VEGF‐C/VEGFR‐3 axis protects against pressure‐overload induced cardiac dysfunction through regulation of lymphangiogenesis

Lymphatic and Immune Cell Cross-Talk Regulates Cardiac Recovery After Experimental Myocardial Infarction

(2020) Mahmoud Houssari et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A dual role for Tbx1 in cardiac lymphangiogenesis through genetic interaction with Vegfr3

(2020) Stefania Martucciello et al.   FASEB JOURNAL

Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension

(2020) LouJin Song et al.   eLife

Adrenomedullin Induces Cardiac Lymphangiogenesis After Myocardial Infarction and Regulates Cardiac Edema Via Connexin 43

(2019) Claire E. Trincot et al.   CIRCULATION RESEARCH

Lymphatic system identification, pathophysiology and therapy in the cardiovascular diseases

(2019) Dan Hu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

CD1d-dependent natural killer T cells attenuate angiotensin II-induced cardiac remodelling via IL-10 signalling in mice

(2018) Hong-Xia Wang et al.   CARDIOVASCULAR RESEARCH

CXCL1–CXCR2 axis mediates angiotensin II-induced cardiac hypertrophy and remodelling through regulation of monocyte infiltration

(2018) Lei Wang et al.   EUROPEAN HEART JOURNAL

The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction

(2018) Joaquim Miguel Vieira et al.   JOURNAL OF CLINICAL INVESTIGATION

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

(2018) Hwee Ying Lim et al.   IMMUNITY

Impact of Lymphangiogenesis on Cardiac Remodeling After Ischemia and Reperfusion Injury

(2018) Yuuki Shimizu et al.   Journal of the American Heart Association

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction

(2018) Taina Vuorio et al.   Scientific Reports

Resveratrol as a new inhibitor of immunoproteasome prevents PTEN degradation and attenuates cardiac hypertrophy after pressure overload

(2018) Chen Chen et al.   Redox Biology

Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial InfarctionCLINICAL PERSPECTIVE

(2016) Orianne Henri et al.   CIRCULATION

Lymphatic System in Cardiovascular Medicine

(2016) Aleksanteri Aspelund et al.   CIRCULATION RESEARCH

VEGF-C and VEGF-C156S in the pro-lymphangiogenic growth factor therapy of lymphedema: a large animal study

(2015) Mikko T. Visuri et al.   ANGIOGENESIS

Therapeutic lymphangiogenesis ameliorates established acute lung allograft rejection

(2015) Ye Cui et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac lymphatics are heterogeneous in origin and respond to injury

(2015) Linda Klotz et al.   NATURE

Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet

(2015) Sinem Karaman et al.   Molecular Metabolism

VEGF-C–dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease

(2014) Silvia D’Alessio et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of Toll-like receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation

(2013) Lei Wang et al.   CARDIOVASCULAR RESEARCH

Mutation in Vascular Endothelial Growth Factor-C, a Ligand for Vascular Endothelial Growth Factor Receptor-3, Is Associated With Autosomal Dominant Milroy-Like Primary Lymphedema

(2013) Kristiana Gordon et al.   CIRCULATION RESEARCH

Differential expression of vascular endothelial growth factor isoforms and receptor subtypes in the infarcted heart

(2012) Tieqiang Zhao et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Biological Basis of Therapeutic Lymphangiogenesis

(2011) Camilla Norrmén et al.   CIRCULATION

VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis

(2010) Luqing Zhang et al.   CELL RESEARCH

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

(2009) Trung H.M. Pham et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NFATc1 regulates lymphatic endothelial development

(2009) Rishikesh M. Kulkarni et al.   MECHANISMS OF DEVELOPMENT

Molecular Biology and Pathology of Lymphangiogenesis

(2008) Terhi Karpanen et al.   Annual Review of Pathology-Mechanisms of Disease

Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D Is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos

(2008) P. Haiko et al.   MOLECULAR AND CELLULAR BIOLOGY