Structure of Tau filaments in Prion protein amyloidoses

Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation

(2021) Carolina Alquezar et al.   Frontiers in Neurology

Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607

(2021) Yang Shi et al.   ACTA NEUROPATHOLOGICA

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

(2020) Tamta Arakhamia et al.   CELL

Novel tau filament fold in corticobasal degeneration

(2020) Wenjuan Zhang et al.   NATURE

High resolution single particle Cryo-EM refinement using JSPR

(2020) Chen Sun et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease

(2020) Hendrik Wesseling et al.   CELL

Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules

(2019) Benjamin Falcon et al.   NATURE

Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer’s disease and PART

(2018) Sarah K. Kaufman et al.   ACTA NEUROPATHOLOGICA

Structures of filaments from Pick’s disease reveal a novel tau protein fold

(2018) Benjamin Falcon et al.   NATURE

Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold

(2018) Benjamin Falcon et al.   ACTA NEUROPATHOLOGICA

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET

(2018) Shannon L. Risacher et al.   Acta Neuropathologica Communications

Helical reconstruction in RELION

(2017) Shaoda He et al.   JOURNAL OF STRUCTURAL BIOLOGY

Variable tau accumulation in murine models with abnormal prion protein deposits

(2017) Pedro Piccardo et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

iPS Cell Cultures from a Gerstmann-Sträussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology

(2017) Andreu Matamoros-Angles et al.   MOLECULAR NEUROBIOLOGY

Cryo-EM structures of tau filaments from Alzheimer’s disease

(2017) Anthony W. P. Fitzpatrick et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy

(2016) Jamie C. Fong et al.   JOURNAL OF ALZHEIMERS DISEASE

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Phosphorylated human tau associates with mouse prion protein amyloid in scrapie-infected mice but does not increase progression of clinical disease

(2016) Brent Race et al.   Prion

Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8

(2016) Thomas J. Malia et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta

(2016) Ray Yu-Ruei Wang et al.   eLife

Whole-Exome Sequencing in Familial Parkinson Disease

(2016) Janice L. Farlow et al.   JAMA Neurology

Complete De Novo Assembly of Monoclonal Antibody Sequences

(2016) Ngoc Hieu Tran et al.   Scientific Reports

PART is part of Alzheimer disease

(2015) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Invited review: Frontotemporal dementia caused bymicrotubule-associated protein taugene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

(2015) Bernardino Ghetti et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Structural Impact of Tau Phosphorylation at Threonine 231

(2015) Martin Schwalbe et al.   STRUCTURE

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

ProteomeXchange provides globally coordinated proteomics data submission and dissemination

(2014) Juan A Vizcaíno et al.   NATURE BIOTECHNOLOGY

Proteopathic tau seeding predicts tauopathy in vivo

(2014) B. B. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer’s disease brain

(2013) Ayaho Dan et al.   Acta Neuropathologica Communications

The spectrum of disease in chronic traumatic encephalopathy

(2012) Ann C. McKee et al.   BRAIN

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Familial prion disease with alzheimer disease-like tau pathology and clinical phenotype

(2011) Suman Jayadev et al.   ANNALS OF NEUROLOGY

A Bayesian View on Cryo-EM Structure Determination

(2011) Sjors H.W. Scheres   JOURNAL OF MOLECULAR BIOLOGY

Phosphorylation of Tau at Thr212, Thr231, and Ser262Combined Causes Neurodegeneration

(2010) Alejandra D. Alonso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY