DNA assemblies programmed from the top down

(2016) R. Veneziano et al.   SCIENCE

Intracellular Delivery of a Planar DNA Origami Structure by the Transferrin-Receptor Internalization Pathway

(2016) David H. Schaffert et al.   Small

DNA nanotubes as intracellular delivery vehicles in vivo

(2015) Sabine Sellner et al.   BIOMATERIALS

DNA rendering of polyhedral meshes at the nanoscale

(2015) Erik Benson et al.   NATURE

Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model

(2015) Patrick D. Halley et al.   Small

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Tunable Rigidity of (Polymeric Core)-(Lipid Shell) Nanoparticles for Regulated Cellular Uptake

(2014) Jiashu Sun et al.   ADVANCED MATERIALS

Stiffness-Dependent In Vitro Uptake and Lysosomal Acidification of Colloidal Particles

(2014) Raimo Hartmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Quantification of cellular uptake of DNA nanostructures by qPCR

(2014) Anders Hauge Okholm et al.   METHODS

Doxorubicin, DNA torsion, and chromatin dynamics

(2013) Fan Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Coarse-graining DNA for simulations of DNA nanotechnology

(2013) Jonathan P. K. Doye et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

In situ structure and dynamics of DNA origami determined through molecular dynamics simulations

(2013) J. Yoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Origami Delivery System for Cancer Therapy with Tunable Release Properties

(2012) Yong-Xing Zhao et al.   ACS Nano

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures

(2011) Verena J. Schüller et al.   ACS Nano

Direct Mechanical Measurements Reveal the Material Properties of Three-Dimensional DNA Origami

(2011) Dominik J. Kauert et al.   NANO LETTERS

Multilayer DNA Origami Packed on a Square Lattice

(2009) Yonggang Ke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of DNA into nanoscale three-dimensional shapes

(2009) Shawn M. Douglas et al.   NATURE

Rapid prototyping of 3D DNA-origami shapes with caDNAno

(2009) Shawn M. Douglas et al.   NUCLEIC ACIDS RESEARCH

Folding DNA into Twisted and Curved Nanoscale Shapes

(2009) H. Dietz et al.   SCIENCE