Article
Chemistry, Inorganic & Nuclear
Hailong Yan, Jinbing Cheng, Zuxue Bai, Tao Peng, Yang Lu, Jang-Kyo Kim, Yongsong Luo
Summary: In this study, a NiMn2O4@MXene composite with a crumpled surface was fabricated by a hydrothermal method and developed dip-coating method, resulting in improved electrode specific capacitance and retention rate. Additionally, an asymmetrical device was assembled, demonstrating ultra-high energy density.
DALTON TRANSACTIONS
(2021)
Article
Nanoscience & Nanotechnology
Xuelian Zhang, Haohan Chen, Siqi Cheng, Feng Guo, Wenjing Jie, Jianhua Hao
Summary: This study investigates the resistive switching characteristics, synaptic functions, and neuromorphic computing of memristors based on two-dimensional MXene Ti3C2 nanosheets. The results show that both digital and analog resistive switching behaviors can coexist in these memristors depending on the magnitude of operation voltage. Additionally, the artificial synapses based on these memristors exhibit basic synaptic functions and successfully emulate the learning-forgetting experience. Moreover, the artificial synapses can be used to construct an artificial neural network for image recognition.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Shabi Abbas Zaidi, Hanan Sheikh, Muna Al-Mahasna, Fathiya Elsin
Summary: A simple and facile method was developed to achieve controlled oxidation and enhance the surface area of MXene nanosheets for the efficient sensing of ascorbic acid (AA). The crumpled MXene showed anatase phase, porosity, and improved surface area, and was successfully used to determine AA with a linear concentration range of 300 μM to 0.005 μM and a detection limit (LOD) of 2 nM. The developed electrochemical sensor exhibited excellent reproducibility, a long shelf life, and satisfactory selectivity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Physics, Applied
Sabeen Fatima, Rabia Tahir, Syed Rizwan
Summary: This study presents a novel MXene flexible memory device with substrate-free growth in ambient conditions, which has attracted interest in current innovation due to its high nonvolatile storage, light weight, smart, portable, and better functioned memories. The synthesis of MXene sheets was confirmed through surface morphology, elemental and structural analysis. X-ray diffraction, Raman, and FTIR spectra showed the presence of TiO2 inside FE-Ti3C2Tx MXene, which contributed toward the ferroelectric behavior of MXene.
APPLIED PHYSICS LETTERS
(2023)
Review
Neurosciences
Christophe Mulle, Valerie Crepel
Summary: Kainate receptors (KARs) are ionotropic glutamate receptors that play important physiological roles in neuronal circuits, regulating EPSCs as post-synaptic receptors and controlling ion channels through non-canonical metabotropic actions. KARs, activated by endogenous glutamate, modulate neuronal circuit activity and plasticity under normal physiological conditions.
Article
Cell Biology
Katarzyna M. Grochowska, Marit Sperveslage, Rajeev Raman, Antonio V. Failla, Dawid Glow, Christian Schulze, Laura Laprell, Boris Fehse, Michael R. Kreutz
Summary: The complex morphology of neurons presents a challenge for proteostasis, but recent studies have shown that mature lysosomes can be found in dendrites and release their content through fusion with the plasma membrane. These dendritic lysosomes are heterogeneous in composition and only those containing LAMP2A and LAMP2B exhibit activity-dependent motility. They dock near NMDAR receptors via an association with SAP102/Dlg3, and NMDAR activation decreases lysosome motility and promotes fusion with the membrane. Chaperone-mediated autophagy supplies content that is released through lysosome exocytosis, enabling local disposal of aggregation-prone proteins.
Article
Biochemistry & Molecular Biology
Adel E. Khairullin, Sergey N. Grishin, Ayrat U. Ziganshin
Summary: ATP and adenosine play important roles in regulating the release of acetylcholine at the neuro-muscular synapse. ATP acts through phospholipase C dependent processes, while adenosine has both negative and positive effects mediated by different receptor mechanisms.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2023)
Article
Zoology
Natalia M. Biserova, Alfia R. Mustafina, Olga Raikova
Summary: A novel complex neuro-glandular brain structure associated with sensory elements has been discovered in the plerocercoid parasite of Gadus morua from the White Sea. This structure, consisting of both nervous and glandular elements, is suggested as a model for the Diphyllobothriidae family. Significant differences in the architecture of the plerocercoid brain at the family level have been observed within the order Diphyllobothriidea. Serotonin, FMRFamide, and GABA-like immunoreactive neurons are present in various parts of the parasite.
Article
Materials Science, Multidisciplinary
Yifan Wang, Yuqin Wan, Xiangqi Meng, Lei Jiang, Hao Wei, Xinyue Zhang, Ning Ma
Summary: This article introduces a photo-thermal distillation device, which combines chitosan aerogel with a bio-inspired wood-like oriented porous structure and Ti3C2Tx two-dimensional nanosheets coated with polyethyleneimine on the surface. The device has rapid water transport capacity and high-efficiency photo-thermal conversion performance, and can be used for efficient production of clean fresh water.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Electrochemistry
P. Baraneedharan, D. Shankari, A. Arulraj, Percy J. Sephra, R. V. Mangalaraja, Mohammad Khalid
Summary: This paper reviews the advantages and applications of MXene materials in gas sensing. By fine-tuning the characteristics of MXene, it can be suitable for sensor design, and the latest progress and challenges in FET-based gas sensors are thoroughly examined.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Review
Immunology
Cigdem Acioglu, Robert F. Heary, Stella Elkabes
Summary: Toll-like receptors (TLRs) are innate immune receptors expressed in immune cells, glia, and neurons, playing important roles in host defense and inflammation. The role of neuronal TLRs in central nervous system diseases and injuries has been underappreciated, and future research is needed to understand their specific contributions in these pathologies.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Review
Materials Science, Multidisciplinary
Xuwen Xia, Wen Huang, Pengjie Hang, Tao Guo, Yong Yan, Jianping Yang, Deren Yang, Xuegong Yu, Xing'ao Li
Summary: Neuromorphic computing is a powerful tool to overcome the von Neumann bottleneck by processing large amounts of information in parallel. The construction of artificial neural networks (ANNs) and reservoir computing (RC) are common approaches to realize neuromorphic computing and have shown great potential in various applications. Recent research has focused on investigating 2D-material-based memristive systems and their applications in ANN and RC due to their unique properties. This review systematically explores the current status and future directions of 2D-material-based synaptic devices, promoting their utilization in neuromorphic computing.
ACS MATERIALS LETTERS
(2023)
Review
Materials Science, Multidisciplinary
Xuwen Xia, Wen Huang, Pengjie Hang, Tao Guo, Yong Yan, Jianping Yang, Deren Yang, Xuegong Yu, Xing'ao Li
Summary: Neuromorphic computing is a powerful tool to tackle the von Neumann bottleneck by processing information in parallel. Artificial neural networks (ANN) and reservoir computing (RC) are common approaches to neuromorphic computing, with 2D-material-based memristive systems being widely investigated due to their unique properties. This review discusses the properties, applications, and working mechanisms of 2D-material-based synaptic devices, and analyzes their performance, progress, and future development directions in neuromorphic computing.
ACS MATERIALS LETTERS
(2023)
Review
Neurosciences
Csaba Cserep, Balazs Posfai, Adam Denes
Summary: Microglia establishing direct contact with neurons play a crucial role in regulating neuronal responses and fate, contributing significantly to brain diseases.
Article
Biochemistry & Molecular Biology
Lubna H. Tahtamouni, Sydney A. Alderfer, Thomas B. Kuhn, Laurie S. Minamide, Soham Chanda, Michael R. Ruff, James R. Bamburg
Summary: This study demonstrates that neurons differentiated from human-induced pluripotent stem cells provide a robust model for studying the formation of cofilactin rods. The formation of rods in response to disease-associated factors like A beta depends on a pathway involving cellular prion protein, NADPH oxidase, and cytokine/chemokine receptors. The absence of glia allows for easier observation of rods, revealing that neurons mature and fire action potentials without forming functional synapses. These findings are important for understanding and developing treatments for dementias caused by various proteinopathies.
Article
Chemistry, Multidisciplinary
Xiaobing Yan, Yifei Pei, Huawei Chen, Jianhui Zhao, Zhenyu Zhou, Hong Wang, Lei Zhang, Jingjuan Wang, Xiaoyan Li, Cuiya Qin, Gong Wang, Zuoao Xiao, Qianlong Zhao, Kaiyang Wang, Hui Li, Deliang Ren, Qi Liu, Hao Zhou, Jingsheng Chen, Peng Zhou
ADVANCED MATERIALS
(2019)
Article
Chemistry, Multidisciplinary
Xiaobing Yan, Kaiyang Wang, Jianhui Zhao, Zhenyu Zhou, Hong Wang, Jingjuan Wang, Lei Zhang, Xiaoyan Li, Zuoao Xiao, Qianlong Zhao, Yifei Pei, Gong Wang, Cuiya Qin, Hui Li, Jianzhong Lou, Qi Liu, Peng Zhou
Article
Biochemistry & Molecular Biology
Shihui Hu, Yunfang Jia
Article
Nanoscience & Nanotechnology
Kaiyang Wang, Liteng Li, Rujie Zhao, Jianhui Zhao, Zhenyu Zhou, Jingjuan Wang, Hong Wang, Baokun Tang, Chao Lu, Jianzhong Lou, Jingsheng Chen, Xiaobing Yan
ADVANCED ELECTRONIC MATERIALS
(2020)
Article
Chemistry, Analytical
Shihui Hu, Rong Zhang, Yunfang Jia
Article
Chemistry, Multidisciplinary
Dong Dong, Jizhao Zhang, Runshi Zhang, Fang Li, Yueguo Li, Yunfang Jia
Article
Chemistry, Physical
Kaiyang Wang, Jingsheng Chen, Xiaobing Yan
Summary: This study presents a facile method to improve the electronic performance of MXene Ti3C2 memristor by Ag nanoparticle doping. The doping method exhibits bidirectional continuous current transition behavior and has the potential to implement decimal arithmetic operations.
Article
Chemistry, Multidisciplinary
Fang Li, Jizhao Zhang, Shihui Hu, Yunfang Jia
Summary: This study presents a carbon-based light addressable potentiometric sensor (C-LAPS) using a combination of carbon dots (CDs) and liquid exfoliated graphene (LEG). The electronic and photoelectronic features of C-LAPS are measured and compared with electrodes decorated with pure CDs and LEG. The feasibility for biological application is justified using an immune reaction as a proof of concept, showing improved linear responses compared to traditional semiconductor-based LAPS.
Article
Chemistry, Multidisciplinary
Rong Zhang, Yunfang Jia
Summary: A portable salivary cortisol test setup based on liquid gate graphene field effect transistor (Lg-GFET) was developed for rapid and accurate detection of salivary cortisol levels, demonstrating good sensitivity, selectivity, and robustness, and successfully applied to tracking circadian rhythm.
Article
Chemistry, Multidisciplinary
Xiaobing Yan, Haidong He, Gongjie Liu, Zhen Zhao, Yifei Pei, Pan Liu, Jianhui Zhao, Zhenyu Zhou, Kaiyang Wang, Hongwei Yan
Summary: This study presents a silicon-based memristor with an epitaxial ferroelectric film, which enables multi-value storage, algebraic operations, and neural computing chip applications. The film exhibits optimized ferroelectric polarization reversal and epitaxial structure, leading to improved resistance characteristics and robust endurance. Experimental results demonstrate successful simulation of synaptic plasticity and algebraic operations by controlling pulse voltage. The memristor achieves high recognition rates in identifying the CIFAR-10 dataset.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Physical
Kaiyang Wang, Yunfang Jia, Xiaobing Yan
Summary: This study presents a chip-like flexible biomimetic afferent nervous system (ANS) device that combines ion conductive elastomer (ICE) with MXene artificial synapse. It successfully simulates the sensory behaviors of biological ANS and generates plastic neuroimpulse in response to real stimuli, allowing for the transformation from short-term memory to long-term memory.
Article
Chemistry, Analytical
Rong Zhang, Tiantian Hao, Shihui Hu, Kaiyang Wang, Shuhui Ren, Ziwei Tian, Yunfang Jia
Summary: In this work, a machine-learning-algorithm-based data analyzing method is developed for flexible electrolyte-gated graphene field effect transistors (Eg-GFETs) to address the bias-voltage-induced uncertainties. Ca2+ detection is used as a proof-of-concept. Eight regression models are trained with different machine learning algorithms, and the optimized model is obtained. The proposed method accurately determines Ca2+ concentration in a calibration-free way and simplifies the traditional calibration step in using Eg-GFET sensors.
Review
Chemistry, Multidisciplinary
Qianlong Zhao, Zhongjian Xie, Ya-Pei Peng, Kaiyang Wang, Huide Wang, Xiangnan Li, Hongwei Wang, Jingsheng Chen, Han Zhang, Xiaobing Yan
MATERIALS HORIZONS
(2020)