An engineered probiotic secreting Sj16 ameliorates colitis via Ruminococcaceae/butyrate/retinoic acid axis

A Novel Strategy for Treating Inflammatory Bowel Disease by Targeting Delivery of Methotrexate through Glucan Particles

(2020) Ying Sun et al.   Advanced Healthcare Materials

Heparin‐Coated Albumin Nanoparticles for Drug Combination in Targeting Inflamed Intestine

(2020) Sufeng Zhang et al.   Advanced Healthcare Materials

Risk variants disrupting enhancers of TH1 and TREG cells in type 1 diabetes

(2019) Peng Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation

(2019) Yanan S Zhang et al.   EMBO JOURNAL

Schistosoma mansoni worm infection regulates the intestinal microbiota and susceptibility to colitis.

(2019) Achilleas Floudas et al.   INFECTION AND IMMUNITY

Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases

(2019) Konrad Aden et al.   GASTROENTEROLOGY

Flagellin hypervariable region determines symbiotic properties of commensal Escherichia coli strains

(2019) Alex Steimle et al.   PLOS BIOLOGY

Innate lymphoid cells link gut microbes with mucosal T cell immunity

(2019) Jim G. Castellanos et al.   Gut Microbes

Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis

(2018) Marion Darnaud et al.   GASTROENTEROLOGY

Faecalibacterium prausnitzii Produces Butyrate to Maintain Th17/Treg Balance and to Ameliorate Colorectal Colitis by Inhibiting Histone Deacetylase 1

(2018) Lixing Zhou et al.   INFLAMMATORY BOWEL DISEASES

The association of diet, gut microbiota and colorectal cancer: what we eat may imply what we get

(2018) Jia Yang et al.   Protein & Cell

The Administration of Escherichia coli Nissle 1917 Ameliorates Development of DSS-Induced Colitis in Mice

(2018) Alba Rodríguez-Nogales et al.   Frontiers in Pharmacology

Hookworm Secreted Extracellular Vesicles Interact With Host Cells and Prevent Inducible Colitis in Mice

(2018) Ramon M. Eichenberger et al.   Frontiers in Immunology

Inflammatory bowel disease: DCs sense LTB4 to drive TH1 and TH17 differentiation

(2018) Bhagawat C. Subramanian   Cellular & Molecular Immunology

Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis

(2018) Nicholas A. Scott et al.   Science Translational Medicine

Gut microbiome structure and metabolic activity in inflammatory bowel disease

(2018) Eric A. Franzosa et al.   Nature Microbiology

Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

(2017) Siew C Ng et al.   LANCET

Retinoic Acid and Immune Homeostasis: A Balancing Act

(2017) Martje N. Erkelens et al.   TRENDS IN IMMUNOLOGY

Schistosoma japonicum attenuates dextran sodium sulfate-induced colitis in mice via reduction of endoplasmic reticulum stress

(2017) Ya Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

rSj16 Protects against DSS-Induced Colitis by Inhibiting the PPAR-α Signaling Pathway

(2017) Lifu Wang et al.   Theranostics

Alpha-Tocopheryl Succinate-Conjugated G5 PAMAM Dendrimer Enables Effective Inhibition of Ulcerative Colitis

(2017) Yunan Wang et al.   Advanced Healthcare Materials

Exosomes Derived from Dendritic Cells Treated with Schistosoma japonicum Soluble Egg Antigen Attenuate DSS-Induced Colitis

(2017) Lifu Wang et al.   Frontiers in Pharmacology

SIGNing a symbiotic treaty with gut microbiota

(2015) G. Lugo-Villarino et al.   EMBO JOURNAL

Retinoic Acid Is Essential for Th1 Cell Lineage Stability and Prevents Transition to a Th17 Cell Program

(2015) Chrysothemis C. Brown et al.   IMMUNITY

Mucosal Barrier Depletion and Loss of Bacterial Diversity are Primary Abnormalities in Paediatric Ulcerative Colitis

(2015) Misagh Alipour et al.   Journal of Crohns & Colitis

Berberine ameliorates TNBS induced colitis by inhibiting inflammatory responses and Th1/Th17 differentiation

(2015) Chengzhen Li et al.   MOLECULAR IMMUNOLOGY

All-trans retinoic acid attenuates experimental colitis through inhibition of NF-κB signaling

(2014) Kai Hong et al.   IMMUNOLOGY LETTERS

Secretory products of helminth parasites as immunomodulators

(2014) William Harnett   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A Transgenic Probiotic Secreting a Parasite Immunomodulator for Site-Directed Treatment of Gut Inflammation

(2014) Rose A Whelan et al.   MOLECULAR THERAPY

Lung-resident tissue macrophages generate Foxp3+regulatory T cells and promote airway tolerance

(2013) Pejman Soroosh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Unique roles of Schistosoma japonicum protein Sj16 to induce IFN-γ and IL-10 producing CD4+CD25+ regulatory T cells in vitro and in vivo

(2012) X. J. SUN et al.   PARASITE IMMUNOLOGY

Effects of a recombinant schistosomal-derived anti-inflammatory molecular (rSj16) on the lipopolysaccharide (LPS)-induced activated RAW264.7

(2012) Xi Sun et al.   PARASITOLOGY RESEARCH

Fighting malaria with engineered symbiotic bacteria from vector mosquitoes

(2012) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

E. coli Nissle 1917 Affects Salmonella Adhesion to Porcine Intestinal Epithelial Cells

(2011) Peter Schierack et al.   PLoS One

rSj16, a recombinant protein of Schistosoma japonicum-derived molecule, reduces severity of the complete Freund’s adjuvant-induced adjuvant arthritis in rats’ model

(2010) X. SUN et al.   PARASITE IMMUNOLOGY

IL-22+ CD4+ T Cells Are Associated with Therapeutic Trichuris trichiura Infection in an Ulcerative Colitis Patient

(2010) M. J. Broadhurst et al.   Science Translational Medicine

All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis

(2009) Aiping Bai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helminth antigen-based strategy to ameliorate inflammation in an experimental model of colitis

(2008) Y. Motomura et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY