Pharmacological and Therapeutic Approaches in the Treatment of Epilepsy

Epigenetic Therapeutic Intervention for a Rare Epilepsy Disorder

(2020) Silvienne C. Sint Jago et al.   Epilepsy Currents

Epigenome-wide association study of seizures in childhood and adolescence

(2020) Doretta Caramaschi et al.   Clinical Epigenetics

Current status of drug targets and emerging therapeutic strategies in the management of Alzheimer's disease

(2020) Shampa Ghosh et al.   Current Neuropharmacology

Epigenetic Neuropharmacology: Drugs Affecting the Epigenome in the Brain

(2020) Miklos Toth   Annual Review of Pharmacology and Toxicology

Cognition and memory impairment attenuation via reduction of oxidative stress in acute and chronic mice model of epilepsy using antiepileptogenic Nux vomica

(2020) Priya Mishra et al.   JOURNAL OF ETHNOPHARMACOLOGY

Efficacy of Cicuta virosa medicinal preparations against pentylenetetrazole-induced seizures

(2020) Priya Mishra et al.   EPILEPSY & BEHAVIOR

Behavioral interventions in epilepsy

(2019) Sheryl R. Haut et al.   CURRENT OPINION IN NEUROLOGY

AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

(2019) Vincenzo Salpietro et al.   Nature Communications

Advances in the Potential Biomarkers of Epilepsy

(2019) Dominik Kobylarek et al.   Frontiers in Neurology

Immediate and deferred epigenomic signatures of in vivo neuronal activation in mouse hippocampus

(2019) Jordi Fernandez-Albert et al.   NATURE NEUROSCIENCE

Epigenetics and epilepsy prevention: The therapeutic potential of adenosine and metabolic therapies

(2019) Detlev Boison et al.   NEUROPHARMACOLOGY

DNA methyltransferase isoforms expression in the temporal lobe of epilepsy patients with a history of febrile seizures

(2019) Laurence de Nijs et al.   Clinical Epigenetics

CHD2 epilepsy: epigenetics and the quest for precision medicine

(2019) Joseph D Symonds   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Ketogenic Diet: A New Light Shining on Old but Gold Biochemistry

(2019) Raffaella Longo et al.   Nutrients

Circulating microRNAs as potential biomarkers for genetic generalized epilepsies: a three microRNA panel

(2019) R. Martins‐Ferreira et al.   EUROPEAN JOURNAL OF NEUROLOGY

Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy

(2018) Daniel T. Pederick et al.   NEURON

Double-edged GABAergic synaptic transmission in seizures: The importance of chloride plasticity

(2018) Ying Wang et al.   BRAIN RESEARCH

Effect of Ketogenic Diet on Motor Functions and Daily Living Activities of Children With Multidrug-Resistant Epilepsy: A Prospective Study

(2018) Duygu Çubukçu et al.   JOURNAL OF CHILD NEUROLOGY

Increased stress and altered expression of histone modifying enzymes in brain are associated with aberrant behaviour in vitamin B12 deficient female mice

(2018) Shampa Ghosh et al.   NUTRITIONAL NEUROSCIENCE

Managing epilepsy-associated depression: Serotonin enhancers or serotonin producers?

(2017) Tanveer Singh et al.   EPILEPSY & BEHAVIOR

Epigenetic interventions for epileptogenesis: A new frontier for curing epilepsy

(2017) Iyan Younus et al.   PHARMACOLOGY & THERAPEUTICS

Epilepsy-associated genes

(2017) Jie Wang et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

The effects of herbal medicine on epilepsy

(2017) Wei Liu et al.   Oncotarget

Epigenomic maintenance through dietary intervention can facilitate DNA repair process to slow down the progress of premature aging

(2016) Shampa Ghosh et al.   IUBMB LIFE

The Biochemistry and Epigenetics of Epilepsy: Focus on Adenosine and Glycine

(2016) Detlev Boison   Frontiers in Molecular Neuroscience

Vitamin D3 for the Treatment of Epilepsy: Basic Mechanisms, Animal Models, and Clinical Trials

(2016) Kevin Pendo et al.   Frontiers in Neurology

A pharmacological basis of herbal medicines for epilepsy

(2015) Nikolaus J. Sucher et al.   EPILEPSY & BEHAVIOR

Animal models in epilepsy research: legacies and new directions

(2015) Brian P Grone et al.   NATURE NEUROSCIENCE

Pathologic role of neuronal nicotinic acetylcholine receptors in epileptic disorders: implication for pharmacological interventions

(2015) Mehdi Ghasemi et al.   REVIEWS IN THE NEUROSCIENCES

Epigenetics and Epilepsy

(2015) David C. Henshall et al.   Cold Spring Harbor Perspectives in Medicine

ILAE Official Report: A practical clinical definition of epilepsy

(2014) Robert S. Fisher et al.   EPILEPSIA

Drug treatment of epilepsy in adults

(2014) D. Schmidt et al.   BMJ-British Medical Journal

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

Mammalian Target of Rapamycin (mTOR) Inhibition: Potential for Antiseizure, Antiepileptogenic, and Epileptostatic Therapy

(2012) Robin C. C. Ryther et al.   Current Neurology and Neuroscience Reports

Evidence-based review on the natural history of the epilepsies

(2012) Dieter Schmidt et al.   CURRENT OPINION IN NEUROLOGY

Long-lasting pro-ictogenic effects induced in vivo by rat brain exposure to serum albumin in the absence of concomitant pathology

(2012) Federica Frigerio et al.   EPILEPSIA

The emerging role of DNA methylation in epileptogenesis

(2012) Katja Kobow et al.   EPILEPSIA

Correction of vitamin D deficiency improves seizure control in epilepsy: A pilot study

(2012) András Holló et al.   EPILEPSY & BEHAVIOR

Protocadherins mediate dendritic self-avoidance in the mammalian nervous system

(2012) Julie L. Lefebvre et al.   NATURE

Before Epilepsy Unfolds: Finding the epileptogenesis switch

(2012) Annamaria Vezzani   NATURE MEDICINE

Patterns of treatment response in newly diagnosed epilepsy

(2012) M. J. Brodie et al.   NEUROLOGY

The role of inflammation in epileptogenesis

(2012) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

A nonsense mutation in FMR1 causing fragile X syndrome

(2011) Karen Grønskov et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Drug-Resistant Epilepsy

(2011) Patrick Kwan et al.   NEW ENGLAND JOURNAL OF MEDICINE

The growing recognition of immunotherapy-responsive seizure disorders with autoantibodies to specific neuronal proteins

(2010) Angela Vincent et al.   CURRENT OPINION IN NEUROLOGY

Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009

(2010) Anne T. Berg et al.   EPILEPSIA

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

Selective changes in GABAA receptor subtypes in white matter neurons of patients with focal epilepsy

(2009) F. Loup et al.   BRAIN

Epilepsy, psychosocial and cognitive functioning

(2009) Jane McCagh et al.   EPILEPSY RESEARCH

Transcriptome Profiling Reveals TGF-  Signaling Involvement in Epileptogenesis

(2009) L. P. Cacheaux et al.   JOURNAL OF NEUROSCIENCE

Down-regulation of cerebellar 5-HT2C receptors in pilocarpine-induced epilepsy in rats: Therapeutic role of Bacopa monnieri extract

(2009) Amee Krishnakumar et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Vagus nerve stimulation in the treatment of refractory epilepsy

(2009) Andrew H. Milby et al.   Neurotherapeutics

Modern management of epilepsy: A practical approach

(2008) Christian E. Elger et al.   EPILEPSY & BEHAVIOR

The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial

(2008) Elizabeth G Neal et al.   LANCET NEUROLOGY

Outcomes of epilepsy surgery in adults and children

(2008) Susan Spencer et al.   LANCET NEUROLOGY

Nonadherence to antiepileptic drugs and increased mortality: Findings from the RANSOM Study

(2008) E. Faught et al.   NEUROLOGY