Clustering of Death Receptor for Apoptosis Using Nanoscale Patterns of Peptides

Proximity-induced caspase-9 activation on a DNA origami-based synthetic apoptosome

(2020) Bas J. H. M. Rosier et al.   Nature Catalysis

Design, optimization and analysis of large DNA and RNA nanostructures through interactive visualization, editing and molecular simulation

(2020) Erik Poppleton et al.   NUCLEIC ACIDS RESEARCH

Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers

(2020) Toon Verheyen et al.   NUCLEIC ACIDS RESEARCH

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

(2020) Rémi Veneziano et al.   Nature Nanotechnology

Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies

(2019) Alan Shaw et al.   Nature Nanotechnology

Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling

(2019) Liqiang Pan et al.   CELL

TRAIL-inspired multivalent dextran conjugates efficiently induce apoptosis upon DR5 receptor clustering

(2019) Hendrik Schneider et al.   CHEMBIOCHEM

DNA Nanotechnology-Enabled Drug Delivery Systems

(2018) Qinqin Hu et al.   CHEMICAL REVIEWS

Structural principles of tumor necrosis factor superfamily signaling

(2018) Éva S. Vanamee et al.   Science Signaling

Quantifying absolute addressability in DNA origami with molecular resolution

(2018) Maximilian T. Strauss et al.   Nature Communications

Structural principles of tumor necrosis factor superfamily signaling

(2018) Éva S. Vanamee et al.   Science Signaling

Effects of Design Choices on the Stiffness of Wireframe DNA Origami Structures

(2018) Erik Benson et al.   ACS Nano

TRAIL-death receptor endocytosis and apoptosis are selectively regulated by dynamin-1 activation

(2017) Carlos R. Reis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Synthesis of Triangulated DNA Origami Trusses

(2016) Michael Matthies et al.   NANO LETTERS

Quantitative super-resolution imaging with qPAINT

(2016) Ralf Jungmann et al.   NATURE METHODS

Designer nanoscale DNA assemblies programmed from the top down

(2016) R. Veneziano et al.   SCIENCE

DNA rendering of polyhedral meshes at the nanoscale

(2015) Erik Benson et al.   NATURE

Designing DNA nanodevices for compatibility with the immune system of higher organisms

(2015) Sunaina Surana et al.   Nature Nanotechnology

Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene

(2014) Tianyue Jiang et al.   ADVANCED MATERIALS

Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity

(2014) Jonathan D. Graves et al.   CANCER CELL

Spatial control of membrane receptor function using ligand nanocalipers

(2014) Alan Shaw et al.   NATURE METHODS

Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT

(2014) Ralf Jungmann et al.   NATURE METHODS

Polyhedra Self-Assembled from DNA Tripods and Characterized with 3D DNA-PAINT

(2014) R. Iinuma et al.   SCIENCE

Multivalent Scaffold Proteins as Superagonists of TRAIL Receptor 2-Induced Apoptosis

(2013) J. S. Swers et al.   MOLECULAR CANCER THERAPEUTICS

APG350 Induces Superior Clustering of TRAIL Receptors and Shows Therapeutic Antitumor Efficacy Independent of Cross-Linking via Fc  Receptors

(2013) C. Gieffers et al.   MOLECULAR CANCER THERAPEUTICS

Coarse-graining DNA for simulations of DNA nanotechnology

(2013) Jonathan P. K. Doye et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Multimerization of an Apoptogenic TRAIL-Mimicking Peptide by Using Adamantane-Based Dendrons

(2012) Giuseppe Lamanna et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Death Receptor 5 Networks That Are Highly Organized

(2012) Christopher C. Valley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics

(2012) L Y Dimberg et al.   ONCOGENE

Rapid Folding of DNA into Nanoscale Shapes at Constant Temperature

(2012) J.-P. J. Sobczak et al.   SCIENCE

Tug-of-War in Motor Protein Ensembles Revealed with a Programmable DNA Origami Scaffold

(2012) N. D. Derr et al.   SCIENCE

A primer to scaffolded DNA origami

(2011) Carlos Ernesto Castro et al.   NATURE METHODS

DNA Origami with Complex Curvatures in Three-Dimensional Space

(2011) D. Han et al.   SCIENCE

Multivalent DR5 Peptides Activate the TRAIL Death Pathway and Exert Tumoricidal Activity

(2010) V. Pavet et al.   CANCER RESEARCH

Single-molecule chemical reactions on DNA origami

(2010) Niels V. Voigt et al.   Nature Nanotechnology

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-1 and receptor-2 agonists for cancer therapy

(2009) Norma Lynn Fox et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Nanoscale Arrangement of Apoptotic Ligands Reveals a Demand for a Minimal Lateral Distance for Efficient Death Receptor Activation

(2009) Julia Ranzinger et al.   NANO LETTERS

Self-assembly of DNA into nanoscale three-dimensional shapes

(2009) Shawn M. Douglas et al.   NATURE

TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype

(2008) Monzur Rahman et al.   BREAST CANCER RESEARCH AND TREATMENT